Search Results - "Ferro, Thomas"

Sp1: Regulation of gene expression by phosphorylation by Chu, Shijian, Ferro, Thomas J.

“…As the prototype of a family of transcription factors, Sp1 has been extensively studied and widely reported for its role in gene regulation. The first evidence…”
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Dupilumab Efficacy in Patients with Type 2 Asthma with and without Elevated Blood Neutrophils by Bleecker, Eugene R., Panettieri, Reynold A., Lugogo, Njira L., Corren, Jonathan, Daizadeh, Nadia, Jacob-Nara, Juby A., Deniz, Yamo, Rowe, Paul J., Khodzhayev, Angela, Soler, Xavier, Ferro, Thomas J., Hansen, Christopher N.

“…Introduction. Elevated neutrophil counts in blood, sputum, or lung have been associated with poor clinical outcomes and more severe disease in patients with…”
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Tezacaftor/ivacaftor in people with cystic fibrosis who stopped lumacaftor/ivacaftor due to respiratory adverse events by Schwarz, Carsten, Sutharsan, Sivagurunathan, Epaud, Ralph, Klingsberg, Ross C., Fischer, Rainald, Rowe, Steven M., Audhya, Paul K., Ahluwalia, Neil, You, Xiaojun, Ferro, Thomas J., Duncan, Margaret E., Bruinsma, Bote G.

“…•Tezacaftor/ivacaftor is not associated with increased respiratory AEs of special interest even in this at-risk population•The safety profile is consistent…”
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Improvements in Psoriasis-Related Work Productivity with Tildrakizumab: Results from a Phase 4 Real-World Study in Patients with Moderate-to-Severe Plaque Psoriasis by Bhutani, Tina, Koo, John, Heim, Jayme, Bhatia, Neal, Mathew, Jacob, Ferro, Thomas, Vasquez, J. Gabriel

“…Introduction Plaque psoriasis is a chronic condition that may impact patients’ work productivity. Tildrakizumab, an interleukin-23 p19 inhibitor, is approved…”
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The impact of expired and empty quick-relief asthma inhalers: The Asthma and Allergy Foundation of America's Asthma Inhaler Design Survey by Storms, William W, Tringale, Mike, Ferro, Thomas J

“…Despite the available treatments, asthma remains a serious illness, with a considerable socioeconomic burden associated with a high number of unscheduled…”
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Racial and Ethnic Minorities at the Highest Risk of Uncontrolled Moderate-to-Severe Asthma: A United States Electronic Health Record Analysis by George, Maureen, Camargo, Jr, Carlos A, Burnette, Autumn, Chen, Yuning, Pawar, Ajinkya, Molony, Cliona, Auclair, Melissa, Wells, Michael A, Ferro, Thomas J

“…The identification of risk factors associated with uncontrolled moderate-to-severe asthma is important to improve asthma outcomes. Aim of this study was to…”
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Fluticasone propionate/salmeterol 250/50 μg versus salmeterol 50 μg after chronic obstructive pulmonary disease exacerbation by Ohar, Jill A, Crater, Glenn D, Emmett, Amanda, Ferro, Thomas J, Morris, Andrea N, Raphiou, Ibrahim, Sriram, Peruvemba S, Dransfield, Mark T

“…Inhaled long-acting beta2 agonists used alone and in combination with an inhaled corticosteroid reduce the risk of exacerbations in patients with stable COPD…”
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Identification of a hydrogen peroxide-induced PP1-JNK1-Sp1 signaling pathway for gene regulation by Chu, Shijian, Ferro, Thomas J

“…Oxidative stress often results in changes in gene expression through the regulation of transcription factors. In this study, we examine how Sp1 phosphorylation…”
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Effect of fluticasone propionate/salmeterol plus tiotropium versus tiotropium on walking endurance in COPD by Maltais, François, Mahler, Donald A, Pepin, Véronique, Nadreau, Eric, Crater, Glenn D, Morris, Andrea N, Emmett, Amanda H, Ferro, Thomas J

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Body Mass Index and Response to Asthma Therapy: Fluticasone Propionate/Salmeterol versus Montelukast by Camargo, Carlos A., Boulet, Louis-Philippe, Sutherland, E. Rand, Busse, William W., Yancey, Steven W., Emmett, Amanda H., Ortega, Hector G., Ferro, Thomas J.

