Search Results - "Fields, Peter A"

Hot spots in cold adaptation: Localized increases in conformational flexibility in lactate dehydrogenase A4 orthologs of Antarctic notothenioid fishes by Fields, P A, Somero, G N

“…To elucidate mechanisms of enzymatic adaptation to extreme cold, we determined kinetic properties, thermal stabilities, and deduced amino acid sequences of…”
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Reductionism in the study of enzyme adaptation by Fields, Peter A.

“…One of the principal goals of comparative biology is the elucidation of mechanisms by which organisms adapt to different environments. The study of enzyme…”
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Adaptations of protein structure and function to temperature: there is more than one way to 'skin a cat' by Fields, Peter A, Dong, Yunwei, Meng, Xianliang, Somero, George N

“…Sensitivity to temperature helps determine the success of organisms in all habitats, and is caused by the susceptibility of biochemical processes, including…”
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A year in the salt marsh: Seasonal changes in gill protein expression in the temperate intertidal mussel Geukensia demissa by Fields, Peter A., Eraso, Ariel

“…Organisms living in temperate and polar regions experience extensive seasonal changes in the physical and biotic environment, including temperature,…”
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Proteomic responses of blue mussel (Mytilus) congeners to temperature acclimation by Fields, Peter A, Zuzow, Marcus J, Tomanek, Lars

“…The ability to acclimate to variable environmental conditions affects the biogeographic range of species, their success at colonizing new habitats, and their…”
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Proteomics: Protein Identification using Online Databases by Eurich, Chris, Fields, Peter A., Rice, Elizabeth

“…Proteomics is an emerging area of systems biology that allows simultaneous study of thousands of proteins expressed in cells, tissues, or whole organisms. We…”
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Changes in protein expression in the salt marsh mussel Geukensia demissa: evidence for a shift from anaerobic to aerobic metabolism during prolonged aerial exposure by Fields, Peter A, Eurich, Chris, Gao, William L, Cela, Bekim

“…During aerial exposure (emersion), most sessile intertidal invertebrates experience cellular stress caused by hypoxia, and the amount and types of…”
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Function of muscle-type lactate dehydrogenase and citrate synthase of the Galápagos marine iguana, Amblyrhynchus cristatus, in relation to temperature by Fields, Peter A., Strothers, Chad M., Mitchell, Mark A.

“…The Galápagos marine iguana, Amblyrhynchus cristatus, is unique among lizards in foraging subtidally, leading to activity across a broad range of ambient…”
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Review: Protein function at thermal extremes: balancing stability and flexibility by Fields, Peter A.

“…No organism can survive across the entire temperature range found in the biosphere, and a given species can rarely support active metabolism across more than a…”
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Rapid proteomic responses to a near-lethal heat stress in the salt marsh mussel Geukensia demissa by Fields, Peter A, Burmester, Elizabeth M, Cox, Kelly M, Karch, Kelly R

“…Acute heat stress perturbs cellular function on a variety of levels, leading to protein dysfunction and aggregation, oxidative stress and loss of metabolic…”
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Thermal stability and structure of glyceraldehyde-3-phosphate dehydrogenase from the coral Acropora millepora by Perez, Astrid M, Wolfe, Jacob A, Schermerhorn, Janse T, Qian, Yiwen, Cela, Bekim A, Kalinowski, Cody R, Largoza, Garrett E, Fields, Peter A, Brandt, Gabriel S

“…Corals are vulnerable to increasing ocean temperatures. It is known that elevated temperatures lead to the breakdown of an essential mutualistic relationship…”
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Latitudinal Variation in Protein Expression After Heat Stress in the Salt Marsh Mussel Geukensia demissa by Fields, Peter A, Cox, Kelly M, Karch, Kelly R

“…Individuals of a broadly distributed species often experience significantly different environmental conditions depending on location. For example, the mussel…”
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Temperature sensitivities of cytosolic malate dehydrogenases from native and invasive species of marine mussels (genus Mytilus): sequence-function linkages and correlations with biogeographic distribution by Fields, Peter A, Rudomin, Emily L, Somero, George N

“…The blue mussel Mytilus galloprovincialis, a native of the Mediterranean Sea, has invaded the west coast of North America in the past century, displacing the…”
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Decreases in activation energy and substrate affinity in cold-adapted A4-lactate dehydrogenase: evidence from the Antarctic notothenioid fish Chaenocephalus aceratus by Fields, Peter A, Houseman, Daniel E

“…Enzyme function is strongly affected by temperature, and orthologs from species adapted to different thermal environments often show temperature compensation…”
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High-Pressure–Low-Temperature Cryostat Designed for Use with Fourier Transform Infrared Spectrometers and Time-Resolved Infrared Spectroscopy by Calladine, James A., Love, Ashley, Fields, Peter A., Wilson, Richard G.M., George, Michael W.

“…The design for a new high-pressure–low-temperature infrared (IR) cell for performing experiments using conventional Fourier transform infrared or fast…”
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Coping with thermal challenges: physiological adaptations to environmental temperatures by Tattersall, Glenn J, Sinclair, Brent J, Withers, Philip C, Fields, Peter A, Seebacher, Frank, Cooper, Christine E, Maloney, Shane K

“…Temperature profoundly influences physiological responses in animals, primarily due to the effects on biochemical reaction rates. Since physiological responses…”
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Sublethal Exposure to UV Radiation Affects Respiration Rates of the Freshwater Cladoceran Daphnia catawba by Fischer, Janet M., Fields, Peter A., Pryzbylkowski, Peter G., Nicolai, Jaclyn L., Neale, Patrick J.

“…We examined the effects of UV radiation (UVR) on metabolic rates of the freshwater cladoceran Daphnia catawba. We exposed D. catawba to UVB for 12 h in a lamp…”
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Phylogenetic relationships and biochemical properties of the duplicated cytosolic and mitochondrial isoforms of malate dehydrogenase from a teleost fish, Sphyraena idiastes by Lin, Jen-Jen, Yang, Tzung-Horng, Wahlstrand, Benjamin D, Fields, Peter A, Somero, George N

“…Unlike birds and mammals, teleost fish express two paralogous isoforms (paralogues) of cytosolic malate dehydrogenase (cMDH; EC 1.1.1.37; NAD+: malate…”
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Structure and thermal stability of a coral metabolic enzyme by Wolfe, Jacob A, Qian, Yiwen, Perez, Astrid M, Schermerhorn, Janse T, Cela, Bekim, Kalinowski, Cody R, Largoza, Garrett E, Fields, Peter A, Brandt, Gabriel

“…Increased ocean temperatures can lead to coral bleaching, as the symbiotic relationship between coral and photosynthetic algae breaks down. The molecular…”
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Thermal stability and structure of glyceraldehyde-3-phosphate dehydrogenase from the coral by Perez, Astrid M, Wolfe, Jacob A, Schermerhorn, Janse T, Qian, Yiwen, Cela, Bekim A, Kalinowski, Cody R, Largoza, Garrett E, Fields, Peter A, Brandt, Gabriel S

“…Corals are vulnerable to increasing ocean temperatures. It is known that elevated temperatures lead to the breakdown of an essential mutualistic relationship…”
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