Search Results - "Fiammenghi, Laura"
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Evaluation of in vivo labelled dendritic cell migration in cancer patients
Published in Journal of translational medicine (30-07-2004)“…BACKGROUND: Dendritic Cell (DC) vaccination is a very promising therapeutic strategy in cancer patients. The immunizing ability of DC is critically influenced…”
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Improved overall survival in dendritic cell vaccination-induced immunoreactive subgroup of advanced melanoma patients
Published in Journal of translational medicine (16-08-2006)“…We present our experience of therapeutic vaccination using dendritic cells (DC) pulsed with autologous tumor antigens in patients with advanced melanoma…”
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Unexpected High Response Rate to Traditional Therapy after Dendritic Cell-Based Vaccine in Advanced Melanoma: Update of Clinical Outcome and Subgroup Analysis
Published in Clinical & developmental immunology (01-01-2010)“…We reviewed the clinical results of a dendritic cell-based phase II clinical vaccine trial in stage IV melanoma and analyzed a patient subgroup treated with…”
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FRET microscopy autologous tumor lysate processing in mature dendritic cell vaccine therapy
Published in Journal of translational medicine (03-06-2010)“…Antigen processing by dendritic cells (DC) exposed to specific stimuli has been well characterized in biological studies. Nonetheless, the question of whether…”
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Erratum to “Unexpected High Response Rate to Traditional Therapy after Dendritic Cell-Based Vaccine in Advanced Melanoma: Update of Clinical Outcome and Subgroup Analysis”
Published in Clinical & developmental immunology (2011)“…The authors would like to add Dr. LindaValmorriat to the authors' list. Thus, the authors' list will be:Laura Ridolfi, Massimiliano Petrini, Laura Fiammenghi,…”
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Skewing effect of sulprostone on dendritic cell maturation compared with dinoprostone
Published in Cytotherapy (Oxford, England) (01-06-2018)“…Abstract Background Dendritic cells (DCs) are the most efficient antigen-presenting cells and act at the center of the immune system owing to their ability to…”
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Low-dose temozolomide before dendritic-cell vaccination reduces (specifically) CD4+CD25++Foxp3+ regulatory T-cells in advanced melanoma patients
Published in Journal of translational medicine (31-05-2013)“…In cancer immunotherapy, dendritic cells (DCs) play a fundamental role in the dialog between innate and adaptive immune response, but several immunosuppressive…”
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Complementary vaccination protocol with dendritic cells pulsed with autologous tumour lysate in patients with resected stage III or IV melanoma: protocol for a phase II randomised trial (ACDC Adjuvant Trial)
Published in BMJ open (01-08-2018)“…IntroductionSurgery is one of the treatments of choice for patients with a single metastasis from melanoma but is rarely curative. Such patients could…”
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Dendritic cell vaccination for metastatic melanoma: a 14-year monoinstitutional experience
Published in Melanoma research (01-08-2017)“…Although immunomodulating antibodies are highly effective in metastatic melanoma, their toxicity, related to the activation of T lymphocytes, can be severe…”
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Vaccination with autologous dendritic cells loaded with autologous tumor lysate or homogenate combined with immunomodulating radiotherapy and/or preleukapheresis IFN-α in patients with metastatic melanoma: a randomised "proof-of-principle" phase II study
Published in Journal of translational medicine (22-07-2014)“…Vaccination with dendritic cells (DC) loaded with tumor antigens elicits tumor-specific immune responses capable of killing cancer cells without inducing…”
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Radiotherapy as an immunological booster in patients with metastatic melanoma or renal cell carcinoma treated with high-dose interleukin-2: Interim analysis data
Published in Journal of clinical oncology (20-05-2015)“…Abstract only…”
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Human embryo immune escape mechanisms rediscovered by the tumor
Published in Immunobiology (1979) (01-01-2009)“…Abstract Towards the end of the 1990s, the two opposing theories on immunosurveillance and immunostimulation were extensively studied by researchers in an…”
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Effect of vaccination with autologous tumor-loaded dendritic cells on intratumoral regulatory T cells in metastatic melanoma patients
Published in Journal of clinical oncology (20-05-2013)“…Abstract only 3040 Background: Vaccination with dendritic cells (DC) is still a valid experimental option for metastatic melanoma (MM). However, only a few…”
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Vaccination with autologous dendritic cells loaded with autologous tumor lysate or homogenate combined with immunomodulating radiotherapy and/or preleukapheresis IFN-[alpha] in patients with metastatic melanoma: a randomised "proof-of-principle" phase II study
Published in Journal of translational medicine (22-07-2014)“…Background Vaccination with dendritic cells (DC) loaded with tumor antigens elicits tumor-specific immune responses capable of killing cancer cells without…”
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A Dendritic Cell (DC) microRNA signature predicts clinical outcome in Melanoma Patients treated with DC vaccine
Published in Frontiers in immunology (2013)“…Abstract only…”
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Dendritic cell-based vaccine in advanced melanoma: update of clinical outcome
Published in Melanoma research (01-12-2011)“…Dendritic cells (DCs) are unique specialized antigen-presenting cells capable of priming naive T cells and inducing antigen-specific cytotoxic T lymphocytes…”
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Review: Human embryo immune escape mechanisms rediscovered by the tumor
Published in Immunobiology (1979) (01-01-2009)“…Towards the end of the 1990s, the two opposing theories on immunosurveillance and immunostimulation were extensively studied by researchers in an attempt to…”
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Tumor endothelial marker 8 expression levels in dendritic cell-based cancer vaccines are related to clinical outcome
Published in Cancer Immunology, Immunotherapy (01-01-2010)“…Previous studies have shown that tumor endothelial markers (TEMs 1-9) are up modulated in immunosuppressive, pro-angiogenic dendritic cells (DCs) found in…”
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Low-dose temozolomide before dendritic-cell vaccination reduces (specifically) CD4 super(+)CD25 super(++)Fox p3 super(+) regulatory T-cells in advanced melanoma patients
Published in Journal of translational medicine (01-01-2013)“…Background: In cancer immunotherapy, dendritic cells (DCs) play a fundamental role in the dialog between innate and adaptive immune response, but several…”
Get full text
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