Search Results - "Ferrins, Lori"

Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2 by Sanders, Brian C., Pokhrel, Suman, Labbe, Audrey D., Mathews, Irimpan I., Cooper, Connor J., Davidson, Russell B., Phillips, Gwyndalyn, Weiss, Kevin L., Zhang, Qiu, O’Neill, Hugh, Kaur, Manat, Schmidt, Jurgen G., Reichard, Walter, Surendranathan, Surekha, Parvathareddy, Jyothi, Phillips, Lexi, Rainville, Christopher, Sterner, David E., Kumaran, Desigan, Andi, Babak, Babnigg, Gyorgy, Moriarty, Nigel W., Adams, Paul D., Joachimiak, Andrzej, Hurst, Brett L., Kumar, Suresh, Butt, Tauseef R., Jonsson, Colleen B., Ferrins, Lori, Wakatsuki, Soichi, Galanie, Stephanie, Head, Martha S., Parks, Jerry M.

“…Direct-acting antivirals are needed to combat coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome-coronavirus-2…”
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Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides by Russell, Stephanie, Rahmani, Raphaël, Jones, Amy J, Newson, Harriet L, Neilde, Kevin, Cotillo, Ignacio, Rahmani Khajouei, Marzieh, Ferrins, Lori, Qureishi, Sana, Nguyen, Nghi, Martinez-Martinez, Maria S, Weaver, Donald F, Kaiser, Marcel, Riley, Jennifer, Thomas, John, De Rycker, Manu, Read, Kevin D, Flematti, Gavin R, Ryan, Eileen, Tanghe, Scott, Rodriguez, Ana, Charman, Susan A, Kessler, Albane, Avery, Vicky M, Baell, Jonathan B, Piggott, Matthew J

“…The parasitic trypanosomes Trypanosoma brucei and T. cruzi are responsible for significant human suffering in the form of human African trypanosomiasis (HAT)…”
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A diverse view of science to catalyse change by Urbina-Blanco, César A., Jilani, Safia Z., Speight, Isaiah R., Bojdys, Michael J., Friščić, Tomislav, Stoddart, J. Fraser, Nelson, Toby L., Mack, James, Robinson, Renã A. S., Waddell, Emanuel A., Lutkenhaus, Jodie L., Godfrey, Murrell, Abboud, Martine I., Aderinto, Stephen O., Aderohunmu, Damilola, Bibič, Lučka, Borges, João, Dong, Vy M., Ferrins, Lori, Fung, Fun Man, John, Torsten, Lim, Felicia P. L., Masters, Sarah L., Mambwe, Dickson, Thordarson, Pall, Titirici, Maria-Magdalena, Tormet-González, Gabriela D., Unterlass, Miriam M., Wadle, Austin, Yam, Vivian W.-W., Yang, Ying-Wei

“…Valuing diversity leads to scientific excellence, the progress of science and, most importantly, it is simply the right thing to do. We must value diversity…”
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Hypothesis-generating proteome perturbation to identify NEU-4438 and acoziborole modes of action in the African Trypanosome by Sharma, Amrita, Cipriano, Michael, Ferrins, Lori, Hajduk, Stephen L., Mensa-Wilmot, Kojo

“…NEU-4438 is a lead for the development of drugs against Trypanosoma brucei, which causes human African trypanosomiasis. Optimized with phenotypic screening,…”
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Drug discovery and human African trypanosomiasis: a disease less neglected? by Ferrins, Lori, Rahmani, Raphaël, Baell, Jonathan B

“…Human African trypanosomiasis (HAT) has been neglected for a long time. The most recent drug to treat this disease, eflornithine, was approved by the US FDA in…”
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Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes by Ferrins, Lori, Buskes, Melissa J, Kapteyn, Madison M, Engels, Hannah N, Enos, Suzanne E, Lu, Chenyang, Klug, Dana M, Singh, Baljinder, Quotadamo, Antonio, Bachovchin, Kelly, Tear, Westley F, Spaulding, Andrew E, Forbes, Katherine C, Bag, Seema, Rivers, Mitch, LeBlanc, Catherine, Burchfield, Erin, Armand, Jeremy R, Diaz-Gonzalez, Rosario, Ceballos-Perez, Gloria, García-Hernández, Raquel, Pérez-Moreno, Guiomar, Bosch-Navarrete, Cristina, Ruiz-Pérez, Luis Miguel, Gamarro, Francisco, González-Pacanowska, Dolores, Navarro, Miguel, Mensa-Wilmot, Kojo, Pollastri, Michael P, Kyle, Dennis E, Rice, Christopher A

