Search Results - "Filardy, Alessandra A."

All- Trans Retinoic Acid Promotes an M1- to M2-Phenotype Shift and Inhibits Macrophage-Mediated Immunity to Leishmania major by Vellozo, Natália S, Pereira-Marques, Sâmara T, Cabral-Piccin, Mariela P, Filardy, Alessandra A, Ribeiro-Gomes, Flávia L, Rigoni, Thaís S, DosReis, George A, Lopes, Marcela F

“…As key cells, able to host and kill parasites, inflammatory monocytes/macrophages are potential vaccine and therapeutic targets to improve immune responses in…”
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RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages by Rigoni, Thaís S, Vellozo, Natália S, Cabral-Piccin, Mariela, Fabiano-Coelho, Laryssa, Lopes, Ulisses G, Filardy, Alessandra A, DosReis, George A, Lopes, Marcela F

“…Macrophages host infection, which causes cutaneous Leishmaniasis in humans. In the murine model, resistance to infection depends on the host immunity mediated…”
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The PGE2/IL-10 Axis Determines Susceptibility of B-1 Cell-Derived Phagocytes (B-1CDP) to Leishmania major Infection by Arcanjo, Angélica F, LaRocque-de-Freitas, Isabel F, Rocha, Juliana Dutra B, Zamith, Daniel, Costa-da-Silva, Ana Caroline, Nunes, Marise Pinheiro, Mesquita-Santos, Fabio P, Morrot, Alexandre, Filardy, Alessandra A, Mariano, Mario, Bandeira-Melo, Christianne, DosReis, George A, Decote-Ricardo, Debora, Freire-de-Lima, Célio Geraldo

“…B-1 cells can be differentiated from B-2 cells because they are predominantly located in the peritoneal and pleural cavities and have distinct phenotypic…”
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Trypanosoma cruzi Infection Induces Cellular Stress Response and Senescence-Like Phenotype in Murine Fibroblasts by Guimarães-Pinto, Kamila, Nascimento, Danielle Oliveira, Corrêa-Ferreira, Antonia, Morrot, Alexandre, Freire-de-Lima, Celio G, Lopes, Marcela F, DosReis, George A, Filardy, Alessandra A

“…infects and replicates within a wide variety of immune and non-immune cells. Here, we investigated early cellular responses induced in NIH-3T3 fibroblasts upon…”
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Axl receptor induces efferocytosis, dampens M1 macrophage responses and promotes heart pathology in Trypanosoma cruzi infection by Rigoni, Thaís S., Vellozo, Natália S., Guimarães-Pinto, Kamila, Cabral-Piccin, Mariela, Fabiano-Coelho, Laryssa, Matos-Silva, Thayane C., Filardy, Alessandra A., Takiya, Christina M., Lopes, Marcela F.

“…Adaptive immunity controls Trypanosoma cruzi infection, but the protozoan parasite persists and causes Chagas disease. T cells undergo apoptosis, and the…”
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Infection with Leishmania major induces a cellular stress response in macrophages by Filardy, Alessandra A, Costa-da-Silva, Ana Caroline, Koeller, Carolina M, Guimarães-Pinto, Kamila, Ribeiro-Gomes, Flávia L, Lopes, Marcela F, Heise, Norton, Freire-de-Lima, Célio G, Nunes, Marise P, DosReis, George A

“…We investigated early cellular responses induced by infection with Leishmania major in macrophages from resistant C57/BL6 mice. Infection increased production…”
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Neutrophils increase or reduce parasite burden in Trypanosoma cruzi-infected macrophages, depending on host strain: role of neutrophil elastase by Luna-Gomes, Tatiana, Filardy, Alessandra A, Rocha, Juliana Dutra B, Decote-Ricardo, Debora, LaRocque-de-Freitas, Isabel Ferreira, Morrot, Alexandre, Bozza, Patrícia T, Castro-Faria-Neto, Hugo C, DosReis, George A, Nunes, Marise P, Freire-de-Lima, Célio G

“…Neutrophils are involved in the initial steps of most responses to pathogens and are essential components of the innate immune response. Due to the ability to…”
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Cellular Stress and Senescence Induction during Trypanosoma cruzi Infection by Guimarães-Pinto, Kamila, Ferreira, Jesuíno R. M., da Costa, André L. A., Morrot, Alexandre, Freire-de-Lima, Leonardo, Decote-Ricardo, Debora, Freire-de-Lima, Celio Geraldo, Filardy, Alessandra A.

“…Chagas disease (CD) is a neglected tropical disease caused by Trypanosoma cruzi infection that, despite being discovered over a century ago, remains a public…”
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The intestinal microenvironment shapes macrophage and dendritic cell identity and function by Filardy, Alessandra A., Ferreira, Jesuino R.M., Rezende, Rafael M., Kelsall, Brian L., Oliveira, Rafael P.