“…We studied the relationship between body mass index (BMI) on responses to asthma therapy using a retrospective analysis of four previously reported clinical…”
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Comparing Ran-Out Status of Inhaled Short-Acting Beta-Agonists in Emergency Department Patients with Acute Asthma: 1996-1998 versus 2015-2017 by Goto, Tadahiro, Camargo, Carlos A., Gimenez-Zapiola, Catalina, Pallin, Daniel J., Shapiro, Nathan I., Ferro, Thomas J., Rainville, Carolyn, Stoyanov, Stanislav, Hasegawa, Kohei

“…Medication nonadherence, including running out of inhaled asthma medications, is an important problem. The objective of this study was to examine the changes…”
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Historical cohort study examining comparative effectiveness of albuterol inhalers with and without integrated dose counter for patients with asthma or chronic obstructive pulmonary disease by Price, David B, Rigazio, Anna, Buatti Small, Mary, Ferro, Thomas J

“…Using a metered-dose inhaler (MDI) beyond the labeled number of actuations may result in inadequate dosing of medication, which can lead to poor clinical…”
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Poly(ADP-ribose) polymerase-1 regulates vimentin expression in lung cancer cells by Chu, Shijian, Xu, Haishan, Ferro, Thomas J, Rivera, Paola X

“…Vimentin is one of the mammalian intermediate filament proteins. It is expressed in cells of mesenchymal origin and is characteristic of proliferating cells at…”
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Real-world health care utilization in asthma patients using albuterol sulfate inhalation aerosol (ProAir ® HFA) with and without integrated dose counters by Kerwin, Edward M, Ferro, Thomas J, Ariely, Rinat, Irwin, Debra E, Parikh, Ruchir

“…Accurate tracking of the administered dose of asthma rescue inhalers is critical for optimal disease management and is related to reductions in rates of…”
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Real-world healthcare utilization in asthma patients using albuterol sulfate inhalation aerosol (ProAir® HFA) with and without integrated dose counters by Kerwin, Edward, Ferro, Thomas J., Ariely, Rinat, Irwin, Debra, Parikh, Ruchir

“…Background: Accurate tracking of the administered dose of asthma rescue inhalers is critical for optimal disease management and is related to reductions in…”
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Disappearance of microalbuminuria in a patient with type 2 diabetes and the metabolic syndrome in the setting of an intense exercise and dietary program with sustained weight reduction by FREDRICKSON, Sonja K, FERRO, Thomas J, SCHUTRUMPF, Andrew C

“…Fredrickson et al performed a study on a patient with the metabolic syndrome who demonstrated with microalbuminuria and treated with an intensive regimen of…”
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Overview of national treatment guidelines for common respiratory tract infections by Ferro, Thomas J

“…CAP, ABECB, and AOM are common community-acquired infections accounting for many office visits and many prescriptions for antibacterial agents. In addition,…”
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Expression of α-ENaC2 is dependent on an upstream Sp1 binding motif and is modulated by protein phosphatase 1 in lung epithelial cells by Chu, Shijian, Cockrell, Charlotte A., Ferro, Thomas J.

“…The amiloride-sensitive Na + channel ENaC is expressed in lung epithelium and plays a pivotal role in lung fluid clearance in the newborn. Multiple splice…”
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Interferon-γ regulates ClC-2 chloride channel in lung epithelial cells by Chu, Shijian, Blaisdell, Carol J., Bamford, Penelope, Ferro, Thomas J.

“…Epithelial Cl − channels mediate Cl − and fluid secretion in the lung. In cystic fibrosis, aberrant Cl − secretion is one of the major causes for lung fluid…”
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The Treatment of Community-Acquired Pneumonia: A Brief Overview of the National Guidelines by Ferro, Thomas J

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