Search Results - "Fetni, Raouf"

SNP genotyping of a sclerosing rhabdomyosarcoma: reveals highly aneuploid profile and a specific MDM2 / HMGA2 amplification by Bouron-Dal Soglio, Dorothée, MD, Rougemont, Anne-Laure, MD, Absi, Riwa, MSc, Barrette, Stéphane, MD, Montpetit, Alexandre, PhD, Fetni, Raouf, PhD, Fournet, Jean-Christophe, MD, PhD

“…Summary Since the first description of sclerosing rhabdomyosarcoma in 2000, 19 pediatric cases have been reported in the literature. However, it is debated…”
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Cyclin-Dependent Kinases as a Therapeutic Target for Stroke by Osuga, H, Osuga, S, Wang, F, Fetni, R, Hogan, M J, Slack, R S, Hakim, A M, Ikeda, J E, Park, D S

“…Cyclin-dependent kinases (CDKs) are commonly known to regulate cell proliferation. However, previous reports suggest that in cultured postmitotic neurons,…”
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Activation of the phosphatidylinositol 3′-kinase/AKT pathway in neuroblastoma and its regulation by thioredoxin 1 by Sartelet, Hervé, MD, PhD, Rougemont, Anne-Laure, MD, Fabre, Monique, MD, Castaing, Marine, PhD, Duval, Michel, MD, PhD, Fetni, Raouf, PhD, Michiels, Stefan, PhD, Beaunoyer, Mona, MD, Vassal, Gilles, MD, PhD

“…Summary Neuroblastoma is a malignant pediatric tumor with poor survival. The phosphatidylinositol 3′-kinase/AKT pathway is a crucial regulator of cellular…”
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The Neuronal Apoptosis Inhibitory Protein Is a Direct Inhibitor of Caspases 3 and 7 by Maier, Johannes K. X, Lahoua, Zahia, Gendron, Nathalie H, Fetni, Raouf, Johnston, Anne, Davoodi, Jamshid, Rasper, Dita, Roy, Sophie, Slack, Ruth S, Nicholson, Donald W, MacKenzie, Alex E

“…The neuronal apoptosis inhibitory protein (NAIP) was identified as a candidate gene for the inherited neurodegenerative disorder spinal muscular atrophy. NAIP…”
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Overexpression of PRDM16 in the presence and absence of the RUNX1/PRDM16 fusion gene in myeloid leukemias by Hazourli, Sawcène, Chagnon, Pierre, Sauvageau, Martin, Fetni, Raouf, Busque, Lambert, Hébert, Josée

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A B-cell lymphoma–associated chromosomal translocation in a progressive transformation of germinal center by Bouron-Dal Soglio, Dorothée, MD, Truong, Françoise, MD, Fetni, Raouf, PhD, Hazourli, Sawcene, PhD, Champagne, Josette, MD, Oligny, Luc Laurier, MD, Fournet, Jean-Christophe, MD, PhD

“…Summary Progressive transformation of germinal center (PTGC) is a pattern of lymph node reactive hyperplasia. It can also be the predominant pattern in a…”
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CD133 expression is associated with poor outcome in neuroblastoma via chemoresistance mediated by the AKT pathway by Sartelet, Hervé, Imbriglio, Tina, Nyalendo, Carine, Haddad, Elie, Annabi, Borhane, Duval, Michel, Fetni, Raouf, Victor, Kokta, Alexendrov, Lubo, Sinnett, Daniel, Fabre, Monique, Vassal, Gilles

“…Sartelet H, Imbriglio T, Nyalendo C, Haddad E, Annabi B, Duval M, Fetni R, Victor K, Alexendrov L, Sinnett D, Fabre M & Vassal G 
(2012) Histopathology 60,…”
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Fragile site and interstitial telomere repeat sequences at the fusion point of a de novo (Y;13) translocation by BOUTOUIL, M, FETNI, R, QU, J, DALLAIRE, L, RICHER, C.-L, LEMIEUX, N

“…We describe a novel fragile site in a rearranged chromosome, associated with the presence of telomeric repeat sequences at the fusion point of a translocation…”
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Diagnostic utility of molecular and cytogenetic analysis in lipoblastoma: a study of two cases and review of the literature by Choi, Jungah, Bouron Dal Soglio, Dorothée, Fortier, Amanda, Fetni, Raouf, Mathonnet, Géraldine, Cournoyer, Sonia, Lallier, Michel, Isler, Marc, Beaulieu Bergeron, Mélanie, Patey, Natalie

“…Aims Lipoblastoma is a benign neoplasm of embryonic white fat tissue that results from the proliferation of primitive adipocytes, in which histological…”
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Genotype analysis of tumor-initiating cells expressing CD133 in neuroblastoma by Cournoyer, Sonia, Nyalendo, Carine, Addioui, Anissa, Belounis, Assila, Beaunoyer, Mona, Aumont, Anne, Teira, Pierre, Duval, Michel, Fernandes, Karl, Fetni, Raouf, Haddad, Elie, Sartelet, Hervé

