Search Results - "Fiebich, Bernd L"

Lipopolysaccharide-Induced Neuroinflammation as a Bridge to Understand Neurodegeneration by Batista, Carla Ribeiro Alvares, Gomes, Giovanni Freitas, Candelario-Jalil, Eduardo, Fiebich, Bernd L, de Oliveira, Antonio Carlos Pinheiro

“…A large body of experimental evidence suggests that neuroinflammation is a key pathological event triggering and perpetuating the neurodegenerative process…”
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Role of Microglia TLRs in Neurodegeneration by Fiebich, Bernd L, Batista, Carla Ribeiro Alvares, Saliba, Soraya Wilke, Yousif, Nizar M, de Oliveira, Antonio Carlos Pinheiro

“…Toll-like receptors (TLRs) are a group of receptors widely distributed in the organism. In the central nervous system, they are expressed in neurons,…”
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Antimalarial Drug Artemether Inhibits Neuroinflammation in BV2 Microglia Through Nrf2-Dependent Mechanisms by Okorji, Uchechukwu P., Velagapudi, Ravikanth, El-Bakoush, Abdelmeneim, Fiebich, Bernd L., Olajide, Olumayokun A.

“…Artemether, a lipid-soluble derivative of artemisinin has been reported to possess anti-inflammatory properties. In this study, we have investigated the…”
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Role of Nitric Oxide in Neurodegeneration: Function, Regulation, and Inhibition by Tewari, Devesh, Sah, Archana N, Bawari, Sweta, Nabavi, Seyed F, Dehpour, Ahmad R, Shirooie, Samira, Braidy, Nady, Fiebich, Bernd L, Vacca, Rosa A, Nabavi, Seyed M

“…Reactive nitrogen species (RNS) and reactive oxygen species (ROS), collectively known as reactive oxygen and nitrogen species (RONS), are the products of…”
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Alleviation of Microglial Activation Induced by p38 MAPK/MK2/PGE2 Axis by Capsaicin: Potential Involvement of other than TRPV1 Mechanism/s by Bhatia, Harsharan S., Roelofs, Nora, Muñoz, Eduardo, Fiebich, Bernd L.

“…Exaggerated inflammatory responses in microglia represent one of the major risk factors for various central nervous system’s (CNS) associated pathologies…”
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Anti-neuroinflammatory effects of Ginkgo biloba extract EGb761 in LPS-activated primary microglial cells by Gargouri, Brahim, Carstensen, Johanna, Bhatia, Harsharan S., Huell, Michael, Dietz, Gunnar P.H., Fiebich, Bernd L.

“…Neuroinflammation is a key factor of Alzheimer's disease (AD) and other neurodegenerative conditions. Microglia are the resident mononuclear immune cells of…”
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Turmeric Extract ( Curcuma longa ) Mediates Anti-Oxidative Effects by Reduction of Nitric Oxide, iNOS Protein-, and mRNA-Synthesis in BV2 Microglial Cells by Streyczek, Jana, Apweiler, Matthias, Sun, Lu, Fiebich, Bernd L

“…Plant-derived products have been used since the beginnings of human history to treat various pathological conditions. Practical experience as well as a growing…”
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Electrified microglia: Impact of direct current stimulation on diverse properties of the most versatile brain cell by Gellner, Anne-Kathrin, Reis, Janine, Fiebich, Bernd L., Fritsch, Brita

“…Transcranial direct current stimulation [(t)DCS], modulates cortical excitability and promotes neuroplasticity. Microglia has been identified to respond to…”
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Anti-neuroinflammatory effects of GPR55 antagonists in LPS-activated primary microglial cells by Saliba, Soraya Wilke, Jauch, Hannah, Gargouri, Brahim, Keil, Albrecht, Hurrle, Thomas, Volz, Nicole, Mohr, Florian, van der Stelt, Mario, Bräse, Stefan, Fiebich, Bernd L

“…Neuroinflammation plays a vital role in Alzheimer's disease and other neurodegenerative conditions. Microglia are the resident mononuclear immune cells of the…”
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The two-hit hypothesis for neuroinflammation: role of exogenous ATP in modulating inflammation in the brain by Fiebich, Bernd L, Akter, Shamima, Akundi, Ravi Shankar

“…Brain inflammation is a common occurrence following responses to varied insults such as bacterial infections, stroke, traumatic brain injury and…”
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Induction of Autophagy and Activation of SIRT‐1 Deacetylation Mechanisms Mediate Neuroprotection by the Pomegranate Metabolite Urolithin A in BV2 Microglia and Differentiated 3D Human Neural Progenitor Cells by Velagapudi, Ravikanth, Lepiarz, Izabela, El‐Bakoush, Abdelmeneim, Katola, Folashade O, Bhatia, Harsharan, Fiebich, Bernd L, Olajide, Olumayokun A

“…Scope Urolithin A is an anti‐inflammatory and neuroprotective gut‐derived metabolite from ellagitannins and ellagic acid in pomegranate, berries, and nuts. The…”
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microRNA‐26a modulates inflammatory response induced by toll‐like receptor 4 stimulation in microglia by Kumar, Asit, Bhatia, Harsharan Singh, Oliveira, Antonio Carlos Pinheiro, Fiebich, Bernd L.

