Search Results - "Ferreira Teixeira, Helder"

Recent Patents Concerning the use of Nanotechnology-based Delivery Systems as Skin Penetration Enhancers by Medeiros-Neves, Bruna, Nemitz, Marina Cardoso, Silveira Fachel, Flávia Nathiely, Teixeira, Helder Ferreira

“…Nanotechnology-based delivery systems have been considered a promising approach for topical application, considering their characteristics of penetration…”
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Quantification of Coumarins in Aqueous Extract of Pterocaulon balansae (Asteraceae) and Characterization of a New Compound by Medeiros-Neves, Bruna, de Barros, Francisco Maikon Corrêa, von Poser, Gilsane Lino, Teixeira, Helder Ferreira

“…Plants from the genus Pterocaulon are popularly used as antifungal and wound-healing agents. Such activities have been related to coumarins, which are abundant…”
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Box-Behnken design optimization of mucoadhesive chitosan-coated nanoemulsions for rosmarinic acid nasal delivery—In vitro studies by Fachel, Flávia Nathiely Silveira, Medeiros-Neves, Bruna, Dal Prá, Morgana, Schuh, Roselena Silvestri, Veras, Kleyton Santos, Bassani, Valquíria Linck, Koester, Letícia Scherer, Henriques, Amelia Teresinha, Braganhol, Elizandra, Teixeira, Helder Ferreira

“…[Display omitted] •Chitosan-coated RA nanoemulsion was successfully optimized using Box-Behnken design.•Mucoadhesive potential from chitosan-coated RA…”
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In vivo genome editing of mucopolysaccharidosis I mice using the CRISPR/Cas9 system by Schuh, Roselena Silvestri, Poletto, Édina, Pasqualim, Gabriela, Tavares, Angela Maria Vicente, Meyer, Fabíola Shons, Gonzalez, Esteban Alberto, Giugliani, Roberto, Matte, Ursula, Teixeira, Helder Ferreira, Baldo, Guilherme

“…Mucopolysaccharidosis type I (MPS I) is a multisystemic disorder caused by the deficiency of alpha-L-iduronidase (IDUA) that leads to intracellular…”
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Laronidase-loaded liposomes reach the brain and other hard-to-treat organs after noninvasive nasal administration by Schuh, Roselena Silvestri, Franceschi, Eduarda Piovesan, Brum, Bruna Brazeiro, Fachel, Flávia Nathiely Silveira, Poletto, Édina, Vera, Luisa Natália Pimentel, Santos, Hallana Souza, Medeiros-Neves, Bruna, Monteagudo de Barros, Vinicius, Helena da Rosa Paz, Ana, Baldo, Guilherme, Matte, Ursula, Giugliani, Roberto, Ferreira Teixeira, Helder

“…[Display omitted] •Liposomal laronidase formulation was successfully developed.•Laronidase-loaded liposomes promoted an increase in enzyme activity in…”
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On the use of nanotechnology-based strategies for association of complex matrices from plant extracts by Zorzi, Giovanni Konat, Carvalho, Edison Luis Santana, von Poser, Gilsane Lino, Teixeira, Helder Ferreira

“…Depending on the method of extraction, plant extracts can contain an enormous variety of active molecules, such as phenolic compounds, essential oils,…”
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Supercritical Carbon Dioxide Extraction of Coumarins from the Aerial Parts of Pterocaulon polystachyum by Scopel, Júlia M, Medeiros-Neves, Bruna, Teixeira, Helder Ferreira, Brazil, Nathalya T, Bordignon, Sérgio A L, Diz, Fernando Mendonça, Morrone, Fernanda Bueno, Almeida, Rafael N, Cassel, Eduardo, von Poser, Gilsane L, Vargas, Rubem M F

“…is a species of pharmacological interest for providing volatile and non-volatile extracts with antifungal and amebicidal properties. The biological activities…”
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Nasal Administration of Cationic Nanoemulsions as Nucleic Acids Delivery Systems Aiming at Mucopolysaccharidosis Type I Gene Therapy by Schuh, Roselena Silvestri, Bidone, Juliana, Poletto, Edina, Pinheiro, Camila Vieira, Pasqualim, Gabriela, de Carvalho, Talita Giacomet, Farinon, Mirian, da Silva Diel, Dirnete, Xavier, Ricardo Machado, Baldo, Guilherme, Matte, Ursula, Teixeira, Helder Ferreira

“…Purpose This study demonstrates the nasal administration (NA) of nanoemulsions complexed with the plasmid encoding for IDUA protein (pIDUA) as an attempt to…”
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Glioprotective Effect of Chitosan-Coated Rosmarinic Acid Nanoemulsions Against Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Rat Astrocyte Primary Cultures by Fachel, Flávia Nathiely Silveira, Dal Prá, Morgana, Azambuja, Juliana Hofstätter, Endres, Marcelo, Bassani, Valquíria Linck, Koester, Letícia Scherer, Henriques, Amelia Teresinha, Barschak, Alethea Gatto, Teixeira, Helder Ferreira, Braganhol, Elizandra

“…Rosmarinic acid (RA) is a natural polyphenolic compound with a well-documented neuroprotective effect mainly associated with its anti-inflammatory and…”
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Development, physico‐chemical characterization and in‐vitro studies of hydrogels containing rosmarinic acid‐loaded nanoemulsion for topical application by Marafon, Paula, Fachel, Flávia Nathiely Silveira, Dal Prá, Morgana, Bassani, Valquíria Linck, Koester, Letícia Scherer, Henriques, Amélia Teresinha, Braganhol, Elizandra, Teixeira, Helder Ferreira

