Search Results - "Filho, Evaldo"
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1
Unraveling the Metabolomic Profile and Bioactivities of the Paratoid Gland Secretion from Rhinella granulosa
Published in Journal of the Brazilian Chemical Society (01-10-2023)“…Toads of the Rhinella genus have a pair of paratoid glands that store biological secretions of high toxicity and varied chemical composition, rich in…”
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2
Chemical Constituents and Cytotoxic Activity of Rhinella jimi (Anura: Bufonidae)
Published in Journal of the Brazilian Chemical Society (01-05-2021)“…Rhinella jimi toads (Stevaux, 2002) belong to the Bufonidae family, are endemic in the Brazilian Northeast and are commonly found during rainy periods. In…”
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3
Bufadienolides from amphibians: A promising source of anticancer prototypes for radical innovation, apoptosis triggering and Na+/K+-ATPase inhibition
Published in Toxicon (Oxford) (01-03-2017)“…Amphibians present pharmacologically active aliphatic, aromatic and heterocyclic molecules in their skin as defense against microorganisms, predators and…”
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4
Prenatal diagnosis of fetal left ventricular diverticulum: 3D virtual and physical reconstruction models
Published in Journal of clinical ultrasound (01-05-2024)“…Congenital diverticulum is a very rare congenital heart disease. 3D virtual and physical models from ultrasound scan data provide a spatial visualization and…”
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5
Calcium overload-induced arrhythmia is suppressed by farnesol in rat heart
Published in European journal of pharmacology (15-09-2019)“…Cardiac arrhythmias are among the most important pathologies that lead to sudden death. The discovery of new therapeutic options against arrhythmias with low…”
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6
Tumor risk markers in recurrent respiratory papillomatosis
Published in Brazilian journal of otorhinolaryngology (01-03-2023)“…This study aims to investigate the pattern of immunoexpression of proteins p16, p53 and Ki-67 in RRP, as well as to evaluate its influence on the number of…”
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7
Chemical Profile, Antioxidant and Antimicrobial Activities of Combretum lanceolatum Pohl ex Eichler. (Combretaceae)
Published in Journal of the Brazilian Chemical Society (2025)“…Compared to other species, components of Combretum lanceolatum are still with few data reported in the literature. This work describes the compounds…”
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8
Toxic profile of marinobufagin from poisonous Amazon toads and antitumoral effects on human colorectal carcinomas
Published in Journal of ethnopharmacology (28-06-2023)“…South Americans natives have extensively used the toad “kururu” to reduce/treat skin infections, cutaneous lesions and sores. They release secretions rich in…”
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9
Cytotoxicity potential of chemical constituents isolated and derivatised from Rhinella marina venom
Published in Toxicon (Oxford) (30-04-2021)“…Chemical compounds from skin secretions from toads of Bufonidae family have been long-studied. In the search for new molecules with pharmacological action, the…”
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10
Comparative study of composition of methanolic extracts of the paratoid gland secretions (PGS) of Rhinella jimi (cururu toad) from northeastern Brazil: Gender, seasonality and geographic occurrence
Published in Toxicon (Oxford) (30-07-2022)“…Toads belonging to the Bufonidae family have a pair of paratoid glands that store highly toxic a biological secretion with varied chemical composition, that…”
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11
New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells
Published in Steroids (01-12-2019)“…•A bufadienolide extracted from cane toad (compound 1) inhibits Na,K-ATPase.•Compound 1 decreases Na,K-ATPase expression.•Compound 1 activates caspase 3 and 9…”
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12
Effect of Pulsed Therapeutic Ultrasound and Diosmin on Skeletal Muscle Oxidative Parameters
Published in Ultrasound in medicine & biology (01-02-2018)“…Cyclodextrins (CDs) have been widely used as a promising alternative in the formation of inclusion complexes with poorly soluble molecules. From this…”
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13
Nerol Attenuates Ouabain-Induced Arrhythmias
Published in Evidence-based complementary and alternative medicine (01-01-2019)“…Nerol (C10H18O) is a monoterpene found in many essential oils, such as lemon balm and hop. In this study, we explored the contractile and electrophysiological…”
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14
Geraniol Blocks Calcium and Potassium Channels in the Mammalian Myocardium: Useful Effects to Treat Arrhythmias
Published in Basic & clinical pharmacology & toxicology (01-12-2014)“…Geraniol is a monoterpene present in several essential oils, and it is known to have a plethora of pharmacological activities. In this study, we explored the…”
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15
Topical application of (S)-(–)-limonene is as effective as phonophoresis for improving oxidative parameters of injured skeletal muscle in rats
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-12-2020)“…The aim of this study is to investigate the effects of limonene, alone or associated with therapeutic ultrasound, on oxidative stress following skeletal muscle…”
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16
Nanoencapsulated α-terpineol attenuates neuropathic pain induced by chemotherapy through calcium channel modulation
Published in Polymer bulletin (Berlin, Germany) (01-03-2023)“…Although chemotherapy-induced peripheral neuropathy is one of the main medical complaints of cancer patients, there are currently no specific drugs for the…”
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17
Evaluation of antimutagenic and cytotoxic activity of skin secretion extract of Rhinella marina and Rhaebo guttatus (Anura, Bufonidae)
Published in Acta amazonica (01-04-2019)“…ABSTRACT The skin secretion from toads of the Bufonidae family has great potential in the search for new active compounds to be used as drug candidates in…”
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18
Multi-response Optimization of a Solvent System for the Extraction of Antioxidants Polyphenols from Jambolan Fruit (Syzygium cumini (L.) Skeels)
Published in Food analytical methods (2022)“…The identification of bio-polyphenols from jambolan fruit is of great interest and requires extraction conditions that preserve their bioactivities. This study…”
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19
Analysis of Surgical Recurrence after Larynx Microsurgery for Benign Lesions
Published in International Archives of Otorhinolaryngology (01-10-2021)“…Abstract Introduction The study of larynx lesions is of great importance. More than 50% of people with vocal complaints have benign vocal fold alterations and…”
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20
Dissection of the Effects of Quercetin on Mouse Myocardium
Published in Basic & clinical pharmacology & toxicology (01-06-2017)“…Quercetin is a plant flavonoid with several biological activities. This study aimed to describe quercetin effects on contractile and electrophysiological…”
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