Search Results - "Ferreira Oliveira, Maria Conceição"

Resolution of Racemic Aryloxy-Propan-2-yl Acetates via Lipase-Catalyzed Hydrolysis: Preparation of Enantiomerically Pure/Enantioenriched Mexiletine Intermediates and Analogs by Ana Caroline Lustosa de Melo Carvalho, Bruna Rocha de Oliveira, Gledson Vieira Lima, Jonatas Martins Negreiro, Maria Conceição Ferreira Oliveira, Telma Leda Gomes de Lemos, Marcos Reinaldo da Silva, Thiago de Sousa Fonseca, Rayanne Mendes Bezerra, Jose Cleiton Sousa dos Santos, Luciana Rocha Barros Gonçalves, Nathalia Saraiva Rios, Geancarlo Zanatta, Marcos Carlos de Mattos

“…The lipase kinetic resolution (KR) of aryloxy-propan-2-yl acetates, via hydrolysis, produced enantiomerically pure/enantioenriched mexiletine intermediates and…”
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The Isoflavanoid (+)‐PTC Regulates Cell‐Cycle Progression and Mitotic Spindle Assembly in a Prostate Cancer Cell Line by Moraes de Farias, Kaio, Rosa‐Ribeiro, Rafaela, Souza, Edmarcia E., Kobarg, Jörg, Banwell, Martin G., Brito Vieira Neto, José, Leyenne Alves Sales, Sarah, Roberto Ribeiro Costa, Paulo, Cavalcante dos Santos, Rafael, Vilaça Gaspar, Francisco, Gomes Barreto Junior, Amaro, Conceição Ferreira Oliveira, Maria, Odorico de Moraes, Manoel, Libardi M. Furtado, Cristiana, Carvalho, Hernandes F., Pessoa, Claudia

“…Prostate cancer is the second most common malignancy in men and the development of effective therapeutic strategies remains challenging when more advanced,…”
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Synthesis and in vitro antifungal activity of isoniazid-derived hydrazones against Coccidioides posadasii by Cordeiro, Rossana de Aguiar, de Melo, Charlline Vládia Silva, Marques, Francisca Jakelyne de Farias, Serpa, Rosana, Evangelista, Antônio José de Jesus, Caetano, Erica Pacheco, Mafezoli, Jair, de Oliveira, Maria da Conceição Ferreira, da Silva, Marcos Reinaldo, Bandeira, Tereza de Jesus Pinheiro Gomes, Moreira, José Luciano Bezerra, Brilhante, Raimunda Sâmia Nogueira, Rocha, Marcos Fábio Gadelha, Sidrim, José Júlio Costa

“…Coccidioidomycosis is a potentially severe infection caused by dimorphic fungi Coccidioides immitis and Coccidioides posadasii. Although guidelines are well…”
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Chemical modification of clay nanocomposites for the improvement of the catalytic properties of Lipase A from Candida antarctica by Cavalcante, Antônio Luthierre Gama, Chaves, Anderson Valério, Fechine, Pierre Basílio Almeida, Holanda Alexandre, Jeferson Yves Nunes, Freire, Tiago Melo, Davi, Dalila Maria Barbosa, Neto, Francisco Simão, de Sousa, Isamayra Germano, da Silva Moreira, Katerine, de Oliveira, André Luiz Barros, de Mattos, Marcos Carlos, Oliveira, Maria Conceição Ferreira, de Brito, Maria Vieira, Ballereau, Stéphanie, Bernardes-Génisson, Vania, da Fonseca, Aluísio Marques, dos Santos, José C.S.

“…Kaolin is a mineral composed of hydrated aluminum silicates, clayey and with high bioavailability. The choice of this mineral as immobilization matrix took…”
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Recent Advances in Lipase-Mediated Preparation of Pharmaceuticals and Their Intermediates by Carvalho, Ana Caroline Lustosa de Melo, Fonseca, Thiago de Sousa, de Mattos, Marcos Carlos, de Oliveira, Maria da Conceição Ferreira, de Lemos, Telma Leda Gomes, Molinari, Francesco, Romano, Diego, Serra, Immacolata

