Search Results - "Figueiredo, Marcio Azevedo"
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Fluorescent transgenic zebrafish as a biosensor for growth-related effects of methyl parathion
Published in Aquatic toxicology (01-07-2014)“…•Fluorescent zebrafish was evaluated as a biosensor for pesticide effects on growth.•Methyl parathion decreases zebrafish growth in a concentration-dependent…”
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Growth hormone transgenesis affects osmoregulation and energy metabolism in zebrafish (Danio rerio)
Published in Transgenic research (01-02-2013)“…Growth hormone (GH) transgenic fish are at a critical step for possible approval for commercialization. Since this hormone is related to salinity tolerance in…”
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Improving the production of transgenic fish germlines: in vivo evaluation of mosaicism in zebrafish (Danio rerio) using a green fluorescent protein (GFP) and growth hormone cDNA transgene co-injection strategy
Published in Genetics and molecular biology (2007)“…In fish, microinjection is the method most frequently used for gene transfer. However, due to delayed transgene integration this technique almost invariably…”
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4
Food intake and appetite control in a GH-transgenic zebrafish
Published in Fish physiology and biochemistry (01-10-2015)“…The biological actions of growth hormone (GH) are pleiotropic, including growth promotion, energy mobilization, gonadal development, appetite, and social…”
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Muscle-specific growth hormone receptor (GHR) overexpression induces hyperplasia but not hypertrophy in transgenic zebrafish
Published in Transgenic research (01-06-2012)“…Even though growth hormone (GH) transgenesis has demonstrated potential for improved growth of commercially important species, the hormone excess may result in…”
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The effect of GH overexpression on GHR and IGF-I gene regulation in different genotypes of GH-transgenic zebrafish
Published in Comparative biochemistry and physiology. Part D, Genomics & proteomics (01-09-2007)“…Most biological actions of growth hormone (GH) are mediated by the insulin-like growth factor I (IGF-I) that is produced after the interaction of the hormone…”
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GH overexpression modifies muscle expression of anti-oxidant enzymes and increases spinal curvature of old zebrafish
Published in Experimental gerontology (01-06-2010)“…Growth hormone (GH) excess causes an increment in the metabolic rate and in reactive oxygen species generation, which accelerate the ageing process in mammals…”
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GH indirectly enhances the regeneration of transgenic zebrafish fins through IGF2a and IGF2b
Published in Transgenic research (01-10-2016)“…The somatotropic axis, composed essentially of the growth hormone (GH) and insulin-like growth factors (IGFs), is the main regulator of somatic growth in…”
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SOCS1 and SOCS3 are the main negative modulators of the somatotrophic axis in liver of homozygous GH-transgenic zebrafish ( Danio rerio )
Published in General and comparative endocrinology (01-03-2009)“…Abstract Homozygote individuals (HO) of the GH-transgenic zebrafish lineage (F0104), despite expressing double the amount of growth hormone (GH) in relation to…”
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Expression profile of IGF paralog genes in liver and muscle of a GH-transgenic zebrafish
Published in General and comparative endocrinology (15-01-2016)“…Highlights • GH-transgenesis induces high levels of IGFs transcription in zebrafish liver. • Transgenic zebrafish muscle seems to respond negatively to excess…”
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11
Expression profile of glucose transport-related genes under chronic and acute exposure to growth hormone in zebrafish
Published in Comparative biochemistry and physiology. Part A, Molecular & integrative physiology (01-07-2018)“…The brain is a highly demanding organ in terms of energy requirements, and precise regulatory mechanisms must operate to ensure adequate energy delivery to…”
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OCT4 mutations in human erythroleukemic cells: implications for multiple drug resistance (MDR) phenotype
Published in Molecular and cellular biochemistry (01-02-2015)“…The OCT4 transcription factor is a crucial stem cells marker and it has been related to the cancer stem cells concept. Moreover, it has also been associated to…”
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Effects of somatotrophic axis (GH/GHR) double transgenesis on structural and molecular aspects of the zebrafish immune system
Published in Fish & shellfish immunology (01-08-2015)“…The development of growth hormone (GH) transgenic fish has been shown to be a promising method to improve growth rates. However, the role of GH is not…”
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Effects of Double Transgenesis of Somatotrophic Axis (GH/GHR) on Skeletal Muscle Growth of Zebrafish (Danio rerio)
Published in Zebrafish (01-12-2015)“…Transgenic fish for growth hormone (GH) has been considered as a potential technological improvement in aquaculture. In this study, a double-transgenic…”
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Gene expression level: is it an important factor in codon optimization for overexpression of recombinant proteins?
Published in BMC proceedings (01-10-2014)“…Doc number: P224…”
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