“…species, , and are opportunistic pathogens that cause a range of brain, skin, eye, and disseminated diseases in humans and animals. These pathogenic…”
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Corrigendum: Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes by Ferrins, Lori, Buskes, Melissa J., Kapteyn, Madison M., Engels, Hannah N., Enos, Suzanne E., Lu, Chenyang, Klug, Dana M., Singh, Baljinder, Quotadamo, Antonio, Bachovchin, Kelly, Tear, Westley F., Spaulding, Andrew E., Forbes, Katherine C., Bag, Seema, Rivers, Mitch, LeBlanc, Catherine, Burchfield, Erin, Armand, Jeremy R., Diaz-Gonzalez, Rosario, Ceballos-Perez, Gloria, García-Hernández, Raquel, Pérez-Moreno, Guiomar, Bosch-Navarrete, Cristina, Gómez-Liñán, Claudia, Ruiz-Pérez, Luis Miguel, Gamarro, Francisco, González-Pacanowska, Dolores, Navarro, Miguel, Mensa-Wilmot, Kojo, Pollastri, Michael P., Kyle, Dennis E., Rice, Christopher A.

“…[This corrects the article DOI: 10.3389/fmicb.2023.1149145.]…”
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Anilinoquinoline based inhibitors of trypanosomatid proliferation by Ferrins, Lori, Sharma, Amrita, Thomas, Sarah M, Mehta, Naimee, Erath, Jessey, Tanghe, Scott, Leed, Susan E, Rodriguez, Ana, Mensa-Wilmot, Kojo, Sciotti, Richard J, Gillingwater, Kirsten, Pollastri, Michael P

“…We recently reported the medicinal chemistry re-optimization of a series of compounds derived from the human tyrosine kinase inhibitor, lapatinib, for activity…”
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Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents by Klug, Dana M, Diaz-Gonzalez, Rosario, Pérez-Moreno, Guiomar, Ceballos-Pérez, Gloria, García-Hernández, Raquel, Gomez-Pérez, Veronica, Ruiz-Pérez, Luis Miguel, Rojas-Barros, Domingo I, Gamarro, Francisco, González-Pacanowska, Dolores, Martínez-Martínez, María S, Manzano, Pilar, Ferrins, Lori, Caffrey, Conor R, Navarro, Miguel, Pollastri, Michael P

“…New treatments are needed for neglected tropical diseases (NTDs) such as Human African trypanosomiasis (HAT), Chagas disease, and schistosomiasis. Through a…”
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Call for Papers: Exploring Covalent Modulators in Drug Discovery and Chemical Biology by Ferrins, Lori, Adams, Ashley

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Call for Papers: The Many Faces of Medicinal Chemistry by Ferrins, Lori, Adams, Ashley

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Call for Papers: Exploring Covalent Modulators in Drug Discovery and Chemical Biology by Ferrins, Lori, Adams, Ashley

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Call for Papers: The Many Faces of Medicinal Chemistry by Ferrins, Lori, Adams, Ashley

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Call for Papers: Exploring Covalent Modulators in Drug Discovery and Chemical Biology by Ferrins, Lori, Adams, Ashley

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Highlighting the 2020–2021 ACS Division of Medicinal Chemistry Award Winners by Ferrins, Lori, Schwarz, Jacob B.

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Stakeholders’ Thoughts on the Future of IUPAC: Update on the IUPAC Organizational Structure Review project by Ferrins, Lori, Chao, Ito, Cesa, Mark

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YMCC and YSN: An Opportunity for Scientific and Cultural Exchange by Ferrins, Lori, Olson, Margaret E., Haranahalli, Krupanandan, Grenier-Davies, Melissa C., Boudreau, Matthew W., Matagne, Brieuc, Donckele, Etienne J., Borsari, Chiara

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Nuisance compounds in cellular assays by Dahlin, Jayme L, Auld, Douglas S, Rothenaigner, Ina, Haney, Steve, Sexton, Jonathan Z, Nissink, J Willem M, Walsh, Jarrod, Lee, Jonathan A, Strelow, John M, Willard, Francis S, Ferrins, Lori, Baell, Jonathan B, Walters, Michael A, Hua, Bruce K, Hadian, Kamyar, Wagner, Bridget K

“…Compounds that exhibit assay interference or undesirable mechanisms of bioactivity ("nuisance compounds") are routinely encountered in cellular assays,…”
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Excellence in Medicinal Chemistry: Celebrating ACS Medicinal Chemistry Division (MEDI) Awards. A Call for Nominations by Blanco, Maria-Jesus, Bryant-Friedrich, Amanda, Georg, Gunda, Ali, Amjad, Ornstein, Paul L., Ferrins, Lori

“…The American Chemical Society Division of Medicinal Chemistry (MEDI) confers a range of awards, fellowships and honors to recognize excellence in medicinal…”
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Engaging the Medicinal Chemists of Tomorrow by Ferrins, Lori, Araujo, Erika, Boudreau, Matthew W, Grenier-Davies, Melissa C, Haranahalli, Krupanandan, Journigan, V Blair, Klug, Dana M, Olson, Margaret E

“…The Young Medicinal Chemists Committee (YMCC) is a part of the larger ACS Division of Medicinal Chemistry (MEDI) and was formed to ensure that MEDI meets the…”
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