Search Results - "Fiala, E."

Feasibility of whole genome and transcriptome profiling in pediatric and young adult cancers by Shukla, N., Levine, M. F., Gundem, G., Domenico, D., Spitzer, B., Bouvier, N., Arango-Ossa, J. E., Glodzik, D., Medina-Martínez, J. S., Bhanot, U., Gutiérrez-Abril, J., Zhou, Y., Fiala, E., Stockfisch, E., Li, S., Rodriguez-Sanchez, M. I., O’Donohue, T., Cobbs, C., Roehrl, M. H. A., Benhamida, J., Iglesias Cardenas, F., Ortiz, M., Kinnaman, M., Roberts, S., Ladanyi, M., Modak, S., Farouk-Sait, S., Slotkin, E., Karajannis, M. A., Dela Cruz, F., Glade Bender, J., Zehir, A., Viale, A., Walsh, M. F., Kung, A. L., Papaemmanuil, E.

“…The utility of cancer whole genome and transcriptome sequencing (cWGTS) in oncology is increasingly recognized. However, implementation of cWGTS is challenged…”
Get full text

Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors by EHRLICH, M, WOODS, C. B, LAIRD, P. W, YU, M. C, DUBEAU, L, YANG, F, CAMPAN, M, WEISENBERGER, D. J, LONG, T. I, YOUN, B, FIALA, E. S

“…How hypermethylation and hypomethylation of different parts of the genome in cancer are related to each other and to DNA methyltransferase (DNMT) gene…”
Get full text

The Religious Support Scale: Construction, Validation, and Cross‐Validation by Fiala, William E., Bjorck, Jeffrey P., Gorsuch, Richard

“…Cutrona and Russell's social support model was used to develop a religious support measure (C. E. Cutrona & D. W. Russell, 1987), including 3 distinct but…”
Get full text

Induction of UDP-glucuronosyltransferase 1 (UDP-GT1) gene complex by green tea in male F344 rats by Embola, C.W., Sohn, O.S., Fiala, E.S., Weisburger, J.H.

“…Tea is one of the most frequently consumed beverages in the world, second only to water. Epidemiological studies have associated the consumption of green tea…”
Get full text

Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol by OCK SOON SOHN, FIALA, Emerich S, REQUEIJO, Silvia P, WEISBURGER, John H, GONZALEZ, Frank J

“…Methylazoxymethanol (MAM) and its chemical and metabolic precursor, azoxymethane (AOM), both strong colon carcinogens in rodents, can be metabolically…”
Get full text

Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation by FIALA, E. S, STARETZ, M. E, PANDYA, G. A, EL-BAYOUMY, K, HAMILTON, S. R

Get full text

Prolonged culture of normal chorionic villus cells yields ICF syndrome-like chromatin decondensation and rearrangements by Tsien, F, Fiala, E S, Youn, B, Long, T I, Laird, P W, Weissbecker, K, Ehrlich, M

“…Untreated cultures from normal chorionic villus (CV) or amniotic fluid-derived (AF) samples displayed dramatic cell passage-dependent increases in aberrations…”
Get more information

Comparative effects of phenylenebis(methylene)selenocyanate isomers on xenobiotic metabolizing enzymes in organs of female CD rats by Sohn, Ock Soon, Fiala, Emerich S., Upadhyaya, Pramod, Chae, Young-Heum, El-Bayoumy, Karam

“…The cancer chemopreventive agent 1,4-phenylenebis-(methylene)selenocyanate (p-XSC) inhibits various chemically induced tumors in laboratory animals. We…”
Get full text

Effects of green and black tea on hepatic xenobiotic metabolizing systems in the male F344 rat by Sohn, O S, Surace, A, Fiala, E S, Richie, Jr, J P, Colosimo, S, Zang, E, Weisburger, J H

“…1. The induction of phase I and II enzymes in the liver of the male F344 rat drinking 2% (w/v) solutions of green or black tea for 6 weeks was investigated…”
Get more information

Mechanisms of Organoselenium Compounds in Chemoprevention: Effects on Transcription Factor-DNA Binding by Woo Youn, B., Fiala, Emerich S., Soon Sohn, Ock

