Search Results - "Field, K. J."

Phytophagy impacts the quality and quantity of plant carbon resources acquired by mutualistic arbuscular mycorrhizal fungi by Bell, C. A., Magkourilou, E., Ault, J. R., Urwin, P. E., Field, K. J.

“…Arbuscular mycorrhizal (AM) fungi associate with the roots of many plant species, enhancing their hosts access to soil nutrients whilst obtaining their carbon…”
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UK Lung Screen (UKLS) nodule management protocol: modelling of a single screen randomised controlled trial of low-dose CT screening for lung cancer by Baldwin, D R, Duffy, S W, Wald, N J, Page, R, Hansell, D M, Field, J K

“…The UK Lung Screen (UKLS) is a randomised controlled trial of the use of low-dose multidetector CT for lung cancer screening. It completed the Health…”
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The LLP risk model: an individual risk prediction model for lung cancer by Cassidy, A, Myles, J P, van Tongeren, M, Page, R D, Liloglou, T, Duffy, S W, Field, J K

“…Using a model-based approach, we estimated the probability that an individual, with a specified combination of risk factors, would develop lung cancer within a…”
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Translation of research results to simple estimates of the likely effect of a lung cancer screening programme in the United Kingdom by Duffy, S W, Field, J K, Allgood, P C, Seigneurin, A

“…Background: There is considerable interest in the possibility of provision of lung cancer screening services in many developed countries. There is, however, no…”
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The clinical determinants of malignant transformation in oral epithelial dysplasia by Ho, M.W, Risk, J.M, Woolgar, J.A, Field, E.A, Field, J.K, Steele, J.C, Rajlawat, B.P, Triantafyllou, A, Rogers, S.N, Lowe, D, Shaw, R.J

“…Summary Background While the size and clinical appearance are known risk factors for malignant transformation of potentially malignant oral the importance of…”
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Lung cancer screening: the way forward by Field, J K, Duffy, S W

“…To take lung cancer screening into national programmes, we first have to answer the question whether low-dose computed tomography (LDCT) screening and…”
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Comparison of discriminatory power and accuracy of three lung cancer risk models by D'Amelio, A M, Cassidy, A, Asomaning, K, Raji, O Y, Duffy, S W, Field, J K, Spitz, M R, Christiani, D, Etzel, C J

“…Background: Three lung cancer (LC) models have recently been constructed to predict an individual's absolute risk of LC within a defined period. Given their…”
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A systematic review of the characteristics associated with recall rates, detection rates and positive predictive values of computed tomography screening for lung cancer by Seigneurin, A., Field, J.K., Gachet, A., Duffy, S.W.

“…Low-dose computed tomography (LDCT) screening has been shown to reduce mortality from lung cancer but at a substantial cost in diagnostic activity. The…”
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A microRNA-based prediction algorithm for diagnosis of non-small lung cell carcinoma in minimal biopsy material by Bediaga, N G, Davies, M P A, Acha-Sagredo, A, Hyde, R, Raji, O Y, Page, R, Walshaw, M, Gosney, J, Alfirevic, A, Field, J K, Liloglou, T

“…Background: Diagnosis is jeopardised when limited biopsy material is available or histological quality compromised. Here we developed and validated a…”
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Cytoglobin is upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer by Shaw, R J, Omar, M M, Rokadiya, S, Kogera, F A, Lowe, D, Hall, G L, Woolgar, J A, Homer, J, Liloglou, T, Field, J K, Risk, J M

“…Background: Cytoglobin (Cygb) was first described in 2002 as an intracellular globin of unknown function. We have previously shown the downregulation of…”
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Promoter methylation of P16, RARβ, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing by Shaw, R J, Liloglou, T, Rogers, S N, Brown, J S, Vaughan, E D, Lowe, D, Field, J K, Risk, J M

“…Methylation profiling of cancer tissues has identified this mechanism as an important component of carcinogenesis. Epigenetic silencing of tumour suppressor…”
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Genetic aberrations in oral or head and neck squamous cell carcinoma (SCCHN): 1. Carcinogen metabolism, DNA repair and cell cycle control by Scully, C., Field, J.K., Tanzawa, H.

“…The ability to metabolise carcinogens or pro-carcinogens, repair DNA damage, and control cell signalling and the cell cycle are fundamental to homeostasis…”
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Unique volatolomic signatures of TP53 and KRAS in lung cells by DAVIES, M. P. A, BARASH, O, JERIES, R, PELED, N, ILOUZE, M, HYDE, R, MARCUS, M. W, FIELD, J. K, HAICK, H

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Genetic aberrations in oral or head and neck squamous cell carcinoma 2: chromosomal aberrations by Scully, C, Field, J.K, Tanzawa, H

“…Carcinogenesis is the result of a series of genetic mutations resulting in unregulated growth of a clone of cells and the development of malignant lesion that…”
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Smoking history and lung carcinoma: KRAS mutation is an early hit in lung adenocarcinoma development by Thunnissen, F.B, Prinsen, C, Hol, B, Van der Drift, M, Vesin, A, Brambilla, C, Montuenga, L, Field, J.K

“…Abstract Background In a European multicenter prospective study patients with lung cancer were interviewed for smoking history and biological samples centrally…”
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Expression of p53, pRB, and p16 in lung tumours: a validation study on tissue microarrays by Leversha, MA, Fielding, P, Watson, S, Gosney, JR, Field, JK

“…Tissue microarrays have been created from 326 lung tumours, including 173 squamous cell carcinomas (SCCs) and 132 adenocarcinomas (ADs). In order to evaluate…”
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METH-2 silencing and promoter hypermethylation in NSCLC by DUNN, J. R, PANUTSOPULOS, D, SHAW, M. W, HEIGHWAY, J, DORMER, R, SALMO, E. N, WATSON, S. G, FIELD, J. K, LILOGLOU, T

“…The antiangiogenic factor METH-2 (ADAMTS-8) was identified in a previous dual-channel cDNA microarray analysis to be at least two-fold under-represented in 85%…”
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UK Lung Cancer RCT Pilot Screening Trial: baseline findings from the screening arm provide evidence for the potential implementation of lung cancer screening by Field, J K, Duffy, S W, Baldwin, D R, Whynes, D K, Devaraj, A, Brain, K E, Eisen, T, Gosney, J, Green, B A, Holemans, J A, Kavanagh, T, Kerr, K M, Ledson, M, Lifford, K J, McRonald, F E, Nair, A, Page, R D, Parmar, M K B, Rassl, D M, Rintoul, R C, Screaton, N J, Wald, N J, Weller, D, Williamson, P R, Yadegarfar, G, Hansell, D M

“…Lung cancer screening using low-dose CT (LDCT) was shown to reduce lung cancer mortality by 20% in the National Lung Screening Trial. The pilot UK Lung Cancer…”
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Family history and risk of lung cancer: age-at-diagnosis in cases and first-degree relatives by CASSIDY, A, MYLES, J. P, DUFFY, S. W, LILOGLOU, T, FIELD, J. K

“…To investigate the little known risk of lung cancer at an early age when a first-degree relative has had such a diagnosis, 579 incident cases and 1157…”
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The Liverpool Lung Project research protocol by Field, J K, Smith, D L, Duffy, S, Cassidy, A

“…The Liverpool Lung Project (LLP) is being conducted within a defined geographic area of Merseyside, based on contiguous districts with a high incidence of lung…”
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