Search Results - "Fessard, V."

Similar uptake profiles of microcystin-LR and -RR in an in vitro human intestinal model by Zeller, P, Clément, M, Fessard, V

“…Highlights ► First description of in vitro cellular uptake of MCs into intestinal cells. ► OATP 3A1 and OATP 4A1 are expressed in Caco-2 cell membranes. ►…”
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Characterization of aluminum, aluminum oxide and titanium dioxide nanomaterials using a combination of methods for particle surface and size analysis by Krause, B, Meyer, T, Sieg, H, Kästner, C, Reichardt, P, Tentschert, J, Jungnickel, H, Estrela-Lopis, I, Burel, A, Chevance, S, Gauffre, F, Jalili, P, Meijer, J, Böhmert, L, Braeuning, A, Thünemann, A. F, Emmerling, F, Fessard, V, Laux, P, Lampen, A, Luch, A

“…The application of appropriate analytical techniques is essential for nanomaterial (NM) characterization. In this study, we compared different analytical…”
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Genotoxicity and mutagenicity assessment of food contaminant mixtures present in the French diet by Kopp, B., Vignard, J., Mirey, G., Fessard, V., Zalko, D., Le Hgarat, L., Audebert, M.

“…Through diet, people are exposed simultaneously to a variety of contaminants (e.g. heavy metals, mycotoxins, pesticides) that could have combined adverse…”
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The miniaturized enzyme-modified comet assay for genotoxicity testing of nanomaterials by El Yamani, N, Rundén-Pran, E, Collins, A R, Longhin, E M, Elje, E, Hoet, P, Vinković Vrček, I, Doak, S H, Fessard, V, Dusinska, M

“…The comet assay is a widely applied method for investigating genotoxicity of chemicals including engineered nanomaterials (NMs). A big challenge in hazard…”
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Modulation of CYP3A4 activity alters the cytotoxicity of lipophilic phycotoxins in human hepatic HepaRG cells by Ferron, P.J., Hogeveen, K., De Sousa, G., Rahmani, R., Dubreil, E., Fessard, V., Le Hegarat, L.

“…The aim of this study was to investigate (i) the cytotoxic effects of lipophilic phycotoxins, including okadaic acid (OA) and dinophysistoxin-1 and -2 (DTX-1…”
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The PERICLES research program: An integrated approach to characterize the combined effects of mixtures of pesticide residues to which the French population is exposed by Crépet, A, Héraud, F, Béchaux, C, Gouze, M.E, Pierlot, S, Fastier, A, Leblanc, J.Ch, Le Hégarat, L, Takakura, N, Fessard, V, Tressou, J, Maximilien, R, de Sousa, G, Nawaz, A, Zucchini-Pascal, N, Rahmani, R, Audebert, M, Graillot, V, Cravedi, J.P

“…Abstract Due to the broad spectrum of pesticide usages, consumers are exposed to mixtures of residues, which may have combined effects on human health. The…”
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Effects of food chemical contaminants in human HepaRG and Caco-2 cells using an automated microscopy and high content analysis based approach by Ferron, P.-J., Huet, S., Hogeveen, K., Fessard, V., Anses, L. Le Hegarat

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New human intestinal embryonic cell model (HIEC) for toxicity and genotoxicity studies of xenobiotics by Kopp, B., Ferron, P.-J., Fessard, V., Beaulieu, J.-F., Le Hegarat, L.

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Nodularin-induced genotoxicity following oxidative DNA damage and aneuploidy in HepG2 cells by Lankoff, A., Wojcik, A., Fessard, V., Meriluoto, J.

“…The problem of toxicity of Nodularia spumigena to animals and people is of increasing concern, as the incidence of such blooms grows. It was shown that…”
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In vitro combined cytotoxic effects of pesticide mixtures simultaneously found in the French diet by Le Hegarat, L., Takakura, N., Fessard, V.

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Morphological cell transformation of Syrian hamster embryo (SHE) cells by the cyanotoxin, cylindrospermopsin by Maire, M.-A., Bazin, E., Fessard, V., Rast, C., Humpage, A.R., Vasseur, P.

“…Cylindrospermopsin (CYN) is a cyanotoxin which has been implicated in human intoxication and animal mortality. Genotoxic activity of this hepatotoxin is known…”
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4. GdR PHYCOTOX – An interdisciplinary research network on toxic algae, their toxins and their effects on marine ecosystems and society by Hess, P., Hegaret, H., Amzil, Z., Aráoz, R., Dragacci, S., Fessard, V., Guillou, L., Michel-Guillou, E., Molgó, J., Pardo, S., Sechet, V., Siano, R., Soudant, P., Thebault, A.

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Cellular models and cytotoxicity of pinnatoxin-G and extracts of the dinoflagellate Vulcanodinium rugosum recently isolated from the French mediterranean lagoon of Ingril by Geiger, M., Deslanglois, G., Hogeveen, K., Fessard, V., Abadie, E., Leprêtre, T., Hervé, F., Séchet, V., Aráoz, R., Molgó, J., Grovel, O., Pouchus, Y.F., Hess, P.

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Mutagenicity of malachite green and leucomalachite green in in vitro tests by Fessard, V., Godard, T., Huet, S., Mourot, A., Poul, J. M.

“…The genotoxic potential of the fungicide malachite green (MG) and its reduced derivative leucomalachite green (LMG) was assessed in bacteria and mammalian…”
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P19-92 In vitro toxicity assays for investigating the hazard assessment of Bacillus thuringiensis strains by Lanceleur, R., Provost, C., Liuu, S., Pairaud, S., Firmesse, O., Bonis, M., Fessard, V.

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P20-04: Complements on Enniatin B metabolism for interspecies QIVIVE and risk assessment in human by Henri, J., Dubreil, E., Fessard, V., Martin, S., Bree, F., Le Hegarat, L.

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P03-08 Metabolism of Enniatin B in primary mouse, rat and human hepatocytes by Dubreil, E., Ivanova, L., Gendre, C., Mahdjoub, M., Fessard, V., Le Hégarat, L., Faeste, C., Henri, J.

“…Enniatins produced by Fusarium species belong to emerging mycotoxins commonly found in cereals and raising concern for food and feed. They are potentially…”
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P22-21 Combined in silico – in vitro approaches to evaluate mycotoxin toxicity by Habauzit, D., Lemee, P., Huet, S., Alvarino, R., Alfonso, A., Botana, L.M., Hogeveen, K., Fessard, V.

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Characteristics of okadaic acid-induced cytotoxic effects in CHO K1 cells by Huynh-Delerme, C., Fessard, V., Kiefer-Biasizzo, H., Puiseux-Dao, S.

“…This article reports the results of investigations into the process of cell death induced in the Chinese hamster ovary cell K1 subclone (CHO K1) by okadaic…”
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P1-03: A multi-omics strategy to depict and compare the hepatotoxic mechanisms of chlordecone and its metabolite chlordecol by Léger, T., Alilat, S., Dec, L., Hogeveen, K., Ferron, P.-J., Huet, S., Devriendt-Renault, Y., Parinet, J., Fessard, V., Le Hégarat, L.

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