Search Results - "Filburn, C"

Bioavailability of a silybin-phosphatidylcholine complex in dogs by FILBURN, C.R, KETTENACKER, R, GRIFFIN, D.W

“…Liver dysfunction often is associated with an imbalance in the production and removal of free radicals derived from oxygen and nitrogen and has been managed…”
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Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes by Zorov, D B, Filburn, C R, Klotz, L O, Zweier, J L, Sollott, S J

“…We sought to understand the relationship between reactive oxygen species (ROS) and the mitochondrial permeability transition (MPT) in cardiac myocytes based on…”
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Mitochondrial biogenesis during cellular differentiation by Moyes, C D, Mathieu-Costello, O A, Tsuchiya, N, Filburn, C, Hansford, R G

“…Mitochondrial biogenesis was studied during differentiation of two immortalized cell lines (C2C12, 3T3) with enzyme measurements, Northern blots, and…”
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Affinity chromatography of protein kinase C-phorbol ester receptor on polyacrylamide-immobilized phosphatidylserine by Uchida, T, Filburn, C R

“…An affinity column, prepared by immobilizing phosphatidylserine and cholesterol in polyacrylamide, was utilized in the purification of protein kinase C…”
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Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA by Anson, R. Michael, Croteau, Deborah L., Stierum, Rob H., Filburn, Charles, Parsell, Robin, Bohr, Vilhelm A.

“…Photoactivated methylene blue was used to damage purified DNA and the mitochondrial DNA (mtDNA) of human fibroblasts in culture. The primary product of this…”
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Structure/function relationships in hexokinase. Site-directed mutational analyses and characterization of overexpressed fragments implicate different functions for the N- and C-terminal halves of the enzyme by Arora, K.K., Filburn, C.R., Pedersen, P.L.

“…Hexokinases are comprised of two highly homologous approximately 50-kDa halves and are product-inhibited by glucose-6-P. Four amino acid residues, Ser603,…”
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Alpha-adrenergic regulation of phosphoinositide metabolism and protein kinase C in isolated cardiac myocytes by Kaku, T, Lakatta, E, Filburn, C

“…alpha 1-Adrenergic regulation of phosphoinositide metabolism and protein kinase C translocation was studied in isolated rat cardiac myocytes. Exposure of…”
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Age-related defect in signal transduction during lectin activation of murine T lymphocytes by Proust, JJ, Filburn, CR, Harrison, SA, Buchholz, MA, Nordin, AA

“…Interleukin 2 (IL-2) production and recognition are clearly involved in the age-associated proliferative defect of mitogen-stimulated T lymphocytes. The…”
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Purinergic regulation of cytosolic calcium and phosphoinositide metabolism in rat osteoblast‐like osteosarcoma cells by Kumagai, Hiromichi, Sacktor, Bertram, Filburn, Charles R.

“…We have shown that ATP increases cytosolic Ca2+ in UMR‐106 cells through P2‐purinergic receptor stimulation (Calcif Tissue Int 45:251‐254). This response was…”
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Mitochondrial electron transport chain activities and DNA deletions in regions of the rat brain by Filburn, Charles R., Edris, Wade, Tamatani, Michio, Hogue, Barbara, Kudryashova, Irina, Hansford, Richard G.

“…Deletions in human mitochondrial DNA cause various mitochondrial myopathies and increase markedly with age in highly oxidative tissues, but exhibit a…”
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Glucose phosphorylation. Site-directed mutations which impair the catalytic function of hexokinase by Arora, K K, Filburn, C R, Pedersen, P L

“…Recent studies from this and other laboratories have resulted in the cloning and sequencing of hexokinases from a variety of tissues including yeast, human…”
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Detection and quantitation by competitive PCR of an age-associated increase in a 4.8-kb deletion in rat mitochondrial DNA by Edris, W, Burgett, B, Stine, O C, Filburn, C R

“…Recent studies on human tissues have shown that the quantity of partially deleted mitochondrial DNA (mtDNA) increases with age. In this study, mtDNAs from the…”
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Parathyroid hormone 1-34, but not 3-34 or 7-34, transiently translocates protein kinase C in cultured renal (OK) cells by Tamura, T, Sakamoto, H, Filburn, C R

“…While protein kinase C (PKC) appears to play a role in the action of PTH in renal cells, direct evidence of activation by PTH is lacking. Rat PTH (1-34) caused…”
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Effect of aging on striatal dopamine receptor subtypes in Wistar rats by Henry, J M, Filburn, C R, Joseph, J A, Roth, G S

“…Both D1 and D2 dopamine receptor subtypes are lost from striata as Wistar rats age. The magnitude of loss differs slightly for the two subtypes (approximately…”
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Contractile and biochemical correlates of beta-adrenergic stimulation of the aged heart by Guarnieri, T, Filburn, C R, Zitnik, G, Roth, G S, Lakatta, E G

“…The age dependence of contractile and associated biochemical parameters of basal- and catecholamine-stimulated myocardial contractile performance was…”
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Parathyroid hormone regulation of cytosolic Ca2+ in rat proximal tubules by Filburn, C R, Harrison, S

“…The effect of parathyroid hormone (PTH) on cytosolic Ca2+ was studied on suspensions of purified rat renal proximal tubules using the fluorescent indicator…”
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Impaired insulin secretion of aging: Role of renal failure and hyperparathyroidism by Massry, Shaul G., Fadda, George Z., Zhou, Xin-Jin, Chandrasoma, Parakrama, Cheng, Linda, Filburn, Charles R.

“…Impaired insulin secretion of aging: Role of renal failure and hyperparathyroidism. Available data indicate that insulin secretion is impaired with aging…”
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beta-Adrenergic regulation of protein phosphorylation and its relationship to exocrine secretion in dispersed rat parotid gland acinar cells by Baum, B J, Freiberg, J M, Ito, H, Roth, G S, Filburn, C R

“…The possible role of cyclic AMP-mediated phosphorylation events in the regulation of exocrine secretion after beta-adrenergic stimulation was examined in vitro…”
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Phorbol Ester and Dioctanoylglycerol Stimulate Membrane Association of Protein Kinase C and Have a Negative Inotropic Effect Mediated by Changes in Cytosolic Ca2+ in Adult Rat Cardiac Myocytes by Capogrossi, Maurizio C, Kaku, Takashi, Filburn, Charles R, Pelto, Don J, Hansford, Richard G, Spurgeon, Harold A, Lakatta, Edward G

“…We used left ventricular myocytes from adult rats to investigate the effect of 4β-phorbol 12-myristate 13-acetate (PMA) and of sn-1,2-dioctanoylglycerol…”
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Development of dopamine receptor denervation supersensitivity in the neostriatum of the senescent rat by Joseph, J A, Filburn, C R, Roth, G S

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