“…•Different intestinal niches harbor distinct macrophage and DC subpopulations.•Macrophages and DCs induce tolerance and immunity in the gut.•Local…”
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Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages by Filardy, Alessandra A, Pires, Dayana R, Nunes, Marise P, Takiya, Christina M, Freire-de-Lima, Celio G, Ribeiro-Gomes, Flavia L, DosReis, George A

“…Clearance of apoptotic exudate neutrophils (efferocytosis) induces either pro- or anti-inflammatory responses in mouse macrophages depending on host genetic…”
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Efferocytosis in lung mucosae: implications for health and disease by Guimarães-Pinto, Kamila, Maia, Ester P., Ferreira, Jesuino R.M., Filardy, Alessandra A.

“…•Efferocytosis receptors are key players to regulate and control lung homeostasis•Efferocytosis impairment boosts chronic lung inflammatory diseases…”
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Macrophages and neutrophils cooperate in immune responses to Leishmania infection by Filardy, Alessandra A, Pires, Dayana R, DosReis, George A

“…Neutrophils and macrophages are phagocytic cells that cooperate during inflammation and tissue repair. Neutrophils undergo apoptosis and are engulfed by…”
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Proinflammatory Clearance of Apoptotic Neutrophils Induces an IL-12lowIL-10high Regulatory Phenotype in Macrophages by Filardy, Alessandra A., Pires, Dayana R., Nunes, Marise P., Takiya, Christina M., Freire-de-Lima, Celio G., Ribeiro-Gomes, Flavia L., DosReis, George A.

“…Abstract Clearance of apoptotic exudate neutrophils (efferocytosis) induces either pro- or anti-inflammatory responses in mouse macrophages depending on host…”
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Post-transcriptional control of NLRP3 inflammasome activation in colonic macrophages by Filardy, Alessandra A., He, Jianping, Bennink, Jack, Yewdell, Jonathan, Kelsall, Brian L.

“…Colonic macrophages (cMPs) are important for intestinal homeostasis as they kill microbes yet produce regulatory cytokines. Activity of the NLRP3 inflammasome,…”
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The PGE.sub.2/IL-10 Axis Determines Susceptibility of B-1 Cell-Derived Phagocytes (B-1CDP) to Leishmania major Infection by Arcanjo, Angélica F, LaRocque-de-Freitas, Isabel F, Rocha, Juliana Dutra B, Zamith, Daniel, Costa-da-Silva, Ana Caroline, Nunes, Marise Pinheiro, Mesquita-Santos, Fabio P, Morrot, Alexandre, Filardy, Alessandra A, Mariano, Mario, Bandeira-Melo, Christianne, DosReis, George A, Decote-Ricardo, Debora, Freire-de-Lima, Célio Geraldo

“…B-1 cells can be differentiated from B-2 cells because they are predominantly located in the peritoneal and pleural cavities and have distinct phenotypic…”
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The PGE2/IL-10 Axis Determines Susceptibility of B-1 Cell-Derived Phagocytes (B-1CDP) to Leishmania major Infection: e0124888 by Arcanjo, Angelica F, LaRocque-de-Freitas, Isabel F, Rocha, Juliana DutraB, Zamith, Daniel, Costa-da-Silva, Ana Caroline, Nunes, Marise Pinheiro, Mesquita-Santos, Fabio P, Morrot, Alexandre, Filardy, Alessandra A, Mariano, Mario

“…B-1 cells can be differentiated from B-2 cells because they are predominantly located in the peritoneal and pleural cavities and have distinct phenotypic…”
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Neutrophils Increase or Reduce Parasite Burden in Trypanosoma cruzi-Infected Macrophages, Depending on Host Strain: Role of Neutrophil Elastase: e90582 by Luna-Gomes, Tatiana, Filardy, Alessandra A, Rocha, Juliana DutraB, Decote-Ricardo, Debora, LaRocque-de-Freitas, Isabel Ferreira, Morrot, Alexandre, Bozza, Patricia T, Castro-Faria-Neto, Hugo C, DosReis, George A, Nunes, Marise P

“…Neutrophils are involved in the initial steps of most responses to pathogens and are essential components of the innate immune response. Due to the ability to…”
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Infection with Leishmania major Induces a Cellular Stress Response in Macrophages: e85715 by Filardy, Alessandra A, Costa-da-Silva, Ana Caroline, Koeller, Carolina M, Guimaraes-Pinto, Kamila, Ribeiro-Gomes, Flavia L, Lopes, Marcela F, Heise, Norton, Freire-de-Lima, Celio G, Nunes, Marise P, DosReis, George A

“…We investigated early cellular responses induced by infection with Leishmania major in macrophages from resistant C57/BL6 mice. Infection increased production…”
Get full text