Are There Height‐Dependent Differences in Subclinical Vascular Disease in Hypertensive Patients?

The aim of the study was to determine whether there are differences in subclinical vascular disease (SVD) in hypertensive patients in relation to height. A total of 922 hypertensive, newly diagnosed, treatment‐naive patients were included. Physical examination was conducted, with renal function, ele...

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Bibliographic Details
Published in:	The journal of clinical hypertension (Greenwich, Conn.) Vol. 16; no. 1; pp. 70 - 76
Main Authors:	Ferriol, Caterina, Tremols, Susanna, Jimenez, Carmen, Tura, Anna, Sanmartín, Maria, Pagès, Núria, Rodríguez‐Poncelas, Antonio, Paz‐Bermejo, Marco, Saez, Marc, Coll‐de‐Tuero, Gabriel
Format:	Journal Article
Language:	English
Published:	United States John Wiley and Sons Inc 01-01-2014
Subjects:	Aged Body Height - physiology Body Mass Index Female Humans Hypertension - complications Hypertension - physiopathology Hypertensive Retinopathy - epidemiology Hypertrophy, Left Ventricular - epidemiology Male Middle Aged Multivariate Analysis Original Paper Original Papers Prevalence Prospective Studies Risk Factors Sex Factors Vascular Diseases - epidemiology
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Summary:	The aim of the study was to determine whether there are differences in subclinical vascular disease (SVD) in hypertensive patients in relation to height. A total of 922 hypertensive, newly diagnosed, treatment‐naive patients were included. Physical examination was conducted, with renal function, electrocardiography, and retinography. Patients were distributed according to quartiles of height and sex. Multivariate analysis adjusted for age, sex, and body mass index showed an association between height above the mean and fasting glucose (odds ratio [OR], 1.04; 95% confidence interval [CI], 1.02–1.06), high‐density lipoprotein cholesterol (OR, 0.96; CI, 0.92–0.99), triglycerides (OR, 1.07; CI, 1.01–1.15), and left ventricular hypertrophy (LVH) (OR, 1.57; CI, 1.10–2.24). The authors found an inverse association between arteriole‐to‐venule ratio and height above the mean (OR, 0.97; CI, 0.94–0.99). There are differences in the SVD of hypertensive patients in relation to height. Tall stature is associated with LVH while short stature is associated with increased microvascular involvement. Detection of SVD in hypertensive patients should consider the height.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1524-6175 1751-7176
DOI:	10.1111/jch.12222