Search Results - "Figueira, Juan Carlos"
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A standardized clinical database for research in Chagas disease: The NHEPACHA network
Published in PLoS neglected tropical diseases (15-08-2024)“…The NHEPACHA Iberoamerican Network, founded on the initiative of a group of researchers from Latin American countries and Spain, aims to establish a research…”
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Identification of compounds with activity against Trypanosoma cruzi within a collection of synthetic nucleoside analogs
Published in Frontiers in cellular and infection microbiology (13-01-2023)“…Chagas disease is caused by the protozoan parasite , and it is the most important neglected tropical disease in the Americas. Two drugs are available to treat…”
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Topical repellents for malaria prevention
Published in Cochrane database of systematic reviews (21-08-2023)“…Insecticide-based interventions, such as long-lasting insecticide-treated nets (LLINs) and indoor residual spraying (IRS), remain the backbone of malaria…”
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Influenza A pandemic (H1N1) 2009 virus and HIV
Published in Emerging infectious diseases (01-07-2010)Get full text
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Transcriptomic evidence of immune modulation in subjects with chronic Trypanosoma cruzi infection
Published in The Journal of infectious diseases (28-08-2024)“…Chagas disease is a neglected tropical infection that affects millions of people. This study explores transcriptomic changes in T. cruzi-infected subjects…”
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Quality assurance of serologic testing for Chagas disease in a primary care setting of rural Paraguay
Published in Acta tropica (01-11-2024)“…•ELISA kits to detect T. cruzi in different settings showed good agreement.•Performance of ELISA kits in rural areas could be affected by operator…”
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A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protocol for a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (05-08-2020)“…• Primary objective: to evaluate the effect of intravenous melatonin (IVM) on mortality in adult patients admitted to the intensive care unit (ICU) with…”
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A guide for the generation of repositories of clinical samples for research on Chagas disease
Published in PLoS neglected tropical diseases (15-08-2024)“…Chagas disease, caused by the parasite Trypanosoma cruzi, affects over 6 million people, mainly in Latin America. Two different clinical phases, acute and…”
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Early Tracheostomy for Managing ICU Capacity During the COVID-19 Outbreak
Published in Chest (01-01-2022)“…During the first wave of the COVID-19 pandemic, shortages of ventilators and ICU beds overwhelmed health care systems. Whether early tracheostomy reduces the…”
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Long-term survival of mechanically ventilated patients with severe COVID-19: an observational cohort study
Published in Annals of intensive care (02-10-2021)“…Background Information is lacking regarding long-term survival and predictive factors for mortality in patients with acute hypoxemic respiratory failure due to…”
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Cooperation for malaria control and elimination in the Guiana Shield
Published in The Lancet global health (01-05-2024)“…The Guiana Shield, a small region of South America, is currently one of the main hotspots of malaria transmission on the continent. This Amazonian area is…”
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State-of-the-Art in the Drug Discovery Pathway for Chagas Disease: A Framework for Drug Development and Target Validation
Published in Research and reports in tropical medicine (30-06-2023)“…Chagas disease is the most important protozoan infection in the Americas, and constitutes a significant public health concern throughout the world. Development…”
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Impact of Remdesivir on the Treatment of COVID-19 During the First Wave in Spain
Published in Advances in therapy (01-07-2021)“…Introduction Spain was one of the most affected countries during the first wave of COVID-19, having the highest mortality rate in Europe. The aim of this…”
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Changes in lipid abundance are associated with disease progression and treatment response in chronic Trypanosoma cruzi infection
Published in Parasites & vectors (09-11-2024)“…Chagas disease, caused by the parasite Trypanosoma cruzi, is a zoonosis that affects more than seven million people. Current limitations on the diagnosis of…”
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Digital acoustic surveillance for early detection of respiratory disease outbreaks in Spain: a protocol for an observational study
Published in BMJ open (02-07-2021)“…IntroductionCough is a common symptom of COVID-19 and other respiratory illnesses. However, objectively measuring its frequency and evolution is hindered by…”
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Performance evaluation of human cough annotators: optimal metrics and sex differences
Published in BMJ open respiratory research (01-11-2023)“…IntroductionDespite its high prevalence and significance, there is still no widely available method to quantify cough. In order to demonstrate agreement with…”
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Development and Application of an Assay to Evaluate the Anti-Parasitic Effect of Humoral Responses against Trypanosoma cruzi
Published in Microorganisms (Basel) (18-01-2023)“…Mounting a balanced and robust humoral immune response is of utmost importance for reducing the infectivity of . While the role of such a response in…”
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Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial
Published in The lancet respiratory medicine (01-05-2021)“…Elevated proinflammatory cytokines are associated with greater COVID-19 severity. We aimed to assess safety and efficacy of sarilumab, an interleukin-6…”
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A Cohort of Patients with COVID-19 in a Major Teaching Hospital in Europe
Published in Journal of clinical medicine (04-06-2020)“…Background: Since the confirmation of the first patient infected with SARS-CoV-2 in Spain in January 2020, the epidemic has grown rapidly, with the greatest…”
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