Search Results - "Fialho, Luz Sousa"

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    Balancing adaptability and standardisation: insights from 27 routinely implemented ICHOM standard sets by Benning, Leo, Das-Gupta, Zofia, Sousa Fialho, Luz, Wissig, Stephanie, Tapela, Neo, Gaunt, Suzanne

    Published in BMC health services research (28-11-2022)
    “…Healthcare systems around the world experience increasing pressure to control future growth of healthcare expenditures. Among other initiatives, quality and…”
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    Journal Article
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    L-Carnitine Stimulates In Vivo Carbohydrate Metabolism in the Type 1 Diabetic Heart as Demonstrated by Hyperpolarized MRI by Savic, Dragana, Ball, Vicky, Curtis, M Kate, Sousa Fialho, Maria da Luz, Timm, Kerstin N, Hauton, David, West, James, Griffin, Julian, Heather, Lisa C, Tyler, Damian J

    Published in Metabolites (23-03-2021)
    “…The diabetic heart is energetically and metabolically abnormal, with increased fatty acid oxidation and decreased glucose oxidation. One factor contributing to…”
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    Journal Article
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    Hypoxia-inducible factor 1 signalling, metabolism and its therapeutic potential in cardiovascular disease by Sousa Fialho, Maria da Luz, Abd Jamil, Amira H., Stannard, George A., Heather, Lisa C.

    “…Cardiovascular disease (CVD) accounts for the largest number of deaths worldwide, necessitating the development of novel treatments and prevention strategies…”
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    Journal Article
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    Activation of HIF1α Rescues the Hypoxic Response and Reverses Metabolic Dysfunction in the Diabetic Heart by Sousa Fialho, Maria da Luz, Purnama, Ujang, Dennis, Kaitlyn M J H, Montes Aparicio, Claudia N, Castro-Guarda, Marcos, Massourides, Emmanuelle, Tyler, Damian J, Carr, Carolyn A, Heather, Lisa C

    Published in Diabetes (New York, N.Y.) (01-11-2021)
    “…Type 2 diabetes (T2D) impairs hypoxia-inducible factor (HIF)1α activation, a master transcription factor that drives cellular adaptation to hypoxia. Reduced…”
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    Journal Article
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    The challenge of ensuring affordability, sustainability, consistency, and adaptability in the common metrics agenda by Krause, Karolin Rose, Chung, Sophie, Sousa Fialho, Maria da Luz, Szatmari, Peter, Wolpert, Miranda

    Published in The Lancet. Psychiatry (01-12-2021)
    “…Mental health research grapples with research waste and stunted field progression caused by inconsistent outcome measurement across studies and clinical…”
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    Journal Article
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    Pharmacological manipulation of hypoxic signalling as a therapeutic target to improve metabolism and function in the type 2 diabetic heart by Fialho, Maria da Luz Sousa

    Published 01-01-2018
    “…The work presented in this thesis investigates the metabolic and functional benefits of metabolic modulatory treatment strategies in a rodent model of type 2…”
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    Dissertation