Search Results - "Ficiarà, Eleonora"
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Iron Deposition in Brain: Does Aging Matter?
Published in International journal of molecular sciences (01-09-2022)“…The alteration of iron homeostasis related to the aging process is responsible for increased iron levels, potentially leading to oxidative cellular damage…”
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Magnetic Iron Oxide Nanoparticles: Synthesis, Characterization and Functionalization for Biomedical Applications in the Central Nervous System
Published in Materials (02-02-2019)“…Magnetic Nanoparticles (MNPs) are of great interest in biomedicine, due to their wide range of applications. During recent years, one of the most challenging…”
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A mathematical model on Aβ blood–brain transport: Simulations of plaques’ formation in Alzheimer’s disease
Published in Medical hypotheses (01-12-2023)Get full text
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Alteration of Iron Concentration in Alzheimer's Disease as a Possible Diagnostic Biomarker Unveiling Ferroptosis
Published in International journal of molecular sciences (25-04-2021)“…Proper functioning of all organs, including the brain, requires iron. It is present in different forms in biological fluids, and alterations in its…”
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Iron Overload in Brain: Transport Mismatches, Microbleeding Events, and How Nanochelating Therapies May Counteract Their Effects
Published in International journal of molecular sciences (01-02-2024)“…Iron overload in many brain regions is a common feature of aging and most neurodegenerative diseases. In this review, the causes, mechanisms, mathematical…”
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Exploitation of the Antibacterial Properties of Photoactivated Curcumin as 'Green' Tool for Food Preservation
Published in International journal of molecular sciences (26-02-2022)“…In the search for non-chemical and green methods to counteract the bacterial contamination of foods, the use of natural substances with antimicrobial…”
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Beyond Oncological Hyperthermia: Physically Drivable Magnetic Nanobubbles as Novel Multipurpose Theranostic Carriers in the Central Nervous System
Published in Molecules (Basel, Switzerland) (30-04-2020)“…Magnetic Oxygen-Loaded Nanobubbles (MOLNBs), manufactured by adding Superparamagnetic Iron Oxide Nanoparticles (SPIONs) on the surface of polymeric…”
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Iron Transport across Brain Barriers: Model and Numerical Parameter Estimation
Published in Mathematics (Basel) (01-11-2022)“…Iron is an essential element for brain metabolism. However, its imbalance and accumulation are implicated in the processes featuring neurodegenerative…”
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Step-by-Step Design of New Theranostic Nanoformulations: Multifunctional Nanovectors for Radio-Chemo-Hyperthermic Therapy under Physical Targeting
Published in Molecules (Basel, Switzerland) (29-07-2021)“…While investigating the possible synergistic effect of the conventional anticancer therapies, which, taken individually, are often ineffective against critical…”
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Machine Learning Profiling of Alzheimer's Disease Patients Based on Current Cerebrospinal Fluid Markers and Iron Content in Biofluids
Published in Frontiers in aging neuroscience (22-02-2021)“…Alzheimer's disease (AD) is the most common form of dementia, characterized by a complex etiology that makes therapeutic strategies still not effective. A true…”
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A Phase I Dose Escalation Study of Oxaliplatin, Cisplatin and Doxorubicin Applied as PIPAC in Patients with Peritoneal Carcinomatosis
Published in Cancers (03-03-2021)“…Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) is an innovative laparoscopic intraperitoneal chemotherapy approach with the advantage of a deeper…”
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Predicting Progression from Mild Cognitive Impairment to Alzheimer's Disease using MRI-based Cortical Features and a Two-State Markov Model
Published in 2021 IEEE 18th International Symposium on Biomedical Imaging (ISBI) (01-04-2021)“…Magnetic resonance imaging (MRI) has a potential for early diagnosis of individuals at risk for developing Alzheimer's disease (AD). Cognitive performance in…”
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Conference Proceeding Journal Article -
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Developing Iron Nanochelating Agents: Preliminary Investigation of Effectiveness and Safety for Central Nervous System Applications
Published in International journal of molecular sciences (01-01-2024)“…Excessive iron levels are believed to contribute to the development of neurodegenerative disorders by promoting oxidative stress and harmful protein…”
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Magnetic Iron-Chelating Nanobubbles for Boosting Therapies Effectiveness in the CNS
Published in 2024 IEEE 24th International Conference on Nanotechnology (NANO) (08-07-2024)“…Brain iron overload is a hallmark of many neurodegenerative diseases. Local chelating therapy poses many challenges due to the presence of very selective…”
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Conference Proceeding