Search Results - "Figueiredo, Isis M."

Highly functionalized piperidines: Free radical scavenging, anticancer activity, DNA interaction and correlation with biological activity by Das, Suvankar, da Silva, Cristiane J., Silva, Marina de M., Dantas, Maria Dayanne de A., de Fátima, Ângelo, Góis Ruiz, Ana Lúcia T., da Silva, Cleiton M., de Carvalho, João Ernesto, Santos, Josué C.C., Figueiredo, Isis M., da Silva-Júnior, Edeildo F., de Aquino, Thiago M., de Araújo-Júnior, João X., Brahmachari, Goutam, Modolo, Luzia Valentina

“…[Display omitted] Twenty-five piperidines were studied as potential radical scavengers and antitumor agents. Quantitative interaction of compounds with ctDNA…”
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Thimerosal changes protein conformation and increase the rate of fibrillation in physiological conditions: Spectroscopic studies using bovine serum albumin (BSA) by Santos, João César N., da Silva, Isabella M., Braga, Taniris C., de Fátima, Ângelo, Figueiredo, Isis M., Santos, Josué Carinhanha Caldas

“…The interaction between bovine serum albumin (BSA) and thimerosal (TM), an organomercury compound widely employed as a preservative in vaccines, was…”
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Interactions of tetracyclines with ovalbumin, the main allergen protein from egg white: Spectroscopic and electrophoretic studies by Dantas, Maria Dayanne de A., Tenório, Humberto de Araújo, Lopes, Thiago Inácio B., Pereira, Hugo Juarez V., Marsaioli, Anita J., Figueiredo, Isis M., Santos, Josué Carinhanha Caldas

“…[Display omitted] •For the first time, the interaction between tetracyclines and ovalbumin is reported.•The magnitude of the interaction process followed the…”
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Studies on free radical scavenging, cancer cell antiproliferation, and calf thymus DNA interaction of Schiff bases by da Silva, Cleiton M., Silva, Marina M., Reis, Fabiano S., Ruiz, Ana Lúcia T.G., de Carvalho, João E., Santos, Josué C.C., Figueiredo, Isis M., Alves, Rosemeire B., Modolo, Luzia V., de Fátima, Ângelo

“…Thirty-nine Schiff bases were synthesized by performing microwave-assisted condensation of the corresponding aldehydes and aromatic amines. Their reactive…”
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Interaction between bioactive compound 11a-N-tosyl-5-deoxi-pterocarpan (LQB-223) and Calf thymus DNA: Spectroscopic approach, electrophoresis and theoretical studies by Silva, Marina M., Nascimento, Eduarda O.O., Silva, Edeíldo F., Araújo, João Xavier de, Santana, Camilla C., Grillo, Luciano Aparecido M., de Oliveira, Rafaela S., R.R.Costa, Paulo, Buarque, Camilla D., Santos, Josué Carinhanha C., Figueiredo, Isis M.

“…The interaction of small molecules with DNA has been quite important, since this biomolecule is currently the major target for a wide range of drugs in…”
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Consequences of thimerosal on human erythrocyte hemoglobin: Assessing functional and structural protein changes induced by an organic mercury compound by Sales, Marcos V.S., da Silva Filho, Reginaldo C., Silva, Marina M., Rocha, Jeanynne L., Freire, Ricardo O., de L. Tanabe, Eloiza Lopes, Silva, Elaine C.O., Fonseca, Eduardo Jorge S., Figueiredo, Isis M., Rocha, Ueslen, Santos, Josué Carinhanha C., Leite, Ana Catarina R.

“…[Display omitted] •Thimerosal damages the structure of hemoglobin inducing the loss of its main function as O2 transporter.•Raman indicates that thimerosal…”
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Interactions of tetracyclines with milk allergenic protein (casein): a molecular and biological approach by Dantas, Maria Dayanne de A., Silva, Marina de Magalhães, Silva, Osmar Nascimento, Franco, Octavio Luiz, Fensterseifer, Isabel Cristina Marques, Tenório, Humberto de Araújo, Pereira, Hugo Juarez V., Figueiredo, Isis M., Santos, Josué Carinhanha C.

“…Tetracycline (TC), oxytetracycline (OTC), and chlortetracycline (CTC) interactions with the allergenic milk protein casein (CAS) were here evaluated simulating…”
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Evaluation of guanylhydrazone derivatives as inhibitors of Candida rugosa digestive lipase: Biological, biophysical, theoretical studies and biotechnological application by Santana, Camilla C., Silva-Júnior, Edeíldo F., Santos, João César N., Rodrigues, Érica E. da S., da Silva, Isabella M., Araújo-Júnior, João X., do Nascimento, Ticiano G., Oliveira Barbosa, Leandro A., Dornelas, Camila B., Figueiredo, Isis M., Santos, Josué Carinhanha C., Grillo, Luciano Aparecido M.

