Search Results - "Fertuck, K. C."

Estrogen Receptor-Mediated Actions of Polyphenolic Catechins in Vivo and in Vitro by Goodin, M. G., Fertuck, K. C., Zacharewski, T. R., Rosengren, R. J.

“…Recent investigations have demonstrated that polyphenolic catechins inhibit breast cancer cell proliferation and tumor growth. However, the ER-mediated effects…”
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Interaction of PAH-related compounds with the α and β isoforms of the estrogen receptor by Fertuck, K.C, Kumar, S, Sikka, H.C, Matthews, J.B, Zacharewski, T.R

“…The ability of several 4- and 5-ring polycyclic aromatic hydrocarbons (PAHs), heterocyclic PAHs, and their monohydroxy derivatives to interact with the…”
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Identification of temporal patterns of gene expression in the uteri of immature, ovariectomized mice following exposure to ethynylestradiol by Fertuck, K. C, Eckel, J. E, Gennings, C, Zacharewski, T. R

“…1 Department of Biochemistry and Molecular Biology, and National Food Safety and Toxicology Center, Michigan State University, East Lansing, Michigan 48824 2…”
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Temporal- and dose-dependent hepatic gene expression changes in immature ovariectomized mice following exposure to ethynyl estradiol by Boverhof, D. R., Fertuck, K. C., Burgoon, L. D., Eckel, J. E., Gennings, C., Zacharewski, T. R.

“…Temporal- and dose-dependent changes in hepatic gene expression were examined in immature ovariectomized C57BL/6 mice gavaged with ethynyl estradiol (EE), an…”
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Hydroxylated benzo[a]pyrene metabolites are responsible for in vitro estrogen receptor-mediated gene expression induced by benzo[a]pyrene, but do not elicit uterotrophic effects in vivo by FERTUCK, Kirsten C, MATTHEWS, Jason B, ZACHAREWSKI, Tim R

“…The estrogenic activities of benzo[a]pyrene (B[a]P) and 10 metabolites (1, 3-, 7-, and 9-hydroxy-B[a]P; 4,5-, 7,8-, and 9,10-dihydrodihydroxy-B[a]P; and 1,6-,…”
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Ability of structurally diverse natural products and synthetic chemicals to induce gene expression mediated by estrogen receptors from various species by Matthews, J.B., Fertuck, K.C., Celius, T., Huang, Y.-W., Fong, C.J., Zacharewski, T.R.

“…The ability of 14 structurally diverse estrogenic compounds to induce reporter gene expression mediated by estrogen receptors (ERs) from different species was…”
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Temporal responses to estrogen in the uterus by Fertuck, K. C., Zacharewski, T. R.

“…The estrogen receptor acts primarily as an estrogen-inducible transcription factor in target organs, however, until recently the identification of individual…”
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Use of Xenopus laevis as a model for investigating in vitro and in vivo endocrine disruption in amphibians by Huang, Yue-wern, Matthews, Jason B., Fertuck, Kirsten C., Zacharewski, Tim R.

“…The estrogenic activity of 17β‐estradiol (E2), α‐zearalenol (α‐ZEA), genistein (GEN), and 4‐t‐octylphenol (4‐t‐OP) was investigated using Xenopus laevis‐based…”
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In Silico Approaches to Mechanistic and Predictive Toxicology: An Introduction to Bioinformatics for Toxicologists by Fielden, Mark R., Matthews, Jason B., Fertuck, Kirsten C., Halgren, Robert G., Zacharewski, Tim R.

“…Bioinformatics, or in silico biology, is a rapidly growing field that encompasses the theory and application of computational approaches to model, predict, and…”
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