Search Results - "Filandr, František"
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Utilization of Fast Photochemical Oxidation of Proteins and Both Bottom-up and Top-down Mass Spectrometry for Structural Characterization of a Transcription Factor–dsDNA Complex
Published in Analytical chemistry (Washington) (22-02-2022)“…A combination of covalent labeling techniques and mass spectrometry (MS) is currently a progressive approach for deriving insights related to the mapping of…”
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Photoinduced damage of AsLOV2 domain is accompanied by increased singlet oxygen production due to flavin dissociation
Published in Scientific reports (05-03-2020)“…Flavin mononucleotide (FMN) belongs to the group of very efficient endogenous photosensitizers producing singlet oxygen, 1 O 2 , but with limited ability to be…”
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Author Correction: Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology
Published in Nature communications (02-04-2024)Get full text
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Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology
Published in Nature communications (11-03-2024)“…We present a hydrogen/deuterium exchange workflow coupled to tandem mass spectrometry (HX-MS 2 ) that supports the acquisition of peptide fragment ions…”
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Structural Dynamics of Lytic Polysaccharide Monooxygenase during Catalysis
Published in Biomolecules (Basel, Switzerland) (05-02-2020)“…Lytic polysaccharide monooxygenases (LPMOs) are industrially important oxidoreductases employed in lignocellulose saccharification. Using advanced…”
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The H2O2-dependent activity of a fungal lytic polysaccharide monooxygenase investigated with a turbidimetric assay
Published in Biotechnology for biofuels (05-03-2020)“…Abstract Background Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent redox enzymes that cleave recalcitrant biopolymers such as cellulose,…”
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14‐3‐3 protein binding blocks the dimerization interface of caspase‐2
Published in The FEBS journal (01-08-2020)“…Among all species, caspase‐2 (C2) is the most evolutionarily conserved caspase required for effective initiation of apoptosis following death stimuli. C2 is…”
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Molecular Basis of 14‐3‐3 Protein Dependent Regulation of Caspase‐2
Published in The FASEB journal (01-04-2020)“…Abstract only Among all species, caspase‐2 (C2) is the most evolutionarily conserved caspase required for effective initiation of apoptosis following death…”
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Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity
Published in Nucleic acids research (13-10-2023)“…Abstract Polymerase theta (Polθ) acts in DNA replication and repair, and its inhibition is synthetic lethal in BRCA1 and BRCA2-deficient tumor cells…”
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Chimeric Cellobiose Dehydrogenases Reveal the Function of Cytochrome Domain Mobility for the Electron Transfer to Lytic Polysaccharide Monooxygenase
Published in ACS catalysis (15-01-2021)“…The natural function of cellobiose dehydrogenase (CDH) to donate electrons from its catalytic flavodehydrogenase (DH) domain via its cytochrome (CYT) domain to…”
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The H 2 O 2 -dependent activity of a fungal lytic polysaccharide monooxygenase investigated with a turbidimetric assay
Published in Biotechnology for biofuels (2020)“…Lytic polysaccharide monooxygenases (LPMOs) are copper-dependent redox enzymes that cleave recalcitrant biopolymers such as cellulose, chitin, starch and…”
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