Search Results - "Fibuch, Eugene E."
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Modulation of D2R-NR2B Interactions in Response to Cocaine
Published in Neuron (Cambridge, Mass.) (07-12-2006)“…Dopamine-glutamate interactions in the neostriatum determine psychostimulant action, but the underlying molecular mechanisms remain elusive. Here we found that…”
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2
Regulation of mitogen-activated protein kinases by glutamate receptors
Published in Journal of neurochemistry (01-01-2007)“…Glutamate receptors regulate gene expression in neurons by activating intracellular signaling cascades that phosphorylate transcription factors within the…”
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3
Roles of subunit phosphorylation in regulating glutamate receptor function
Published in European journal of pharmacology (05-04-2014)“…Protein phosphorylation is an important mechanism for regulating ionotropic glutamate receptors (iGluRs). Early studies have established that major iGluR…”
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4
Extended swimming exercise reduces inflammatory and peripheral neuropathic pain in rodents
Published in The journal of pain (01-12-2007)“…Physical exercise is often recommended to patients who have chronic pain. However, only a small number of studies report exercise-induced analgesia in the…”
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Phosphorylation and feedback regulation of metabotropic glutamate receptor 1 by calcium/calmodulin-dependent protein kinase II
Published in The Journal of neuroscience (20-02-2013)“…The metabotropic glutamate receptor 1 (mGluR1) is a Gα(q)-protein-coupled receptor and is distributed in broad regions of the mammalian brain. As a key element…”
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6
Amphetamine increases phosphorylation of MAPK/ERK at synaptic sites in the rat striatum and medial prefrontal cortex
Published in Brain research (04-02-2013)“…Abstract Mitogen-activated protein kinases (MAPKs) play a central role in cell signaling. Extracellular signal-regulated kinase (ERK) is a prototypic subclass…”
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Non-analgesic effects of opioids: opioids and the endocrine system
Published in Current pharmaceutical design (01-12-2012)“…Opioids are among the oldest known and most widely used analgesics. The application of opioids has expanded over the last few decades, especially in the…”
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Stability of surface NMDA receptors controls synaptic and behavioral adaptations to amphetamine
Published in Nature neuroscience (01-05-2009)“…This study shows that chronic amphetamine exposure in rats downregulates the NMDA receptor NR2B subunit on striatal neurons. This loss of NR2B has consequences…”
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Propofol inhibits phosphorylation of N-methyl-D-aspartate receptor NR1 subunits in neurons
Published in Anesthesiology (Philadelphia) (01-04-2006)“…Anesthetics may interact with ionotropic glutamate receptors to produce some of their biologic actions. Cellular studies reveal that the ionotropic glutamate…”
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Inhibition of glutamatergic activation of extracellular signal-regulated protein kinases in hippocampal neurons by the intravenous anesthetic propofol
Published in Anesthesiology (Philadelphia) (01-12-2006)“…Intravenous anesthetics cause amnesia, but the underlying molecular mechanisms are poorly understood. Recent studies reveal a significant role of extracellular…”
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11
Phosphorylation of group I metabotropic glutamate receptors (mGluR1/5) in vitro and in vivo
Published in Neuropharmacology (01-09-2008)“…Group I metabotropic glutamate receptors (mGluR1 and mGluR5 subtypes) are densely expressed in mammalian brain. They are actively involved in the regulation of…”
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In vivo regulation of Homer1a expression in the striatum by cocaine
Published in Molecular pharmacology (01-04-2007)“…The glutamate receptor adaptor protein Homer is concentrated in the postsynaptic density of excitatory synapses and is critical for normal operation of…”
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13
Regulation of group I metabotropic glutamate receptor expression in the rat striatum and prefrontal cortex in response to amphetamine in vivo
Published in Brain research (22-04-2010)“…Abstract G protein-coupled metabotropic glutamate receptors (mGluRs) are expressed in widespread regions of the mammalian brain and are involved in the…”
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14
Role of Protein Phosphatase 2A in mGluR5-regulated MEK/ERK Phosphorylation in Neurons
Published in The Journal of biological chemistry (01-04-2005)“…The regulation of protein phosphorylation requires coordinated interaction between protein kinases and protein phosphatases (PPs). Recent evidence has shown…”
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15
Post-translational modification biology of glutamate receptors and drug addiction
Published in Frontiers in neuroanatomy (2011)“…Post-translational covalent modifications of glutamate receptors remain a hot topic. Early studies have established that this family of receptors, including…”
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Phosphorylation of glutamate receptors: A potential mechanism for the regulation of receptor function and psychostimulant action
Published in Journal of neuroscience research (01-12-2006)“…Ionotropic glutamate receptors, N‐methyl‐d‐aspartate receptors (NMDARs) and α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionic acid receptors (AMPARs), are…”
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Modulation of ionotropic glutamate receptors and Acid-sensing ion channels by nitric oxide
Published in Frontiers in physiology (01-01-2012)“…Ionotropic glutamate receptors (iGluR) are ligand-gated ion channels and are densely expressed in broad areas of mammalian brains. Like iGluRs, acid-sensing…”
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Alterations in subcellular expression of acid-sensing ion channels in the rat forebrain following chronic amphetamine administration
Published in Neuroscience research (01-09-2010)“…Acid-sensing ion channels (ASICs) are densely expressed in broad areas of mammalian brains and actively modulate synaptic transmission and a variety of…”
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The endocrine effects of long-term oral opioid therapy: a case report and review of the literature
Published in Journal of opioid management (01-03-2011)“…The negative effects of long-term opioid administration on the body's endocrine system have been known for decades. These effects have been observed and…”
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Inhaled Anesthetics Promote Albumin Dimerization through Reciprocal Exchange of Subdomains
Published in Biochemistry Research International (01-01-2010)“…Inhaled anesthetics affect protein-protein interaction, but the mechanisms underlying these effects are still poorly understood. We examined the impact of…”
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