Search Results - "Ferreira, Paulo Michel Pinheiro"

Casearin X, Its Degradation Product and Other Clerodane Diterpenes from Leaves of Casearia sylvestris: Evaluation of Cytotoxicity against Normal and Tumor Human Cells by Gonzaga dos Santos, André, Pinheiro Ferreira, Paulo Michel, Magela Vieira Júnior, Gerardo, Perez, Carla Cristina, Gomes Tininis, Aristeu, Silva, Geraldo Humberto, da Silva Bolzani, Vanderlan, Veras Costa-Lotufo, Letícia, do Ó Pessoa, Cláudia, Cavalheiro, Alberto José

“…An EtOH extract of the leaves of Casearia sylvestris afforded new clerodane diterpene, casearin X, together with the known compounds casearins B, D, L, and O,…”
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Action of aqueous extracts of Phyllanthus niruri L. (Euphorbiaceae) leaves on meristematic root cells of Allium cepa L by Neves, Erasmovlane S B, Ferreira, Paulo Michel Pinheiro, Lima, Leonardo H G M, Peron, Ana Paula

“…This study aimed to evaluate the effects of aqueous extracts of dried Phyllanthus niruri L. (stonebreaker) leaves on Allium cepa L. root meristem cells at four…”
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Toxicological, chemopreventive, and cytotoxic potentialities of rare vegetal species and supporting findings for the Brazilian Unified Health System (SUS) by Silva, Jurandy do Nascimento, Monção, Nayana Bruna Nery, de Farias, Ruth Raquel Soares, Citó, Antonia Maria das Graças Lopes, Chaves, Mariana Helena, Araújo, Mônica Regina Silva de, Lima, Daisy Jereissati Barbosa, Pessoa, Claudia, Lima, Alessandro de, Araújo, Edigênia Cavalcante da Cruz, Militão, Gardenia Carmen Gadelha, Costa, Marcília Pinheiro da, Capasso, Raffaele, Ferreira, Paulo Michel Pinheiro

“…Caatinga flora which are found in a poor Brazilian region contain a substantial number of endemic taxa with biomedical and social importance for regional…”
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Molecular biology of human epidermal receptors, signaling pathways and targeted therapy against cancers: new evidences and old challenges by Ferreira, Paulo Michel Pinheiro, Pessoa, Cláudia

“…Human epidermal receptors (HER1/2/3/4) belong to the class of receptor-type tyrosine kinases. After binding a ligand, dimerization, it will ocurr activation of…”
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Phytol as an anticarcinogenic and antitumoral agent: An in vivo study in swiss mice with DMBA‐Induced breast cancer by de Alencar, Marcus Vinícius Oliveira Barros, Islam, Muhammad Torequl, de Lima, Rosália Maria Torres, Paz, Márcia Fernanda Correia Jardim, Reis, Antonielly Campinho, Mata, Ana Maria Oliveira Ferreira, Filho, José Williams Gomes de Oliveira, Cerqueira, Gilberto Santos, Ferreira, Paulo Michel Pinheiro, e Sousa, João Marcelo de Castro, Mubarak, Mohammad S., Melo‐Cavalcante, Ana Amélia de Carvalho

“…Phytol (PHY) (3,7,11,15‐tetramethylhexadec‐2‐en‐1‐ol) exhibits various pharmacological properties including toxicity and cytotoxicity, and exerts antitumor…”
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Mycotoxin‐assisted mitochondrial dysfunction and cytotoxicity: Unexploited tools against proliferative disorders by Islam, Muhammad Torequl, Mishra, Siddhartha Kumar, Tripathi, Swati, Alencar, Marcus Vinícius Oliveira Barros, e Sousa, João Marcelo de Castro, Rolim, Hercília Maria Lins, de Medeiros, Maria das Graças Freire, Ferreira, Paulo Michel Pinheiro, Rouf, Razina, Uddin, Shaikh Jamal, Mubarak, Mohammad Suleiman, Melo‐Cavalcante, Ana Amélia de Carvalho

“…Mitochondria are the powerhouse of cells, which upon dysfunctions may lead to several diseases. Mycotoxins are the toxic secondary metabolites from fungi which…”
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Retinol palmitate and ascorbic acid: Role in oncological prevention and therapy by de Carvalho Melo-Cavalcante, Ana Amélia, da Rocha Sousa, Leonardo, Alencar, Marcus Vinícius Oliveira Barros, de Oliveira Santos, José Victor, da Mata, Ana Maria oliveira, Paz, Márcia Fernanda Correia Jardim, de Carvalho, Ricardo Melo, Nunes, Nárcia Mariana Fonseca, Islam, Muhammad Torequl, Mendes, Anderson Nogueira, Gonçalves, Juan Carlos Ramos, da Silva, Felipe Cavalcanti Carneiro, Ferreira, Paulo Michel Pinheiro, de Castro e Sousaa, João Marcelo

