Search Results - "Fessler, Adam"

A novel SHAPE reagent enables the analysis of RNA structure in living cells with unprecedented accuracy by Marinus, Tycho, Fessler, Adam B, Ogle, Craig A, Incarnato, Danny

“…Abstract Due to the mounting evidence that RNA structure plays a critical role in regulating almost any physiological as well as pathological process, being…”
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Directly Quantifiable Biotinylation Using a Water-Soluble Isatoic Anhydride Platform by Fessler, Adam B, Fowler, Anthony J, Ogle, Craig A

“…Isatoic anhydride (IA) has been shown to be a useful platform for quantifiable bioconjugation. The elaboration of a water-soluble isatoic anhydride-based…”
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Innately Water-Soluble Isatoic Anhydrides with Modulated Reactivities for RNA SHAPE Analysis by Fessler, Adam B, Dey, Abhishek, Finis, Dominic S, Fowler, Anthony J, Chakrabarti, Kausik, Ogle, Craig A

“…1-Methyl-7-nitroisatoic anhydride (1M7) and 2-methylnicotinic acid imidazolide (NAI) are two of the most commonly applied RNA-SHAPE electrophiles; 1M7 due to…”
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Treatment of pancreatic ductal adenocarcinoma with tumor antigen specific-targeted delivery of paclitaxel loaded PLGA nanoparticles by Wu, Shu-Ta, Fowler, Anthony J, Garmon, Corey B, Fessler, Adam B, Ogle, Joshua D, Grover, Kajal R, Allen, Bailey C, Williams, Chandra D, Zhou, Ru, Yazdanifar, Mahboubeh, Ogle, Craig A, Mukherjee, Pinku

“…Pancreatic ductal adenocarcinoma (PDA) remains the most aggressive cancers with a 5-year survival below 10%. Systemic delivery of chemotherapy drugs has severe…”
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Water-Soluble Isatoic Anhydrides: A Platform for RNA-SHAPE Analysis and Protein Bioconjugation by Fessler, Adam B, Dey, Abhishek, Garmon, Corey B, Finis, Dominic S, Saleh, Nemah-Allah, Fowler, Anthony J, Jones, Daniel S, Chakrabarti, Kausik, Ogle, Craig A

“…N-(3-Iodopropyl)­isatoic anhydride (IPIA) has been demonstrated to serve as an efficient substrate for the development of an extended bioconjugation platform…”
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Design and Modulation of Novel Chemical Probes for RNA SHAPE Analysis: Water Soluble Isatoic Anhydrides and Nicotinic Acid Imidazolides by Fessler, Adam Bradley

“…The growing interest in RNA biology, along with an expansion in computational capabilities, throughput, and sensitivity has provided researchers new tools to…”
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Chemical Tools For Biology by Fessler, Adam Bradley

“…The ability to adapt compounds for specific applications in biological systems is crucial for the development of new pharmaceuticals and biotechnologies. The…”
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To PEGylate or not to PEGylate: Immunological properties of nanomedicine’s most popular component, polyethylene glycol and its alternatives by Shi, Da, Beasock, Damian, Fessler, Adam, Szebeni, Janos, Ljubimova, Julia Y., Afonin, Kirill A., Dobrovolskaia, Marina A.

“…[Display omitted] Polyethylene glycol or PEG has a long history of use in medicine. Many conventional formulations utilize PEG as either an active ingredient…”
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Green synthesis of cellulose graft copolymers for anion exchange water purification by Schmal, Steve C., Dosi, Raghav, Fessler, Adam, Kwiatkowski, Carly, Sahu, Abhispa, Poler, Jordan C.

“…A cellulose graft copolymer (cellulose nanoresin) was synthesized by the all-aqueous functionalization of cellouronic acid with poly (vinyl benzyl trimethyl…”
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To PEGylate or not to PEGylate: immunological properties of nanomedicine’s most popular component, poly(ethylene) glycol and its alternatives by Shi, Da, Beasock, Damian, Fessler, Adam, Szebeni, Janos, Ljubimova, Julia Y., Afonin, Kirill A., Dobrovolskaia, Marina A.

“…Poly(ethylene glycol) or PEG has a long history of use in medicine. Many conventional formulations utilize PEG as either an active ingredient or an excipient…”
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Anhydrous Nucleic Acid Nanoparticles for Storage and Handling at Broad Range of Temperatures by Tran, Allison N., Chandler, Morgan, Halman, Justin, Beasock, Damian, Fessler, Adam, McKeough, Riley Q., Lam, Phuong Anh, Furr, Daniel P., Wang, Jian, Cedrone, Edward, Dobrovolskaia, Marina A., Dokholyan, Nikolay V., Trammell, Susan R., Afonin, Kirill A.

“…Recent advances in nanotechnology now allow for the methodical implementation of therapeutic nucleic acids (TNAs) into modular nucleic acid nanoparticles…”
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