Search Results - "Figaji, Anthony"

Anatomical and Physiological Differences between Children and Adults Relevant to Traumatic Brain Injury and the Implications for Clinical Assessment and Care by Figaji, Anthony A

“…General and central nervous system anatomy and physiology in children is different to that of adults and this is relevant to traumatic brain injury (TBI) and…”
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The pathogenesis of tuberculous meningitis by Davis, Angharad Grace, Rohlwink, Ursula Karin, Proust, Alizé, Figaji, Anthony A., Wilkinson, Robert J.

“…Tuberculosis (TB) remains a leading cause of death globally. Dissemination of TB to the brain results in the most severe form of extrapulmonary TB, tuberculous…”
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A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC) by Chesnut, Randall, Aguilera, Sergio, Buki, Andras, Bulger, Eileen, Citerio, Giuseppe, Cooper, D. Jamie, Arrastia, Ramon Diaz, Diringer, Michael, Figaji, Anthony, Gao, Guoyi, Geocadin, Romer, Ghajar, Jamshid, Harris, Odette, Hoffer, Alan, Hutchinson, Peter, Joseph, Mathew, Kitagawa, Ryan, Manley, Geoffrey, Mayer, Stephan, Menon, David K., Meyfroidt, Geert, Michael, Daniel B., Oddo, Mauro, Okonkwo, David, Patel, Mayur, Robertson, Claudia, Rosenfeld, Jeffrey V., Rubiano, Andres M., Sahuquillo, Juan, Servadei, Franco, Shutter, Lori, Stein, Deborah, Stocchetti, Nino, Taccone, Fabio Silvio, Timmons, Shelly, Tsai, Eve, Ullman, Jamie S., Vespa, Paul, Videtta, Walter, Wright, David W., Zammit, Christopher, Hawryluk, Gregory W. J.

“…Background Current guidelines for the treatment of adult severe traumatic brain injury (sTBI) consist of high-quality evidence reports, but they are no longer…”
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Metabolite transport across central nervous system barriers by Carstens, Gesa, Verbeek, Marcel M, Rohlwink, Ursula K, Figaji, Anthony A, te Brake, Lindsey, van Laarhoven, Arjan

“…Metabolomic analysis of cerebrospinal fluid (CSF) is used to improve diagnostics and pathophysiological understanding of neurological diseases. Alterations in…”
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Pediatric head injury—an opportunity to make a difference in the global burden of disease by Figaji, Anthony A.

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Biomarkers of Cerebral Injury and Inflammation in Pediatric Tuberculous Meningitis by Rohlwink, Ursula K., Mauff, Katya, Wilkinson, Katalin A., Enslin, Nico, Wegoye, Emmanuel, Wilkinson, Robert J., Figaji, Anthony A.

“…Background. Tuberculous meningitis (TBM) leads to death or disability in half the affected individuals. Tools to assess severity and predict outcome are…”
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Imaging Features of the Brain, Cerebral Vessels and Spine in Pediatric Tuberculous Meningitis With Associated Hydrocephalus by Rohlwink, Ursula K, Kilborn, Tracy, Wieselthaler, Nicky, Banderker, Ebrahim, Zwane, Eugene, Figaji, Anthony A

“…BACKGROUND:Pediatric tuberculous meningitis (TBM) leads to high rates of mortality and morbidity. Prompt diagnosis and initiation of treatment are challenging;…”
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Cerebrovascular Pressure Reactivity Has a Strong and Independent Association With Outcome in Children With Severe Traumatic Brain Injury by Smith, Claudia A., Rohlwink, Ursula K., Mauff, Katya, Thango, Nqobile S., Hina, Thembani S., Salie, Shamiel, Enslin, Johannes M. N., Figaji, Anthony A.

“…To examine cerebrovascular pressure reactivity index (PRx) in a large cohort of children with severe traumatic brain injury (sTBI) in association with…”
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Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care by Le Roux, Peter, Menon, David K, Citerio, Giuseppe, Vespa, Paul, Bader, Mary Kay, Brophy, Gretchen M, Diringer, Michael N

“…Neurocritical care depends, in part, on careful patient monitoring but as yet there are little data on what processes are the most important to monitor, how…”
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Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity by Rohlwink, Ursula K., Figaji, Anthony, Wilkinson, Katalin A., Horswell, Stuart, Sesay, Abdul K., Deffur, Armin, Enslin, Nico, Solomons, Regan, Van Toorn, Ronald, Eley, Brian, Levin, Michael, Wilkinson, Robert J., Lai, Rachel P. J.