“…Cancer development has been directly related to oxidative stress. During chemotherapy, some cancer patients use dietary antioxidants to avoid nutritional…”
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Improving Riparin-A Dissolution through a Laponite Based Nanohybrid by Gomes, Duanne Mendes, Meirelles, Lyghia Maria Araújo, Araujo, Paulo Monteiro, de Sousa, Rayran Walter Ramos, Ferreira, Paulo Michel Pinheiro, Gutierrez, Stanley Juan Chavez, de Medeiros, Maria das Graças Freire, Raffin, Fernanda Nervo

“…(1) Background: Riparin-A presents several pharmacological activities already elucidated, such as antimicrobial modulator, antileishmania, anxiolytic,…”
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Physio-pharmacological Investigations About the Anti-inflammatory and Antinociceptive Efficacy of (+)-Limonene Epoxide by de Almeida, Antonia Amanda Cardoso, Silva, Renan Oliveira, Nicolau, Lucas Antonio Duarte, de Brito, Tarcísio Vieira, de Sousa, Damião Pergentino, Barbosa, André Luiz dos Reis, de Freitas, Rivelilson Mendes, Lopes, Luciano da Silva, Medeiros, Jand-Venes Rolim, Ferreira, Paulo Michel Pinheiro

“…ABSTRACT D-limonene epoxidation generates (+)-limonene epoxide, an understudied compound in the pharmacologically point of view. Herein, we investigated the…”
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Antibacterial, Antioxidant, and Anticholinesterase Activities of Plant Seed Extracts from Brazilian Semiarid Region by Carvalho, Ana Fontenele Urano, Melo, Vânia Maria Maciel, Ricardo, Nágila M. P. S., Vasconcelos, Ilka Maria, Cunha, Arcelina Pacheco, Soares, Bruno Marques, Viana, Martônio Ponte, Souza, Terezinha Maria, Farias, Davi Felipe, Ferreira, Paulo Michel Pinheiro

“…The antimicrobial, antioxidant, and anticholinesterase activities of ethanolic seed extracts of twenty-one plant species from Brazilian semiarid region were…”
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In Vitro and Ex Vivo Chemopreventive Action of Mauritia flexuosa Products by Nunes, Nárcia Mariana Fonseca, Lopes, Luciano da Silva, Rolim, Larissa Araújo, Costa-Júnior, Joaquim Soares da, Ferreira, Paulo Michel Pinheiro, de Oliveira, Guilherme Antônio Lopes, Teixeira, Sabrina Almondes, Lima, Ana Cristina Silva de, Arcanjo-Medeiros, Stella Regina, Ramos, Carla Lorena Silva, Lima, Layana Karine F., Oliveira, George L. S., Pereira-Freire, Joilane Alves, Amorim, Vivianne Rodrigues

“…Mauritia flexuosa (Arecaceae), known as “Buriti,” is a Brazilian palm tree with high economic potential for local communities. Herein, we investigated the…”
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Assessing chemical constituents of Mimosa caesalpiniifolia stem bark: possible bioactive components accountable for the cytotoxic effect of M. caesalpiniifolia on human tumour cell lines by Monção, Nayana Bruna Nery, Araújo, Bruno Quirino, Silva, Jurandy do Nascimento, Lima, Daisy Jereissati Barbosa, Ferreira, Paulo Michel Pinheiro, Airoldi, Flavia Pereira da Silva, Pessoa, Cláudia, Citó, Antonia Maria das Graças Lopes

“…Mimosa caesalpiniifolia is a native plant of the Brazilian northeast, and few studies have investigated its chemical composition and biological significance…”
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Moringa oleifera: bioactive compounds and nutritional potential by Ferreira, Paulo Michel Pinheiro(Universidade Federal do Ceará Faculdade de Medicina Departamento de Fisiologia e Farmacologia), Farias, Davi Felipe(Universidade Federal do Ceará Departamento de Bioquímica e Biologia Molecular), Oliveira, José Tadeu de Abreu(Universidade Federal do Ceará Departamento de Bioquímica e Biologia Molecular), Carvalho, Ana de Fátima Urano(Universidade Federal do Ceará Departamento de Biologia)