“…Biocatalysis offers an alternative approach to conventional chemical processes for the production of single-isomer chiral drugs. Lipases are one of the most…”
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SDR enzymes oxidize specific lipidic alkynylcarbinols into cytotoxic protein-reactive species by Demange, Pascal, Joly, Etienne, Marcoux, Julien, Zanon, Patrick R A, Listunov, Dymytrii, Rullière, Pauline, Barthes, Cécile, Noirot, Céline, Izquierdo, Jean-Baptiste, Rozié, Alexandrine, Pradines, Karen, Hee, Romain, de Brito, Maria Vieira, Marcellin, Marlène, Serre, Remy-Felix, Bouchez, Olivier, Burlet-Schiltz, Odile, Oliveira, Maria Conceição Ferreira, Ballereau, Stéphanie, Bernardes-Génisson, Vania, Maraval, Valérie, Calsou, Patrick, Hacker, Stephan M, Génisson, Yves, Chauvin, Remi, Britton, Sébastien

“…Hundreds of cytotoxic natural or synthetic lipidic compounds contain chiral alkynylcarbinol motifs, but the mechanism of action of those potential therapeutic…”
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Immobilization of Amano lipase AK from Pseudomonas fluorescens on different types of chitosan-containing supports: use in the kinetic resolution of rac-indanol by de Sousa Fonseca, Thiago, de Oliveira, Ulisses Marcondes Freire, de Oliveira, Maria da Conceição Ferreira, de Lemos, Telma Leda Gomes, da Silva, Marcos Reinaldo, Rios, Nathalia Saraiva, Gonçalves, Luciana Rocha Barros, de Mattos, Marcos Carlos

“…Amano lipase AK from P. fluorescens was immobilized on different types of chitosan-containing supports. Chitosan lower molecular weight (2.5%), chitosan lower…”
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Recent progress in the chemistry of the Stemona alkaloids by Pilli, R A, Ferreira de Oliveira, M C

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Stereogame: An Interactive Computer Game That Engages Students in Reviewing Stereochemistry Concepts by da Silva Júnior, José Nunes, Sousa Lima, Mary Anne, Xerez Moreira, João Victor, Oliveira Alexandre, Francisco Serra, de Almeida, Diego Macedo, de Oliveira, Maria da Conceição Ferreira, Melo Leite Junior, Antonio José

“…This report provides information about an interactive computer game that allows undergraduate students to review individually stereochemistry topics in an…”
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Whole cells of recombinant CYP153A6-E. coli as biocatalyst for regioselective hydroxylation of monoterpenes by Cannazza, Pietro, Rabuffetti, Marco, Donzella, Silvia, De Vitis, Valerio, Contente, Martina L., de Oliveira, Maria da Conceição Ferreira, de Mattos, Marcos C., Barbosa, Francisco G., de Souza Oliveira, Ricardo Pinheiro, Pinto, Andrea, Molinari, Francesco, Romano, Diego

“…Optimized recombinant whole cells of E. coli bearing CYP153A6 were employed for catalyzing the hydroxylation of different monoterpene derivatives. In most…”
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Esterases as stereoselective biocatalysts by Romano, Diego, Bonomi, Francesco, de Mattos, Marcos Carlos, de Sousa Fonseca, Thiago, de Oliveira, Maria da Conceição Ferreira, Molinari, Francesco

“…Non-lypolitic esterases are carboxylester hydrolases with preference for the hydrolysis of water-soluble esters bearing short-chain acyl residues. The…”
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The chemistry of Stemona alkaloids: An update by Pilli, Ronaldo Aloise, Rosso, Giovanni Bernardi, de Oliveira, Maria da Conceição Ferreira

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Chemoenzymatic synthesis of rasagiline mesylate using lipases by Fonseca, Thiago de Sousa, Silva, Marcos Reinaldo da, de Oliveira, Maria da Conceição Ferreira, Lemos, Telma Leda Gomes de, Marques, Ricardo de Araújo, de Mattos, Marcos Carlos

“…•A straightforward chemoenzymatic synthesis of rasagiline mesylate has been developed.•The key steps involved kinetic lipase-mediated resolution and Mitsunobu…”
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Quantification of Barbatusin and 3β-Hydroxy-3-deoxybarbatusin in Plectranthus Species by HPLC-DAD by Mattos, Marcos Carlos de, Oliveira, Maria da Conceição Ferreira de, Lima, Leandro Bezerra, Silva, Maria Goretti de Vasconcelos, Mafezoli, Jair

