Search Results - "Fibbi, G."

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  1. 1

    Endothelial Progenitor Cells in Sprouting Angiogenesis: Proteases Pave the Way by Laurenzana, A, Fibbi, G, Margheri, F, Biagioni, A, Luciani, C, Del Rosso, M, Chillà, A

    Published in Current molecular medicine (01-09-2015)
    “…Sprouting angiogenesis consists of the expansion and remodelling of existing vessels, where the vascular sprouts connect each other to form new vascular loops…”
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    Type II CRISPR/Cas9 approach in the oncological therapy by Biagioni, A, Chillà, A, Andreucci, E, Laurenzana, A, Margheri, F, Peppicelli, S, Del Rosso, M, Fibbi, G

    “…CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a prokaryotic adaptable immune mechanism used by many bacteria and archaea to protect…”
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    u-PAR expression in cancer associated fibroblast: new acquisitions in multiple myeloma progression by Ciavarella, S, Laurenzana, A, De Summa, S, Pilato, B, Chillà, A, Lacalamita, R, Minoia, C, Margheri, F, Iacobazzi, A, Rana, A, Merchionne, F, Fibbi, G, Del Rosso, M, Guarini, A, Tommasi, S, Serratì, S

    Published in BMC cancer (24-03-2017)
    “…Multiple Myeloma (MM) is a B-cell malignancy in which clonal plasma cells progressively expand within the bone marrow (BM) as effect of complex interactions…”
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    Systemic sclerosis fibroblasts inhibit in vitro angiogenesis by MMP-12-dependent cleavage of the endothelial cell urokinase receptor by Serratì, S, Cinelli, M, Margheri, F, Guiducci, S, Del Rosso, A, Pucci, M, Fibbi, G, Bazzichi, L, Bombardieri, S, Matucci-Cerinic, M, Del Rosso, M

    Published in The Journal of pathology (01-10-2006)
    “…Failure of endothelial cells to develop new vessels in response to hypoxia is a distinctive feature of systemic sclerosis (SSc) in the avascular phase. We have…”
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    Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases by MARGHERI, F, D'ALESSIO, S, RUCCI, N, BOLOGNA, M, TETI, A, MONIA, B, FIBBI, G, DEL ROSSO, M, SERRATI, S, PUCCI, M, ANNUNZIATO, F, COSMI, L, LIOTTA, F, ANGELI, R, ANGELUCCI, A, GRAVINA, G. L

    Published in Gene therapy (01-04-2005)
    “…An important factor implicated in tumor cell predisposition for invasion and metastasis is the malignancy-related upregulation of urokinase plasminogen…”
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    Deflazacort modulates the fibrinolytic pattern and reduces uPA-dependent chemioinvasion and proliferation in rheumatoid arthritis synoviocytes by Del Rosso, A., Cinelli, M., Guiducci, S., Pignone, A., Fibbi, G., Margheri, F., Gabrielli, A., Giacomelli, R., Coppini, A., Del Rosso, M., Matucci Cerinic, M.

    Published in Rheumatology (Oxford, England) (01-10-2005)
    “…Objective. Extracellular fibrinolysis, controlled by the cell-associated fibrinolytic system (urokinase plasminogen activator, uPA; uPA receptor, uPAR;…”
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    Piascledine modulates the production of VEGF and TIMP-1 and reduces the invasiveness of rheumatoid arthritis synoviocytes by Cinelli, M., Guiducci, S., Del Rosso, A., Pignone, A., Del Rosso, M., Fibbi, G., Serratì, S., Gabrielli, A., Giacomelli, R., Piccardi, N., Matucci Cerinic, M.