“…MiRNAs, a family of small non‐coding RNAs, have emerged as novel post‐transcriptional regulators of numerous cellular responses. Although the involvement of…”
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Traditionally used Thai medicinal plants: In vitro anti-inflammatory, anticancer and antioxidant activities by Siriwatanametanon, Nisarat, Fiebich, Bernd L., Efferth, Thomas, Prieto, Jose M., Heinrich, Michael

“…In vitro anti-inflammatory, cytotoxicity, and antioxidant activities of nine anti-inflammatory remedies used traditionally in Thailand – Basella alba, Basella…”
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Punicalagin inhibits neuroinflammation in LPS‐activated rat primary microglia by Olajide, Olumayokun A, Kumar, Asit, Velagapudi, Ravikanth, Okorji, Uchechukwu P, Fiebich, Bernd L

“…SCOPE: In this study, the effects of punicalagin on neuroinflammation in LPS‐activated microglia were investigated. METHODS AND RESULTS: The ability of…”
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Licochalcone A Inhibits Prostaglandin E2 by Targeting the MAPK Pathway in LPS Activated Primary Microglia by Bhatia, Harsharan Singh, Apweiler, Matthias, Sun, Lu, Baron, Julian, Tirkey, Ashwini, Fiebich, Bernd L.

“…Neuroinflammation and oxidative stress are conditions leading to neurological and neuropsychiatric disorders. Natural compounds exerting anti-inflammatory and…”
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Inflammatory and cytotoxic effects of bifenthrin in primary microglia and organotypic hippocampal slice cultures by Gargouri, Brahim, Yousif, Nizar M, Bouchard, Michèle, Fetoui, Hamadi, Fiebich, Bernd L

“…Pyrethroids, such as bifenthrin (BF), are among the most widely used class of insecticides that pose serious risks to human and wildlife health. Pyrethroids…”
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Targeting Oxidative Stress: Novel Coumarin-Based Inverse Agonists of GPR55 by Apweiler, Matthias, Saliba, Soraya Wilke, Streyczek, Jana, Hurrle, Thomas, Gräßle, Simone, Bräse, Stefan, Fiebich, Bernd L

“…Oxidative stress is associated with different neurological and psychiatric diseases. Therefore, development of new pharmaceuticals targeting oxidative…”
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Anti-Neuroinflammatory Effects of Ginkgo biloba Extract EGb 761 in LPS-Activated BV2 Microglial Cells by Sun, Lu, Apweiler, Matthias, Tirkey, Ashwini, Klett, Dominik, Normann, Claus, Dietz, Gunnar P H, Lehner, Martin D, Fiebich, Bernd L

“…Inflammatory processes in the brain can exert important neuroprotective functions. However, in neurological and psychiatric disorders, it is often detrimental…”
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Anti-Neuroinflammatory Effects of a Macrocyclic Peptide-Peptoid Hybrid in Lipopolysaccharide-Stimulated BV2 Microglial Cells by Sun, Lu, Wilke Saliba, Soraya, Apweiler, Matthias, Akmermer, Kamil, Herlan, Claudine, Grathwol, Christoph, de Oliveira, Antônio Carlos Pinheiro, Normann, Claus, Jung, Nicole, Bräse, Stefan, Fiebich, Bernd L

“…Inflammation processes of the central nervous system (CNS) play a vital role in the pathogenesis of several neurological and psychiatric disorders like…”
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Increased IL-8 concentrations in the cerebrospinal fluid of patients with unipolar depression by Kuzior, Hanna, Fiebich, Bernd L., Yousif, Nizar M., Saliba, Soraya W., Ziegler, Christiane, Nickel, Kathrin, Maier, Simon J., Süß, Patrick, Runge, Kimon, Matysik, Miriam, Dersch, Rick, Berger, Benjamin, Robinson, Tilman, Venhoff, Nils, Kessler, Franziska, Blank, Thomas, Domschke, Katharina, Tebartz van Elst, Ludger, Endres, Dominique

“…Unipolar depression is a common and debilitating disorder. Immunological explanatory approaches have become increasingly important in recent years and can be…”
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