“…Tuberculous meningitis (TBM) is the most severe form of TB with high rates of mortality and morbidity. Here we conduct RNA-sequencing on whole blood as well as…”
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Biomarkers of brain injury in cerebral infections by Rohlwink, Ursula K, Figaji, Anthony A

“…Central nervous system (CNS) infections present a major burden of disease worldwide and are associated with high rates of mortality and morbidity. Swift…”
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A pilot study of inflammatory mediators in brain extracellular fluid in paediatric TBM by Loxton, Nicholas W, Rohlwink, Ursula K, Tshavhungwe, Mvuwo, Dlamini, Lindizwe, Shey, Muki, Enslin, Nico, Figaji, Anthony

“…Tuberculous meningitis (TBM) is the most fatal form of tuberculosis and frequently occurs in children. The inflammatory process initiates secondary brain…”
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What is next in African neuroscience? by Donald, Kirsten A, Maina, Mahmoud, Patel, Nilesh, Nguemeni, Carine, Mohammed, Wael, Abubakar, Amina, Brown, Matthew, Stoyanova, Raliza, Welchman, Andrew, Walker, Natasha, Willett, Alexis, Kariuki, Symon M, Figaji, Anthony, Stein, Dan J, Ihunwo, Amadi O, Daniels, William, Newton, Charles R

“…Working in Africa provides neuroscientists with opportunities that are not available in other continents. Populations in this region exhibit the greatest…”
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Neurotrauma clinicians' perspectives on the contextual challenges associated with traumatic brain injury follow up in low-income and middle-income countries: A reflexive thematic analysis by Brandon G Smith, Charlotte J Whiffin, Ignatius N Esene, Claire Karekezi, Tom Bashford, Muhammad Mukhtar Khan, Davi J Fontoura Solla, Bhagavatula Indira Devi, Wellingson S Paiva, Franco Servadei, Peter J Hutchinson, Angelos G Kolias, Anthony Figaji, Andres M Rubiano

“…BackgroundTraumatic brain injury (TBI) is a major global health issue, but low- and middle-income countries (LMICs) face the greatest burden. Significant…”
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Clinical characteristics and neurodevelopmental outcomes of children with tuberculous meningitis and hydrocephalus by Rohlwink, Ursula K, Donald, Kirsty, Gavine, Bronwyn, Padayachy, Llewellyn, Wilmshurst, Jo M, Fieggen, Graham A, Figaji, Anthony A

“…Aim Tuberculous meningitis (TBM) is a lethal and commonly occurring form of extra‐pulmonary tuberculosis in children, often complicated by hydrocephalus which…”
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Management of Spasticity After Traumatic Brain Injury in Children by Enslin, Johannes M N, Rohlwink, Ursula K, Figaji, Anthony

“…Traumatic brain injury is a common cause of disability worldwide. In fact, trauma is the second most common cause of death and disability, still today…”
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The neurosurgical and acute care management of tuberculous meningitis: Evidence and current practice by Figaji, Anthony A, Fieggen, A. Graham

“…Summary Tuberculous meningitis (TBM) is the most lethal form of tuberculosis; mortality is high and survivors are often left neurologically disabled. Several…”
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Neurosurgeons’ experiences of conducting and disseminating clinical research in low-income and middle-income countries: a reflexive thematic analysis by Whiffin, Charlotte Jane, Smith, Brandon George, Esene, Ignatius N, Karekezi, Claire, Bashford, Tom, Mukhtar Khan, Muhammad, Hutchinson, Peter John, Kolias, Angelos G, Fontoura Solla, Davi Jorge, Paiva, Wellingson S, Figaji, Anthony

“…ObjectivesLow-income and-middle-income countries (LMICs) are increasing investment in research and development, yet there remains a paucity of neurotrauma…”
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Neurotrauma clinicians’ perspectives on the contextual challenges associated with traumatic brain injury follow up in low-income and middle-income countries: A reflexive thematic analysis by Smith, Brandon G, Whiffin, Charlotte J, Esene, Ignatius N, Karekezi, Claire, Bashford, Tom, Mukhtar Khan, Muhammad, Fontoura Solla, Davi J, Indira Devi, Bhagavatula, Paiva, Wellingson S, Servadei, Franco, Hutchinson, Peter J, Kolias, Angelos G, Figaji, Anthony, Rubiano, Andres M

“…Background Traumatic brain injury (TBI) is a major global health issue, but low- and middle-income countries (LMICs) face the greatest burden. Significant…”
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Management and outcomes of myelomeningocele-associated hydrocephalus in low-income and middle-income countries: a systematic review and meta-analysis protocol by Takoutsing, Berjo Dongmo, Yanez Touzet, Alvaro, Park, Jay J, Lee, Seong Hoon, Bligh, Emily R, Egiz, Abdullah, Gillespie, Conor S, Figaji, Anthony

“…IntroductionHydrocephalus and myelomeningocele (MMC) place disproportionate burdens of disease on low-income and middle-income countries (LMICs)…”
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