“…[Display omitted] •Five guanylhydrazone derivatives were evaluated as lipase inhibitors in vitro.•The derivative LQM11 was the most active with IC50 of…”
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1H NMR, a Rapid Method to Monitor Organic Acids during Cupuassu (Theobroma grandiflorum Spreng) Processing by Figueiredo, Isis M, Pereira, Nadia R, Efraim, Priscilla, García, Nelson H. P, Rodrigues, Nadia R, Marsaioli, Antônio, Marsaioli, Anita J

“…The development of an analytical method using 1H nuclear magnetic resonance (1H NMR) spectrometry to monitor cupuassu (Theobroma grandiflorum Spreng) bean…”
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Aminoguanidine Hydrazone Derivatives: The Antioxidant, Antineoplastic Profile, and Interaction with ctDNA Studies by Guimarães, Ari, Oliveira, Woodland, Araújo, Aline, Foglio, Mary Ann, Aquino, Pedro, de Araújo-Júnior, João, Schmitt, Martine, Ruiz, Ana Lúcia, Figueiredo, Isis, Santos, Josué

“…Herein, we report the synthesis and evaluation of four aminoguanidine hydrazone derivatives with different aromatic moieties. This class of compounds presents…”
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2-(Pyridin-4yl)benzothiazole and Its Benzimidazole-Analogue: Biophysical and in silico Studies on Their Interaction with Urease and in vitro Anti-Helicobacter pylori Activities by Pereira, Camila, de Lyra, Ana, Oliveira, Breno, Nascimento, Igor, da Silva-Júnior, Edeildo, de Aquino, Thiago, Sisto, Francesca, Figueiredo, Isis, Martins, Felipe, Modolo, Luzia, Santos, Josué, de Fátima, Ângelo

“…In this study, the interaction between benzothiazole (BTA, concentration of a drug required for 50% inhibition in vitro (IC50) = 0.77 mM) and benzimidazole…”
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Correlation between DNA/HSA-interactions and antimalarial activity of acridine derivatives: Proposing a possible mechanism of action by de M. Silva, Marina, Macedo, Taís S., Teixeira, Helena Mariana P., Moreira, Diogo Rodrigo M., Soares, Milena B.P., da C. Pereira, Ana Ligia, de L. Serafim, Vanessa, Mendonça-Júnior, Francisco J.B., do Carmo A. de Lima, Maria, de Moura, Ricardo O., da Silva-Júnior, Edeildo F., de Araújo-Júnior, João Xavier, de A. Dantas, Maria Dayanne, de O. O. Nascimento, Eduarda, Maciel, Thamilla Maria S., de Aquino, Thiago Mendonça, Figueiredo, Isis M., Santos, Josué C.C.

“…Acridines are considered an important class of compounds due to their wide variety of biological activities. In this work, we synthesized four acridine…”
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Interaction of β-Carbolines with DNA: Spectroscopic Studies, Correlation with Biological Activity and Molecular Docking by Silva, Marina M., Savariz, Franciele C., Silva-Júnior, Edeíldo F., Aquino, Thiago M. de, Sarragiotto, Maria Helena, Santos, Josué C. C., Figueiredo, Isis M.

“…Quantitative interaction of twelve β-carboline derivatives with calf thymus deoxyribonucleic acid (ctDNA) using spectroscopic techniques was evaluated. The…”
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Annonalide and derivatives: Semisynthesis, cytotoxic activities and studies on interaction of annonalide with DNA by Marques, Ricardo A., Gomes, Akenaton O.C.V., de Brito, Maria V., dos Santos, Ana L.P., da Silva, Gladyane S., de Lima, Leandro B., Nunes, Fátima M., de Mattos, Marcos C., de Oliveira, Fátima C.E., do Ó Pessoa, Cláudia, de Moraes, Manoel O., de Fátima, Ângelo, Franco, Lucas L., Silva, Marina de M., Dantas, Maria Dayanne de A., Santos, Josué C.C., Figueiredo, Isis M., da Silva-Júnior, Edeíldo F., de Aquino, Thiago M., de Araújo-Júnior, João X., de Oliveira, Maria C.F., Leslie Gunatilaka, A.A.

“…The cytotoxic activity of the pimarane diterpene annonalide (1) and nine of its semisynthetic derivatives (2–10) was investigated against the human tumor cell…”
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Oncocalyxone A: electrochemical, spectroscopic investigation and studies of its interaction with DNA, nucleobases and N-acetylcysteine by Costa, Cicero de O., Costa, Erivaldo de O., Ferreira, Fabrícia da R., Viana, Luciana da S., Silva, Leonardo V. da, Silva, Francisco de A. dos Santos, Abreu, Fabiane C. de, Figueiredo, Isis M., Pinho Jr, Waldomiro, Bento, Edson de S., Lemos, Telma L. G., Pessoa, Otília D. L., Aguilera-Venegas, Benjamin, Norambuena, Ester, Olea-Azar, Claudio, Goulart, Marília O. F.

“…The formation of paramagnetic species from oncocalyxone A in aprotic medium was confirmed by performing in situ electrochemical-electron spin resonance (E-ESR)…”
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1 H NMR, a Rapid Method to Monitor Organic Acids during Cupuassu ( Theobroma grandiflorum Spreng) Processing by Figueiredo, Isis M., Pereira, Nadia R., Efraim, Priscilla, García, Nelson H. P., Rodrigues, Nadia R., Marsaioli, Antônio, Marsaioli, Anita J.

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Synthesis and antiproliferative activity of novel limonene derivatives with a substituted thiourea moiety by Figueiredo, Isis M., Santos, Luciane V. dos, Costa, Willian F. da, Carvalho, João E. de, Silva, Cleuza C. da, Sacoman, Juliana L., Kohn, Luciana K., Sarragiotto, Maria H.

“…A series of R-(+)-limonene derivatives bearing a substituted thiourea moiety (3-13) and five S-methyl analogs (14-18) were synthesized and evaluated for their…”
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