“…Objectives Natural sources with antioxidant activity, such as rosmarinic acid (RA), have been considered as an interesting approach for the development of new…”
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Development of Nasal Lipid Nanocarriers Containing Curcumin for Brain Targeting by Vaz, Gustavo Richter, Hädrich, Gabriela, Bidone, Juliana, Rodrigues, Jamile Lima, Falkembach, Mariana Corrêa, Putaux, Jean-Luc, Hort, Mariana Appel, Monserrat, José Maria, Varela Junior, Antônio Sergio, Teixeira, Helder Ferreira, Muccillo-Baisch, Ana Luiza, Horn, Ana Paula, Dora, Cristiana Lima

“…Curcumin (CUR) has properties that can be useful for the treatment of Alzheimer's disease. Such properties are the inhibition of amyloid-β-protein (Aβ)…”
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Cyclodextrin-Based Delivery Systems and Hydroxycinnamic Acids: Interactions and Effects on Crucial Parameters Influencing Oral Bioavailability-A Review by Veras, Kleyton Santos, Fachel, Flávia Nathiely Silveira, Bassani, Valquiria Linck, Teixeira, Helder Ferreira, Koester, Letícia Scherer

“…Hydroxycinnamic acids (HCAs) are a subclass of phenolic acids presenting caffeic acid (CA), chlorogenic acid (CGA), coumaric acid (COA) isomers, ferulic acid…”
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A stability‐indicating ultra‐fast liquid chromatography method for the assay of the main flavonoids of Achyrocline satureioides (Marcela) in porcine skin layers and nanoemulsions by Balestrin, Lucélia Albarello, Fachel, Flávia Nathiely Silveira, Koester, Letícia Scherer, Bassani, Valquiria Linck, Teixeira, Helder Ferreira

“…Introduction Achyrocline satureioides (marcela or macela) is a plant widely used in folk medicine in South America. Recently, there has been increasing…”
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Oral Pharmacokinetics of Hydroxycinnamic Acids: An Updated Review by Veras, Kleyton Santos, Fachel, Flávia Nathiely Silveira, de Araújo, Bibiana Verlindo, Teixeira, Helder Ferreira, Koester, Letícia Scherer

“…Hydroxycinnamic acids (HCAs) such as caffeic acid (CA), chlorogenic acid (CGA), coumaric acid (COA) isomers, ferulic acid (FA) and rosmarinic acid (RA) are…”
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The international scenario of patents concerning isoflavones by Nemitz, Marina Cardoso, Argenta, Débora Fretes, Koester, Letícia Scherer, Bassani, Valquíria Linck, von Poser, Gilsane Lino, Teixeira, Helder Ferreira

“…Isoflavones are a class of phytoestrogens that has been considered important raw material for healthcare products, mainly as dietary supplements for hormone…”
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Bioactive soy isoflavones: extraction and purification procedures, potential dermal use and nanotechnology-based delivery systems by Nemitz, Marina Cardoso, Moraes, Renata Cougo, Koester, Letícia Scherer, Bassani, Valquiria Linck, von Poser, Gilsane Lino, Teixeira, Helder Ferreira

“…Isoflavones are polyphenol compounds found mainly in legumes such as soybeans ( Glycine max (L.) Merrill). These compounds can be found in different chemical…”
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Compatibility study of rosmarinic acid with excipients used in pharmaceutical solid dosage forms using thermal and non-thermal techniques by Veras, Kleyton Santos, Fachel, Flávia Nathiely Silveira, Pittol, Vanessa, Garcia, Keth Ribeiro, Bassani, Valquíria Linck, dos Santos, Venina, Henriques, Amélia Teresinha, Teixeira, Helder Ferreira, Koester, Letícia Scherer

“…Rosmarinic acid (RA) is a phenolic compound that presents well-documented anti-inflammatory, antioxidant and antitumor activities, and based on its…”
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Achyrocline satureioides (Lam.) DC (Asteraceae) Extract-Loaded Nanoemulsions as a Promising Topical Wound Healing Delivery System: In Vitro Assessments in Human Keratinocytes (HaCaT) and HET-CAM Irritant Potential by Balestrin, Lucélia Albarello, Kreutz, Tainá, Fachel, Flávia Nathiely Silveira, Bidone, Juliana, Gelsleichter, Nicolly Espindola, Koester, Letícia Scherer, Bassani, Valquiria Linck, Braganhol, Elizandra, Dora, Cristiana Lima, Teixeira, Helder Ferreira

“…Achyrocline satureioides (Lam.) DC Asteraceae extracts (ASEs) have been investigated for the treatment of various skin disorders. This study reports the…”
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Gene Therapy of Mucopolysaccharidosis Type I Mice: Repeated Administrations and Safety Assessment of pIDUA/Nanoemulsion Complexes by Fraga, Michelle, Schuh, Roselena Silvestri, Poletto, Édina, de Carvalho, Talita Giacomet, França, Raqueli Teresinha, Pinheiro, Camila Vieira, Baldo, Gilherme, Giugliani, Roberto, Teixeira, Helder Ferreira, Matte, Ursula

“…Mucopolysaccharidosis type I (MPS I) is an inherited disorder caused by α-L-iduronidase (IDUA) deficiency. The available treatments are not effective in…”
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Piper aduncum Essential Oil Rich in Dillapiole: Development of Hydrogel-Thickened Nanoemulsion and Nanostructured Lipid Carrier Intended for Skin Delivery by Carneiro, Simone Braga, Kreutz, Tainá, Limberger, Renata Pereira, Teixeira, Helder Ferreira, da Veiga Júnior, Valdir Florêncio, Koester, Letícia Scherer

“…The essential oil extracted from the leaves of Piper aduncum, an aromatic plant from the Amazon region, is rich in dillapiole and presents anti-inflammatory…”
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