Spontaneous regression of an orbital Langerhans cell histiocytosis after biopsy: A case report. Spontaneous regression of an orbital Langerhans cell histiocytosis

Spontaneous regression of an orbital Langerhans cell histiocytosis after biopsy: A case report. Spontaneous regression of an orbital Langerhans cell histiocytosis

Langerhans histiocytosis or Langerhans cell histiocytosis (LCH) is a rare benign pathology representing less than 1% of orbital tumors. It can cause either localized or generalized lesions, leading to the destruction of hard and soft tissues. Eosinophilic granuloma is the most benign form and the pr...

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Bibliographic Details
Published in:Rare tumors Vol. 14
Main Authors: Yahiaoui, Safia, Ghorbel, Asma, Ben Zid, Khadija, Zarraa, Semia, Kchaou, Lina, FidaNoubigh, Kaabia, Wael, Bouguerra, Fadoua, Mousli, Alia, Abidi, Rim, Yousfi, Amani, Nadia, Boujelbene, Nasr, Chiraz
Format: Journal Article
Language:English
Published: London, England SAGE Publications 01-10-2022
Sage Publications Ltd
SAGE Publishing
Subjects:
Biopsy
Cancer
Case Report
Case reports
Eye diseases
Granuloma
Histiocytosis
Langerhans cell histiocytosis
Lesions
Leukocytes (eosinophilic)
Radiation therapy
Soft tissues
Tumors
biopsy
spontaneous regression
orbital tumors
Langerhans cell histiocytosis
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Summary:Langerhans histiocytosis or Langerhans cell histiocytosis (LCH) is a rare benign pathology representing less than 1% of orbital tumors. It can cause either localized or generalized lesions, leading to the destruction of hard and soft tissues. Eosinophilic granuloma is the most benign form and the predominant clinical presentation of LCH. We report a case of eosinophilic granuloma with orbital involvement in an 18-year-old male patient. Orbital radiotherapy was initially planned, but finally it was not performed due to a spontaneous regression of the lesion after the incisional biopsy. The presented case supports an expectant attitude given the possibility of a spontaneous regression after the biopsy, especially in small lesions. However, long-term follow-up is essential given the risk of recurrence.
ISSN:2036-3613
2036-3605
2036-3613
DOI:10.1177/20363613221135987