“…Neuroblastoma (NB) is the most common and lethal extracranial solid tumor of childhood. Despite aggressive therapy, more than half of the children with…”
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SNP arrays: comparing diagnostic yields for four platforms in children with developmental delay by D'Amours, Guylaine, Langlois, Mathieu, Mathonnet, Géraldine, Fetni, Raouf, Nizard, Sonia, Srour, Myriam, Tihy, Frédérique, Phillips, Michael S, Michaud, Jacques L, Lemyre, Emmanuelle

“…Molecular karyotyping is now the first-tier genetic test for patients affected with unexplained intellectual disability (ID) and/or multiple congenital…”
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Allelic methylation bias of the RARB2 tumor suppressor gene promoter in cancer by Pappas, Jane J., Toulouse, André, Hébert, Josée, Fetni, Raouf, Bradley, W. E. C.

“…Retinoic acid receptor B2 (RARB2) is frequently inactivated in cancer. Methylation in the 5′‐untranslated region and first exon is known to play a role;…”
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Overexpression of MEL1 as a Novel Fusion Partner of AML1 in the Blastic Phase of Chronic Myeloid Leukemia with the Recurrent Cryptic Translocation t(1;21)(p36.3;q22) by Hazourli, Sawcene, Chagnon, Pierre, Fetni, Raouf, Busque, Lambert, Hebert, Josee

“…Located at 1p36.3, MEL1 is a member of the MDS1/EVI1 gene family and encodes a zinc finger protein with a N-terminal PR-domain. It has been proposed that the…”
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The Ubiquitin Specific Peptidase 42 Gene (USP42) Is Recurrently Involved as a Fusion Gene with RUNX1 in Acute Myeloid Leukemia with the t(7;21)(p22;q22) Cryptic Translocation by Giguere, Amelie, Hazourli, Sawcene, Meftah, Douja, Fetni, Raouf, Chagnon, Pierre, Hebert, Josee

“…The RUNX1 gene encodes the DNA-binding subunit of the heterodimeric transcription factor core binding factor (CBF) and is involved in the regulation of several…”
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Incidence of Genomic Aberrations and Associated Efficacy from a Phase III Study Comparing Alemtuzumab (CAMPATH®, MABCAMPATH®) vs Chlorambucil as First Line Therapy for B-Cell Chronic Lymphocytic Leukemia (BCLL) by Robak, Tadeusz, Dmoszynska, Anna, Fetni, Raouf, Wang, Ying, Belkacz, Malika, Sirard, Cynthia, Goldberg, Mark, Skotnicki, Aleksander, Mayer, Jiri, Hillmen, Peter

“…CAM307 is a randomized Phase III trial comparing the efficacy and safety of alemtuzumab (CAM) with chlorambucil (CHLO). The trial enrolled 297 previously…”
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Chondroid Cystic Malformation of the Lung With Trisomy 8 Mosaicism : A New Cystic Lung Malformation by BOURON-DAL SOGLIO, Dorothée, ROUGEMONT, Anne-Laure, DE BUYS ROESSINGH, Anthony S, FETNI, Raouf, RYPENS, Francoise, BOUCHARD, Sarah, MONTPETIT, Alexandre, FOURNET, Jean-Christophe

“…Neonatal cystic disorders of the lungs are a heterogeneous malformative group including giant lobar hyperinflation, congenital pulmonary airway malformations,…”
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A t(17;22)(q21;q12) with partial ETV4 deletion in a soft tissue Ewing sarcoma by Rougemont, Anne-Laure, Bouron-Dal Soglio, Dorothée, Patey-Mariaud de Serre, Natacha, Fetni, Raouf, Fan, Li, Barrette, Stéphane, Fournet, Jean-Christophe

“…Cytogenetic analysis of a lumbar soft tissue Ewing sarcoma (ES) in a 7-month-old female child showed a t(17;22)(q21;q12), a rare translocation leading to an…”
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Isolated central nervous system relapse in patients with chronic myeloid leukemia on imatinib mesylate by Johnson, Nathalie A, Fetni, Raouf, Caplan, Stephen N

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Prenatal cytogenetic assessment and inv(2)(p11.2q13) by Hysert, Meaghan, Bruyère, Hélène, Côté, Gilbert B., Dawson, Angelika J., Dolling, Jo-Anna, Fetni, Raouf, Hrynchak, Monica, Lavoie, Josée, McGowan-Jordan, Jean, Tihy, Frédérique, Duncan, Alessandra M. V.

“…Objectives To present a series of prenatally detected cases of recurrent pericentric inversions with euchromatic breakpoints and to review the literature to…”
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Frequency and phenotypic consequences of the 3199del6 CFTR mutation in French Canadians by Ruchon, Andrea Frota, Ryan, Shannon R., Fetni, Raouf, Rozen, Rima, Scott, Patrick

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