Search Results - "Ferris, K. K."
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BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation
Published in Nature (London) (22-06-2017)“…BRCA1-associated protein 1 (BAP1) regulates calcium flux in the endoplasmic reticulum to facilitate the execution of apoptosis, unveiling a new facet of the…”
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Anti–IL-23A mAb BI 655066 for treatment of moderate-to-severe psoriasis: Safety, efficacy, pharmacokinetics, and biomarker results of a single-rising-dose, randomized, double-blind, placebo-controlled trial
Published in Journal of allergy and clinical immunology (01-07-2015)“…Background IL-23 is associated with plaque psoriasis susceptibility and pathogenesis. BI 655066 is a fully human IgG1 mAb specific for the IL-23 p19 subunit…”
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Diagnostic inaccuracy of smartphone applications for melanoma detection
Published in JAMA dermatology (Chicago, Ill.) (01-04-2013)“…To measure the performance of smartphone applications that evaluate photographs of skin lesions and provide the user with feedback about the likelihood of…”
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Computer-aided classification of melanocytic lesions using dermoscopic images
Published in Journal of the American Academy of Dermatology (01-11-2015)“…Background Computer-assisted diagnosis of dermoscopic images of skin lesions has the potential to improve melanoma early detection. Objective We sought to…”
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Brain and Body: A Review of Central Nervous System Contributions to Movement Impairments in Diabetes
Published in Diabetes (New York, N.Y.) (01-01-2020)“…Diabetes is associated with a loss of somatosensory and motor function, leading to impairments in gait, balance, and manual dexterity. Data-driven neuroimaging…”
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Development and validation of a noninvasive 2-gene molecular assay for cutaneous melanoma
Published in Journal of the American Academy of Dermatology (01-01-2017)“…Background Clinical and histopathologic assessment of pigmented skin lesions remains challenging even for experts. Differentiated and accurate noninvasive…”
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A Review of Transcranial Magnetic Stimulation and Multimodal Neuroimaging to Characterize Post-Stroke Neuroplasticity
Published in Frontiers in neurology (29-10-2015)“…Following stroke, the brain undergoes various stages of recovery where the central nervous system can reorganize neural circuitry (neuroplasticity) both…”
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Improved processing speed and decreased functional connectivity in individuals with chronic stroke after paired exercise and motor training
Published in Scientific reports (22-08-2023)“…After stroke, impaired motor performance is linked to an increased demand for cognitive resources. Aerobic exercise improves cognitive function in…”
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Performance of a prognostic 31-gene expression profile in an independent cohort of 523 cutaneous melanoma patients
Published in BMC cancer (05-02-2018)“…The heterogeneous behavior of patients with melanoma makes prognostication challenging. To address this, a gene expression profile (GEP) test to predict…”
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Short and long-term safety outcomes with ixekizumab from 7 clinical trials in psoriasis: Etanercept comparisons and integrated data
Published in Journal of the American Academy of Dermatology (01-03-2017)“…Background Safety of biologics is important when treating patients with psoriasis. Objective We sought to determine the safety of ixekizumab in psoriasis…”
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Gene expression profiling for molecular staging of cutaneous melanoma in patients undergoing sentinel lymph node biopsy
Published in Journal of the American Academy of Dermatology (01-05-2015)“…Background A gene expression profile (GEP) test able to accurately identify risk of metastasis for patients with cutaneous melanoma has been clinically…”
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Identification of high-risk cutaneous melanoma tumors is improved when combining the online American Joint Committee on Cancer Individualized Melanoma Patient Outcome Prediction Tool with a 31-gene expression profile–based classification
Published in Journal of the American Academy of Dermatology (01-05-2017)“…Background A significant proportion of patients with American Joint Committee on Cancer (AJCC)-defined early-stage cutaneous melanoma have disease recurrence…”
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COVID-19 vaccine safety and efficacy in patients with immune-mediated inflammatory disease: Review of available evidence
Published in Journal of the American Academy of Dermatology (01-11-2021)“…Dermatologists diagnose and treat many immune-mediated inflammatory diseases (IMID). Understanding the inherent immune dysregulation of these diseases as well…”
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Efficacy and Safety of Ixekizumab Through 5 Years in Moderate-to-Severe Psoriasis: Long-Term Results from the UNCOVER-1 and UNCOVER-2 Phase-3 Randomized Controlled Trials
Published in Dermatology and therapy (01-06-2020)“…Introduction Ixekizumab, a high-affinity monoclonal antibody that selectively targets interleukin-17A, is approved for treatment of moderate-to-severe plaque…”
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Pharmacokinetics, safety, and efficacy of cedirogant from phase I studies in healthy participants and patients with chronic plaque psoriasis
Published in Clinical and translational science (01-01-2024)“…Cedirogant is an inverse agonist of retinoic acid‐related orphan receptor gamma thymus (RORγt) developed for the treatment of moderate to severe chronic plaque…”
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Severity-Mapped Vibrotactile Cues to Support Interruption Management with Weather Messaging in the General Aviation Cockpit
Published in Atmosphere (01-03-2021)“…Despite the increasing availability of technologies that provide access to aviation weather information in the cockpit, weather remains a prominent contributor…”
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Interhemispheric Pathways Are Important for Motor Outcome in Individuals with Chronic and Severe Upper Limb Impairment Post Stroke
Published in Neural plasticity (01-01-2017)“…Background. Severity of arm impairment alone does not explain motor outcomes in people with severe impairment post stroke. Objective. Define the contribution…”
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Electrophilic nitro-fatty acids suppress psoriasiform dermatitis: STAT3 inhibition as a contributory mechanism
Published in Redox biology (01-07-2021)“…Psoriasis is a chronic inflammatory skin disease with no cure. Although the origin of psoriasis and its underlying pathophysiology remain incompletely…”
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Teledermatology isotretinoin management for moderate-to-severe acne reveals similar outcomes to in-person management: A retrospective study
Published in JAAD international (01-06-2023)Get full text
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