“…This work aims to review the nutritional properties of the Moringa oleifera tree, emphasizing its main constituents and nutritional applications for humans and…”
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PHENOLIC DERIVATIVES AND ANTIOXIDANT ACTIVITY OF POLAR EXTRACTS FROM Bauhinia pulchella by Carvalho, Adonias, Santos, Lucivania, Farias, Ruth, Chaves, Mariana, Feitosa, Chistiane, Vieira Júnior, Gerardo, Araújo, Mônica, Ferreira, Paulo, Pessoa, Claudia

“…A tea made with the leaves or stem bark of Bauhinia pulchella Benth (Fabaceae) is used in the treatment of diabetes. Ethanol (EEF) and aqueous (EAF) extracts…”
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Assessment of Grape, Plum and Orange Synthetic Food Flavourings Using in vivo Acute Toxicity Tests by Sales, Ila Monize Sousa, Barbosa, Janaína Sousa, Silva Dos Santos, Fabelina Karollyne, Carneiro da Silva, Felipe Cavalcanti, Ferreira, Paulo Michel Pinheiro, Marcelo de Castro E Sousa, João, Peron, Ana Paula

“…The present study evaluates the acute toxicity of synthetic grape, plum and orange flavourings in root meristem cells of at the doses of 3.5, 7.0 and 14.0…”
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Chloroquine and hydroxychloroquine in antitumor therapies based on autophagy-related mechanisms by Ferreira, Paulo Michel Pinheiro, Sousa, Rayran Walter Ramos de, Ferreira, José Roberto de Oliveira, Militão, Gardenia Carmen Gadelha, Bezerra, Daniel Pereira

“…Chloroquine (CQ) and hydroxychloroquine (HCQ) are the most common drugs used to relieve acute and chronic inflammatory diseases. In this article, we present a…”
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Drug development, Brazilian biodiversity and political choices: Where are we heading? by Ferreira, Paulo Michel Pinheiro, Arcanjo, Daniel Dias Rufino, Peron, Ana Paula

“…The aim of this review was to (i) acknowledge structural advantages of natural products (NPs) for designing therapeutic drugs; (ii) emphasize how wildlife…”
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Antiproliferative activity of pristimerin isolated from Maytenus ilicifolia (Celastraceae) in human HL-60 cells by Costa, Patricia Marçal da, Ferreira, Paulo Michel Pinheiro, Bolzani, Vanderlan da Silva, Furlan, Maysa, de Freitas Formenton Macedo dos Santos, Vânia Aparecida, Corsino, Joaquim, de Moraes, Manoel Odorico, Costa-Lotufo, Letícia Veras, Montenegro, Raquel Carvalho, Pessoa, Cláudia

“…Pristimerin has been shown to be cytotoxic to several cancer cell lines. In the present work, the cytotoxicity of pristimerin was evaluated in human tumor cell…”
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Cytotoxic and toxicological effects of phthalimide derivatives on tumor and normal murine cells by Ferreira, Paulo Michel Pinheiro, Da Costa, Patricia Marçal, Costa, Arinice de Menezes, Lima, Daisy Jereissati Barbosa, Drumond, Renata Rosado, Silva, Jurandy do Nascimento, Moreira, Diogo Rodrigo de Magalhães, De Oliveira Filho, Gevânio Bezerra, Ferreira, Jamile Magalhães, De Queiroz, Maria Goretti Rodrigues, Leite, Ana Cristina Lima, Pessoa, Cláudia

“…Eleven phthalimide derivatives were evaluated with regards to their antiproliferative activity on tumor and normal cells and possible toxic effects. Cytotoxic…”
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In vitro antioxidant, antitumor and leishmanicidal activity of riparin A, an analog of the Amazon alkamides from Aniba riparia (Lauraceae) by ARAÚJO, Éverton José Ferreira de, LIMA, Layana Karine Farias, SILVA, Oskar Almeida, JÚNIOR, Luís Mário REZENDE, GUTIERREZ, Stanley Juan Chavez, CARVALHO, Fernando Aécio de Amorim, LIMA, Francisco das Chagas Alves, PESSOA, Cláudia, FREITAS, Rivelilson Mendes de, FERREIRA, Paulo Michel Pinheiro

“…ABSTRACT Aniba riparia (Lauraceae) is an important medicinal plant found in the Amazon region and presents alkaloids of the type alkamide known as riparins…”
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