Search Results - "Fessenden, Tim"

Type I interferon activates MHC class I-dressed CD11b+ conventional dendritic cells to promote protective anti-tumor CD8+ T cell immunity by Duong, Ellen, Fessenden, Tim B., Lutz, Emi, Dinter, Teresa, Yim, Leon, Blatt, Sarah, Bhutkar, Arjun, Wittrup, Karl Dane, Spranger, Stefani

“…Tumor-infiltrating dendritic cells (DCs) assume varied functional states that impact anti-tumor immunity. To delineate the DC states associated with productive…”
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Tissue Site and the Cancer Immunity Cycle by Horton, Brendan L, Fessenden, Tim B, Spranger, Stefani

“…Checkpoint blockade immunotherapy (CBT) has revolutionized cancer treatment; however, the cellular and molecular factors that govern responsiveness to…”
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Acquired resistance to the second-generation androgen receptor antagonist enzalutamide in castration-resistant prostate cancer by Kregel, Steven, Chen, James L, Tom, Westin, Krishnan, Venkatesh, Kach, Jacob, Brechka, Hannah, Fessenden, Tim B, Isikbay, Masis, Paner, Gladell P, Szmulewitz, Russell Z, Vander Griend, Donald J

“…Enzalutamide (MDV3100) is a second generation Androgen Receptor (AR) antagonist with proven efficacy in the treatment of castration resistant prostate cancer…”
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Dia1-dependent adhesions are required by epithelial tissues to initiate invasion by Fessenden, Tim B, Beckham, Yvonne, Perez-Neut, Mathew, Ramirez-San Juan, Guillermina, Chourasia, Aparajita H, Macleod, Kay F, Oakes, Patrick W, Gardel, Margaret L

“…Developing tissues change shape and tumors initiate spreading through collective cell motility. Conserved mechanisms by which tissues initiate motility into…”
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Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes by Fordyce, Colleen A, Patten, Kelley T, Fessenden, Tim B, DeFilippis, RosaAnna, Hwang, E Shelley, Zhao, Jianxin, Tlsty, Thea D

“…Tumors are characterized by alterations in the epithelial and stromal compartments, which both contribute to tumor promotion. However, where, when, and how the…”
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Dendritic cell-mediated cross presentation of tumor-derived peptides is biased against plasma membrane proteins by Fessenden, Tim B, Stopfer, Lauren E, Chatterjee, Fiona, Zulueta, Julian, Mesfin, Josh, Cordero Dumit, Therese, Reijers, Irene, Hoefsmit, Esmee P, Blank, Christian, White, Forest, Spranger, Stefani

“…BackgroundFor effective tumor elimination, cytotoxic CD8+ T cells must recognize tumor-derived antigens presented on class I major histocompatibility complex…”
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You are the most valuable reagent in the lab: mental health before and during the pandemic by Fessenden, Tim

“…No one maps out their tenure as a postdoc anticipating a life-altering tragedy. But mental health crises of all kinds affect academic trainees and staff at…”
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Deciphering the immunopeptidome in vivo reveals new tumour antigens by Jaeger, Alex M., Stopfer, Lauren E., Ahn, Ryuhjin, Sanders, Emma A., Sandel, Demi A., Freed-Pastor, William A., Rideout, William M., Naranjo, Santiago, Fessenden, Tim, Nguyen, Kim B., Winter, Peter S., Kohn, Ryan E., Westcott, Peter M. K., Schenkel, Jason M., Shanahan, Sean-Luc, Shalek, Alex K., Spranger, Stefani, White, Forest M., Jacks, Tyler

“…Immunosurveillance of cancer requires the presentation of peptide antigens on major histocompatibility complex class I (MHC-I) molecules 1 – 5 . Current…”
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Deciphering the immunopeptidome in vivo reveals novel tumor antigens by Jaeger, Alex M., Stopfer, Lauren E., Ahn, Ryuhjin, Sanders, Emma A., Sandel, Demi A., Freed-Pastor, William A., Rideout, William M., Naranjo, Santiago, Fessenden, Tim, Nguyen, Kim B., Winter, Peter S., Kohn, Ryan E., Westcott, Peter M. K., Schenkel, Jason, Shanahan, Sean-Luc, Shalek, Alex K., Spranger, Stefani, White, Forest M., Jacks, Tyler

“…Immunosurveillance of cancer requires the presentation of peptide antigens on major histocompatibility complex class I (MHC-I) 1 , 2 , 3 , 4 , 5 . Current…”
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Abstract A03: Formins stabilize cell-ECM adhesions during invasion onset by Fessenden, Tim, Beckham, Yvonne, Perez-Neut, Mathew, Juan, Guillermina Ramirez-San, Gardel, Margaret L.

“…Abstract The onset of local invasion typically defines the transition from benign to malignant tumors. This pathological definition has clear implications for…”
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DNA damage drives an activin a-dependent induction of cyclooxygenase-2 in premalignant cells and lesions by Fordyce, Colleen, Fessenden, Tim, Pickering, Curtis, Jung, Jason, Singla, Veena, Berman, Hal, Tlsty, Thea

“…Cyclooxygenase-2 (COX-2) catalyzes the rate-limiting step in the synthesis of prostaglandins. Its overexpression induces numerous tumor-promoting phenotypes…”
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DNA Damage Drives an Activin A-Dependent Induction of COX-2 in Premalignant Cells and Lesions by Fordyce, Colleen, Fessenden, Tim, Pickering, Curtis, Jung, Jason, Singla, Veena, Berman, Hal, Tlsty, Thea

“…COX-2 catalyzes the rate-limiting step in the synthesis of prostaglandins. Its overexpression induces numerous tumor-promoting phenotypes and is associated…”
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