Search Results - "Ferreira, Vera F. C."
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In Vivo Pretargeting Based on Cysteine-Selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry
Published in Bioconjugate chemistry (20-01-2021)“…Pretargeted imaging has emerged as an effective multistep strategy aiming to improve imaging contrast and reduce patient radiation exposure through decoupling…”
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Bioconjugate Supramolecular Pd2+ Metallacages Penetrate the Blood Brain Barrier In Vitro and In Vivo
Published in Bioconjugate chemistry (21-07-2021)“…The biomedical application of discrete supramolecular metal-based structures, specifically self-assembled metallacages, is still an emergent field of study…”
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Functionalization of Ruthenium(II) Terpyridine Complexes with Cyclic RGD Peptides To Target Integrin Receptors in Cancer Cells
Published in European journal of inorganic chemistry (27-03-2017)“…The lack of selectivity for cancer cells and the resulting negative impact on healthy tissue is a severe drawback of actual cancer chemotherapy. Tethering of…”
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Improved Fmoc‐solid‐phase peptide synthesis of an extracellular loop of CFTR for antibody selection by the phage display technology
Published in Journal of peptide science (01-07-2020)“…Cystic fibrosis (CF), a life‐shortening genetic disease, is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that codes for the…”
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Nonconventional trans‐Platinum Complexes Functionalized with RDG Peptides: Chemical and Cytototoxicity Studies
Published in European journal of inorganic chemistry (27-03-2017)“…In order for platinum complexes to target cancer cells, trans‐PtII or trans‐PtIV complexes were bioconjugated to the cyclic peptide cRGDfK (cRGD), which has an…”
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Bioconjugate Supramolecular Pd 2+ Metallacages Penetrate the Blood Brain Barrier In Vitro and In Vivo
Published in Bioconjugate chemistry (21-07-2021)“…The biomedical application of discrete supramolecular metal-based structures, specifically self-assembled metallacages, is still an emergent field of study…”
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Technetium-99m complexes of l-arginine derivatives for targeting amino acid transporters
Published in Dalton transactions : an international journal of inorganic chemistry (31-10-2017)“…Although relevant from the clinical point of view, radiotracers targeting cationic amino acid transporters are relatively unexplored and, in particular, no…”
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Targeting of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein with a Technetium‐99m Imaging Probe
Published in ChemMedChem (18-07-2018)“…Cystic fibrosis (CF) is caused by mutations in the gene that encodes the CF transmembrane conductance regulator (CFTR) protein. The most common mutation,…”
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Isostructural Re(I)/(99m)Tc(I) tricarbonyl complexes for cancer theranostics
Published in Organic & biomolecular chemistry (14-05-2015)“…Merging classical organic anticancer drugs with metal-based compounds in one single molecule offers the possibility of exploring new approaches for cancer…”
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