Search Results - "Field, John"
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Road map to improve the quality of lung cancer risk data
Published in Thorax (01-01-2024)Get more information
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Lung cancer LDCT screening and mortality reduction — evidence, pitfalls and future perspectives
Published in Nature reviews. Clinical oncology (01-03-2021)“…In the past decade, the introduction of molecularly targeted agents and immune-checkpoint inhibitors has led to improved survival outcomes for patients with…”
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Intelligibility and the Listener: The Role of Lexical Stress
Published in TESOL quarterly (01-09-2005)“…For some 30 years, intelligibility has been recognized as an appropriate goal for pronunciation instruction, yet remarkably little is known about the factors…”
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Was this career shaped by people or by chance?
Published in ICES journal of marine science (15-12-2021)“…Abstract This paper discusses the people and events that influenced my career and the lessons I learnt along the way. In this essay I attempt to pass these…”
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Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges
Published in Journal of thoracic oncology (01-03-2019)“…The present review is an update of the research and development efforts regarding the use of molecular biomarkers in the lung cancer screening setting. The two…”
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Mortality Reduction with Low-Dose CT Screening for Lung Cancer
Published in The New England journal of medicine (06-02-2020)“…Since the publication of the first mortality results from the National Lung Screening Trial (NLST), which showed a 20% reduction in lung-cancer mortality with…”
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European position statement on lung cancer screening
Published in The lancet oncology (01-12-2017)“…Lung cancer screening with low-dose CT can save lives. This European Union (EU) position statement presents the available evidence and the major issues that…”
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Habitat compression and ecosystem shifts as potential links between marine heatwave and record whale entanglements
Published in Nature communications (27-01-2020)“…Climate change and increased variability and intensity of climate events, in combination with recovering protected species populations and highly capitalized…”
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Heterogeneity of PD-L1 expression in non-small cell lung cancer: Implications for specimen sampling in predicting treatment response
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2019)“…•PD-L1 expression was assessed for heterogeneity in 107 NSCLC patients.•Intra-tumoural heterogeneity was observed in 78% of cases.•Inter-tumoural heterogeneity…”
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Impact of low-dose CT screening on smoking cessation among high-risk participants in the UK Lung Cancer Screening Trial
Published in Thorax (01-10-2017)“…Smoking cessation was examined among high-risk participants in the UK Lung Cancer Screening (UKLS) Pilot Trial of low-dose CT screening. High-risk individuals…”
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Prospects for population screening and diagnosis of lung cancer
Published in The Lancet (British edition) (24-08-2013)“…Summary Deaths from lung cancer exceed those from any other type of malignancy, with 1·5 million deaths in 2010. Prevention and smoking cessation are still the…”
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Robust paths to net greenhouse gas mitigation and negative emissions via advanced biofuels
Published in Proceedings of the National Academy of Sciences - PNAS (08-09-2020)“…Biofuel and bioenergy systems are integral to most climate stabilization scenarios for displacement of transport sector fossil fuel use and for producing…”
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Perspective: The screening imperative
Published in Nature (London) (11-09-2014)“…Lung cancer kills more people than any other malignancy. Let's not delay in implementing a screening programme, says John K. Field…”
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Treatment Characteristics and Real-World Progression-Free Survival in Patients With Unresectable Stage III NSCLC Who Received Durvalumab After Chemoradiotherapy: Findings From the PACIFIC-R Study
Published in Journal of thoracic oncology (01-02-2023)“…The phase 3 PACIFIC trial established consolidation therapy with durvalumab as standard of care for patients with unresectable, stage III NSCLC and no disease…”
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The American Association for Thoracic Surgery guidelines for lung cancer screening using low-dose computed tomography scans for lung cancer survivors and other high-risk groups
Published in The Journal of thoracic and cardiovascular surgery (01-07-2012)“…Objective Lung cancer is the leading cause of cancer death in North America. Low-dose computed tomography screening can reduce lung cancer–specific mortality…”
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SHOX2 DNA methylation is a biomarker for the diagnosis of lung cancer in plasma
Published in Journal of thoracic oncology (01-10-2011)“…Recently, analysis of DNA methylation of the SHOX2 locus was shown to reliably identify lung cancer in bronchial aspirates of patients with disease. As a…”
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Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis
Published in British journal of cancer (01-03-2020)“…Background Long non-coding RNAs compose an important level of epigenetic regulation in normal physiology and disease. Despite the plethora of publications of…”
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Spatiotemporal patterns of variability in the abundance and distribution of winter-spawned pelagic juvenile rockfish in the California Current
Published in PloS one (27-05-2021)“…Rockfish are an important component of West Coast fisheries and California Current food webs, and recruitment (cohort strength) for rockfish populations has…”
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Vertical distribution of mesopelagic fishes deepens during marine heatwave in the California Current
Published in ICES journal of marine science (23-09-2024)“…Abstract Marine heatwaves can impact the distribution and abundance of epipelagic organisms, but their effect on deep pelagic communities is unclear. Using…”
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SHOX2 DNA methylation is a biomarker for the diagnosis of lung cancer based on bronchial aspirates
Published in BMC cancer (03-11-2010)“…This study aimed to show that SHOX2 DNA methylation is a tumor marker in patients with suspected lung cancer by using bronchial fluid aspirated during…”
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