Search Results - "Filer, Crist N."

Luminescence enhancement by deuterium by Filer, Crist N.

“…Created literally at the dawn of time, deuterium has been extremely valuable in so many chemistry roles. The subject of this review focuses on one deuterium…”
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On the Uncatalyzed Thermal Conversion of Cannabidiol to Delta-9-Tetrahydrocannabinol by Filer, Crist N

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Cannabinoid Photochemistry: An Underexplored Opportunity by Filer, Crist N

“…Photochemistry is a powerful synthetic tool resulting in the construction of unique substances. Remarkably, photochemistry has been relatively underexplored in…”
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Cannabinoid crystal polymorphism by Filer, Crist N

“…Because cannabinoids are usually amorphous solids, the thought that some of them may also exist in distinctly different crystal polymorphic forms might at…”
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Cannabinoids as Cocrystals by Filer, Crist N.

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MicroED and cannabinoid research by Filer, Crist N

“…MicroED has recently emerged as a convenient and powerful tool for the unequivocal structure determination of small molecules and it could likely be used in…”
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Minnesota wild hemp: a crucial botanical source in early cannabinoid discovery by Filer, Crist N

“…Renewed and sustained Cannabis chemistry exploration was initiated by Roger Adams at the University of Illinois Chemistry Department with cooperation from the…”
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Tritium decay catastrophe by Filer, Crist N.

“…The phenomenon of tritium decay catastrophe is introduced. A technical example is provided regarding the radioligand [methoxy-3H] levosulpiride whose long-term…”
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A synthesis of [3H] cocaine at high specific activity by Filer, Crist N.

“…An efficient procedure is described to tritiate cocaine at high specific activity. Several tritium labelling methods were considered and evaluated against the…”
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Anti-COVID-19 natural product 5-aminolevulinic acid: its tritium labelling by Filer, Crist N.

“…This paper discloses a convenient and effective tritiation of 5-aminolevulinic acid (5-ALA). The synthetic method involves a direct tritium labelling of 5-ALA…”
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Artificial intelligence and natural product research by Filer, Crist N

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Creation of a nitrosamine library labelled with 14C or tritium by Filer, Crist N.

“…Cancer continues to be a leading cause of global death despite decades of research on its prevention and cure. In the mid-twentieth century, anecdotal evidence…”
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The remarkable reimagining of psilocybin by Filer, Crist N.

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Acidic Cannabinoid Decarboxylation by Filer, Crist N

“…is a valuable plant, cultivated by humans for millennia. However, it has only been in the past several decades that biologists have begun to clarify the…”
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Radiolabelling of bisphenol A and several related analogues by Filer, Crist N., Pounds, Scot, Wright, Christopher

“…This paper describes the synthesis and characterization of bisphenol A and several closely associated derivatives with 14C and tritium. •This paper describes…”
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Terminal alkyne semi-tritiation with Lindlar catalyst and its mechanism implications by Filer, Crist N.

“…It has been nearly 70 years since the discovery of Lindlar catalyst and its valuable ability to semi-hydrogenate alkynes to cis olefins. The Lindlar catalyst…”
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Ibotenic acid: on the mechanism of its conversion to [3H] muscimol by Filer, Crist N.

“…Muscimol is a small but structurally unique isoxazole alkaloid isolated from the mushroom Amanita muscaria . Because of its potent gamma aminobutyric acid…”
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Delta-9-Tetrahydrocannabinolic Acid B: A Mechanism for its Formation in Cannabis by Filer, Crist N

“…There appears to be consensus among biologists that delta-9-tetrahydrocannabinolic acid A (THCA-A) is the exclusive product of the enzyme THCA synthase. This…”
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Dofetilide: tritium labelling by several methods by Egan, Judith A., Filer, Crist N., Pounds, Scot

“…Despite decades of research, heart disease remains a burden on global health, especially in developed countries. Among problematic cardiovascular indications,…”
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An effective and scalable 14C radiolabelling of several biogenic indole derivatives at high specific activity by Filer, Crist N., Orphanos, Demetri

“…An efficient method is described to radiolabel several biogenic indole derivatives with carbon-14 at high specific activity. •This paper describes the…”
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