“…The concentration of diterpenes barbatusin (1) and 3β-hydroxy-3-deoxybarbatusin (2) in the extracts from leaves of Plectranthus grandis, P. barbatus, P…”
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Asymmetric chemoenzymatic synthesis of N-acetyl-α-amino esters based on lipase-catalyzed kinetic resolutions through interesterification reactions by da Silva, Marcos Reinaldo, de Mattos, Marcos Carlos, de Oliveira, Maria da Conceição Ferreira, de Lemos, Telma Leda Gomes, Ricardo, Nágila Maria Pontes Silva, de Gonzalo, Gonzalo, Lavandera, Iván, Gotor-Fernández, Vicente, Gotor, Vicente

“…Several phenylalanine analogs have been synthesized through a four-step route starting from easily available ethyl acetamidocyanoacetate. In a first reaction,…”
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Synthesis and Antifungal Activity In Vitro of Isoniazid Derivatives against Histoplasma capsulatum var. capsulatum by DE AGULAR CORDEIRO, Rossana, DE FARIAS MARQUES, Francisca Jakelyne, PINHEIRO GOMES BANDEIRA, Tereza de Jesus, COSTA SIDRIM, José Júlio, DE AGUIAR CORDEIRO, Rebecca, DA SILVA, Marcos Reinaldo, MAIA MALAQUIAS, Angela Donato, SILVA DE MELO, Charlline Vládia, MAFEZOLI, Jair, FERREIRA DE OLIVEIRA, Maria da Conceição, NOGUEIRA BRILHANTE, Raimunda Sâmia, GADELHA ROCHA, Marcos Fábio

“…Histoplasmosis is a severe infection that affects millions of patients worldwide and is endemic in the Americas. Amphotericin B (AMB) and itraconazole are…”
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Chemoenzymatic synthesis of (S)-Pindolol using lipases by Lima, Gledson Vieira, da Silva, Marcos Reinaldo, de Sousa Fonseca, Thiago, de Lima, Leandro Bezerra, de Oliveira, Maria da Conceição Ferreira, de Lemos, Telma Leda Gomes, Zampieri, Davila, dos Santos, Jose Cleiton Sousa, Rios, Nathalia Saraiva, Gonçalves, Luciana Rocha Barros, Molinari, Francesco, de Mattos, Marcos Carlos

“…[Display omitted] •A straightforward chemoenzymatic synthesis of (S)-Pindolol has been developed.•The key step involved kinetic lipase-mediated resolution of a…”
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Chemoenzymatic synthesis of both enantiomers of propafenone hydrochloride through lipase-catalyzed process by Bezerra, Francisco de Aquino, Lima, Gabriella de Castro, Carvalho, Ana Caroline Lustosa de Melo, Vega, Kimberly Benedetti, Oliveira, Maria Conceição Ferreira, de Lemos, Telma Leda Gomes, Sousa dos Santos, Jose Cleiton, Gonçalves, Luciana Rocha Barros, Rios, Nathalia Saraiva, Fernandez-Lafuente, Roberto, Molinari, Francesco, Zanatta, Geancarlo, de Mattos, Marcos Carlos

“…•A straightforward chemoenzymatic syntheses of propafenone hydrochloride enantiomers has been developed.•The key step involved obtaining both (R)- and (S)-…”
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Improving the kinetic resolution of rac-2-(diphenylthiophosphinoferrocene) methanol catalyzed by Thermomyces lanuginosus lipase immobilized on immobead-150 by Fróes, Naara Oliveira Santana, Bandyopadhyay, Uchchhal, Negreiro, Jonatas Martins, Fonseca, Thiago de Sousa, Nunes, Fátima Miranda, de Mattos, Marcos Carlos, Zanatta, Geancarlo, Pereira, João Victor de Melo, Guimarães, Celina de Jesus, Pessoa, Claudia do Ó, Silva, Bruno Poti e, Manoury, Eric, Oliveira, Maria Conceição Ferreira

“…•Rac-2-(diphenylthiophosphinoferrocene)methanol was resolved by TLL via acylation.•(Rp)-Alcohol (ees >99%) and (Sp)-acetate (eep 98%) were produced (c 50%, E >…”
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Quantification of Barbatusin and 3[beta]-Hydroxy-3-deoxybarbatusin in Plectranthus Species by HPLC-DAD by de Vasconcelos Silva, Maria Goretti, Lima, Leandro Bezerra, de Oliveira, Maria da Conceicao Ferreira, de Mattos, Marcos Carlos, Mafezoli, Jair

“…The concentration of diterpenes barbatusin (1) and 3[beta]-hydroxy-3-deoxybarbatusin (2) in the extracts from leaves of Plectranthus grandis, P. barbatus, P…”
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