Search Results - "Filali, Liza"

How natural killer cells avoid self-destruction when killing their targets by Wurzer, Hannah, Filali, Liza, Thomas, Clément

“…How cytotoxic lymphocytes are protected against their own weapons during close combat with diseased target cells is an important and long-standing question in…”
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Actin cytoskeleton remodeling at the cancer cell side of the immunological synapse: good, bad, or both? by Ockfen, Elena, Filali, Liza, Pereira Fernandes, Diogo, Hoffmann, Céline, Thomas, Clément

“…Cytotoxic lymphocytes (CLs), specifically cytotoxic T lymphocytes and natural killer cells, are indispensable guardians of the immune system and orchestrate…”
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Is the tumor cell side of the immunological synapse a polarized secretory domain? by Biolato, Andrea Michela, Filali, Liza, Pereira Fernandes, Diogo, Moreau, Flora, Mgrditchian, Takouhie, Hoffmann, Céline, Thomas, Clément

“…The formation of a lytic immunological synapse (IS) is crucial for cytotoxic lymphocytes to accurately target and effectively eliminate malignant cells. While…”
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An integrated workflow for phosphopeptide identification in natural killer cells (NK-92MI) and their targets (MDA-MB-231) during immunological synapse formation by Perez-Hernandez, Daniel, Filali, Liza, Thomas, Clement, Dittmar, Gunnar

“…Here, we present a protocol to identify and quantify phosphopeptides during the dynamic formation of an immunological synapse. We describe steps for mixing…”
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Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome In Vitro by Pharmacological Inhibition of Cdc42-Induced Actin Cytoskeleton Remodeling by Wurzer, Hannah, Filali, Liza, Hoffmann, Céline, Krecke, Max, Biolato, Andrea Michela, Mastio, Jérôme, De Wilde, Sigrid, François, Jean Hugues, Largeot, Anne, Berchem, Guy, Paggetti, Jérôme, Moussay, Etienne, Thomas, Clément

“…Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia…”
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Actin cytoskeleton depolymerization increases matrix metalloproteinase gene expression in breast cancer cells by promoting translocation of cysteine-rich protein 2 to the nucleus by Mgrditchian, Takouhie, Brown-Clay, Joshua, Hoffmann, Céline, Müller, Tanja, Filali, Liza, Ockfen, Elena, Mao, Xianqing, Moreau, Flora, Casellas, Carla Pou, Kaoma, Tony, Mittelbronn, Michel, Thomas, Clément

“…The actin cytoskeleton plays a critical role in cancer cell invasion and metastasis; however, the coordination of its multiple functions remains unclear. Actin…”
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How natural killer cells avoid self-destruction when killing their targets by Hannah Wurzer, Liza Filali, Clément Thomas

“…How cytotoxic lymphocytes are protected against their own weapons during close combat with diseased target cells is an important and long-standing question in…”
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Measuring CTL Lytic Granule Secretion and Target Cell Membrane Repair by Fluorescent Lipophilic Dye Uptake at the Lytic Synapse by Müller, Sabina, Filali, Liza, Puissegur, Marie-Pierre, Valitutti, Salvatore

“…CD8 cytotoxic T lymphocytes (CTL) play a key role in anti-tumor immune response. They are therefore at the heart of current immunotherapy protocols against…”
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Actin remodeling and vesicular trafficking at the tumor cell side of the immunological synapse direct evasion from cytotoxic lymphocytes by Biolato, Andrea Michela, Filali, Liza, Wurzer, Hannah, Hoffmann, Céline, Gargiulo, Ernesto, Valitutti, Salvatore, Thomas, Clément

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Abstract 6439: Actin remodeling, inhibitory ligand polarization and small vesicle recruitment hinder effective anti-tumor immunity by shaping the tumor cell side of the immune synapse by Biolato, Andrea Michela, Filali, Liza, Hoffmann, Céline, Kleine-Borgmann, Felix, Ockfen, Elena, Krecke, Max, Mittelbronn, Michel, Thomas, Clément

“…Abstract Cancer immune evasion is a major obstacle to effective anticancer immunotherapies. Recently, we unveiled a mechanism crucial in cancer escape from…”
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Ultrarapid lytic granule release from CTLs activates Ca2+-dependent synaptic resistance pathways in melanoma cells by Filali, Liza, Puissegur, Marie-Pierre, Cortacero, Kevin, Cussat-Blanc, Sylvain, Khazen, Roxana, Van Acker, Nathalie, Frenois, François-Xavier, Abreu, Arnaud, Lamant, Laurence, Meyer, Nicolas, Vergier, Béatrice, Müller, Sabina, McKenzie, Brienne, Valitutti, Salvatore

“…Human cytotoxic T lymphocytes (CTLs) exhibit ultrarapid lytic granule secretion, but whether melanoma cells mobilize defense mechanisms with commensurate…”
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Ultrarapid lytic granule release from CTLs activates Ca 2+ -dependent synaptic resistance pathways in melanoma cells by Filali, Liza, Puissegur, Marie-Pierre, Cortacero, Kevin, Cussat-Blanc, Sylvain, Khazen, Roxana, Van Acker, Nathalie, Frenois, François-Xavier, Abreu, Arnaud, Lamant, Laurence, Meyer, Nicolas, Vergier, Béatrice, Müller, Sabina, McKenzie, Brienne, Valitutti, Salvatore

“…Human cytotoxic T lymphocytes (CTLs) exhibit ultrarapid lytic granule secretion, but whether melanoma cells mobilize defense mechanisms with commensurate…”
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