“…Data obtained on the effects of selenium compounds on regulatory transcription factor-DNA binding by other laboratories are briefly reviewed, and some of our…”
Get full text

Inhibition of 2-nitropropane-induced rat liver DNA and RNA damage by benzyl selenocyanate by FIALA, E. S, OCK SOON SOHN, LI, H, EL-BAYOUMY, K, SODUM, R. S

“…We observed that pretreatment of male F344 rats with benzyl selenocyanate, a versatile organoselenium chemopreventive agent in several animal model systems,…”
Get full text

Analysis of Peroxynitrite Reactions with Guanine, Xanthine, and Adenine Nucleosides by High-Pressure Liquid Chromatography with Electrochemical Detection:  C8-Nitration and -Oxidation by Sodum, Rama S, Fiala, Emerich S

“…Peroxynitrite, the reaction product of nitric oxide and superoxide anion, and a powerful oxidant, was found to nitrate as well as oxidize adenine, guanine, and…”
Get full text

Metabolism of azoxymethane, methylazoxymethanol and N-nitrosodimethylamine by cytochrome P450IIE1 by Sohn, O S, Ishizaki, H, Yang, C S, Fiala, E S

“…The metabolism of azoxymethane (AOM), methylazoxymethanol (MAM) and N-nitrosodimethylamine (NDMA) by liver microsomes from acetone-induced rats as well as by a…”
Get more information

Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation by Fiala, E S, Staretz, M E, Pandya, G A, El-Bayoumy, K, Hamilton, S R

“…The organoselenium compounds benzyl selenocyanate (BSC) and 1,4-phenylenebis(methylene)selenocyanate (p-XSC), as well as sodium selenite, are effective…”
Get full text

Determination of 3-Nitrotyrosine by High-Pressure Liquid Chromatography with a Dual-Mode Electrochemical Detector by Sodum, Rama S., Akerkar, Shobha A., Fiala, Emerich S.

“…3-Nitrotyrosine, a product of tyrosine nitration, is useful as a marker for the generation of reactive nitrogen oxide species with short half-lives such as…”
Get full text

Synthesis and excretion profile of 1,4-[14C]phenylenebis(methylene)selenocyanate in the rat by EL-BAYOUMY, K, UPADHYAYA, P, SOHN, O.-S, ROSA, J. G, FIALA, E. S

“…1,4-Phenylenebis(methylene)selenocyanate (p-XSC) inhibits chemically induced tumors in several laboratory animal models. To understand its mode of action, we…”
Get full text

8-Aminoguanine: A base modification produced in rat liver nucleic acids by the hepatocarcinogen 2-nitropropane by Sodum, Rama S, Nie, Guo, Fiala, Emerich S

“…2-Nitropropane (2-NP), an important industrial chemical and a hepatocarcinogen in rats, had previously been found to produce several modifications of…”
Get full text

Chemoprevention of lung tumorigenesis induced by a mixture of benzo(a)pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate by Prokopczyk, B, Rosa, J G, Desai, D, Amin, S, Sohn, O S, Fiala, E S, El-Bayoumy, K

“…We evaluated the chemopreventive efficacy of the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate (p-XSC) against the development of tumors of…”
Get full text

Analysis of repetitive element DNA methylation by MethyLight by Weisenberger, Daniel J., Campan, Mihaela, Long, Tiffany I., Kim, Myungjin, Woods, Christian, Fiala, Emerich, Ehrlich, Melanie, Laird, Peter W.

“…Repetitive elements represent a large portion of the human genome and contain much of the CpG methylation found in normal human postnatal somatic tissues. Loss…”
Get full text

Secondary nitroalkanes: Induction of DNA repair in rat hepatocytes, activation by aryl sulfotransferase and hepatocarcinogenicity of 2-nitrobutane and 3-nitropentane in male F344 rats by Fiala, Emerich S., Sodum, Rama S., Hussain, Nalband S., Rivenson, Abraham, Dolan, Lisa

“…The secondary nitroalkanes, 2-nitropropane, 2-nitrobutane, 3-nitropentane, 2-nitroheptane, nitrocyclopentane and nitrocyclohexane, as well as the primary…”
Get full text