    Published in Scandinavian journal of rheumatology (01-01-2006)
    “…Background: In rheumatoid arthritis (RA), hypertrophy of the synovial membrane generates a tumour-like pannus that invades the joint cavity and erodes…”
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  9. 9

    The urokinase-type plasminogen activator system and inflammatory joint diseases by DEL ROSSO, M, FIBBI, G, CERINIC, M. M

    Published in Clinical and experimental rheumatology (01-07-1999)
    “…Much evidence indicates that the urokinase plasminogen activator (u-PA), the urokinase receptor (u-PAR) and the serpin inhibitors are critical in cell invasion…”
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  10. 10

    Raloxifene reduces urokinase-type plasminogen activator-dependent proliferation of synoviocytes from patients with rheumatoid arthritis by Guiducci, S, Del Rosso, A, Cinelli, M, Perfetto, F, Livi, R, Rossi, A, Gabrielli, A, Giacomelli, R, Iori, N, Fibbi, G, Del Rosso, M, Cerinic, M Matucci

    Published in Arthritis research & therapy (01-01-2005)
    “…Extracellular fibrinolysis, controlled by the membrane-bound fibrinolytic system, is involved in cartilage damage and rheumatoid arthritis (RA) synovitis…”
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  11. 11

    Urokinase-urokinase receptor interaction: non-mitogenic signal transduction in human epidermal cells by Del Rosso, M, Anichini, E, Pedersen, N, Blasi, F, Fibbi, G, Pucci, M, Ruggiero, M

    “…We studied non-mitogenic signal transduction in a human cell line of epidermal origin which is induced to chemotaxis following stimulation with human…”
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  12. 12

    Transforming Growth Factor Beta-1 Stimulates Invasivity of Hepatic Stellate Cells by Engagement of the Cell-associated Fibrinolytic System by Fibbi, Gabriella, Pucci, Marco, D'alessio, Silvia, Grappone, Cecilia, Pellegrini, Giulia, Salzano, Renata, Casini, Alessandro, Milani, Stefano, Rosso, Mario Del

    “…The activation of hepatic stellate cells (HSC) during liver fibrogenesis has been shown to be mediated by paracrine and autocrine loops involving transforming…”
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  13. 13

    Interaction of urokinase with specific receptors stimulates mobilization of bovine adrenal capillary endothelial cells by Fibbi, G, Ziche, M, Morbidelli, L, Magnelli, L, Del Rosso, M

    Published in Experimental cell research (01-12-1988)
    “…On the basis of 125I-labeled plasminogen activator binding analysis we have found that bovine adrenal capillary endothelial cells have specific receptors for…”
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    Antisense targeting of the urokinase receptor blocks urokinase-dependent proliferation, chemoinvasion, and chemotaxis of human synovial cells and chondrocytes in vitro by Fibbi, G, Pucci, M, Serni, U, Cerinic, M M, Del Rosso, M

    “…Proliferation and invasion of synovial pannus in rheumatoid arthritis and cartilage remodeling in osteoarthritis are key events in development of disability of…”
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    Control of the chondrocyte fibrinolytic balance by the drug piroxicam: relevance to the osteoarthritic process by Fibbi, G, Serni, U, Matucci, A, Mannoni, A, Pucci, M, Anichini, E, Del Rosso, M

    Published in Journal of rheumatology (01-12-1994)
    “…Since the plasminogen activator [PA/plasminogen activator inhibitor (PAI) system is believed to be involved in a breakdown of articular cartilage in…”
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  17. 17

    Interaction of urokinase A chain with the receptor of human keratinocytes stimulates release of urokinase-like plasminogen activator by Fibbi, G, Magnelli, L, Pucci, M, Del Rosso, M

    Published in Experimental cell research (01-03-1990)
    “…On the basis of a fibrinolytic assay with 125I-fibrin, zymography, and immunoprobing with anti-human urokinase antibody, we have observed that the in vitro…”
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    Plasminogen activator and receptor in osteoarthritis by Serni, U, Fibbi, G, Anichini, E, Zamperini, A, Pucci, M, Mannoni, A, Matucci, A, Benucci, M, Del Rosso, A, Del Rosso, M

    Published in Journal of rheumatology. Supplement (01-02-1995)
    “…Evidence indicates that breakdown of articular cartilage resulting in the loss of normal joint function is the distinctive feature of osteoarthritis…”
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    Multiple pathways of cell invasion are regulated by multiple families of serine proteases by Del Rosso, Mario, Fibbi, Gabriella, Pucci, Marco, D'Alessio, Silvia, Del Rosso, Angela, Magnelli, Lucia, Chiarugi, Vincenzo

    Published in Clinical & experimental metastasis (01-01-2002)
    “…The complex process of tumor invasion requires the coordinated expression and activity of cell-substratum adhesive interactions and of cell-associated protease…”
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