Search Results - "Ferreira, Paulo C. P."

Activation of the PI3K/Akt Pathway Early during Vaccinia and Cowpox Virus Infections Is Required for both Host Survival and Viral Replication by SOARES, Jamaria A. P, LEITE, Flavia G. G, BONJARDIM, Claudio A, ANDRADE, Luciana G, TORRES, Alice A, DE SOUSA, Lirlandia P, BARCELOS, Luciola S, TEIXEIRA, Mauro M, FERREIRA, Paulo C. P, KROON, Erna G, SOUTO-PADRON, Thais

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One more piece in the VACV ecological puzzle: could peridomestic rodents be the link between wildlife and bovine vaccinia outbreaks in Brazil? by Abrahão, Jônatas S, Guedes, Maria Isabel M, Trindade, Giliane S, Fonseca, Flávio G, Campos, Rafael K, Mota, Bruno F, Lobato, Zélia I P, Silva-Fernandes, André T, Rodrigues, Gisele O L, Lima, Larissa S, Ferreira, Paulo C P, Bonjardim, Cláudio A, Kroon, Erna G

“…Despite the fact that smallpox eradication was declared by the World Health Organization (WHO) in 1980, other poxviruses have emerged and re-emerged, with…”
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MEK/ERK activation plays a decisive role in yellow fever virus replication: Implication as an antiviral therapeutic target by Albarnaz, Jonas D., De Oliveira, Leonardo C., Torres, Alice A., Palhares, Rafael M., Casteluber, Marisa C., Rodrigues, Claudiney M., Cardozo, Pablo L., De Souza, Aryádina M.R., Pacca, Carolina C., Ferreira, Paulo C.P., Kroon, Erna G., Nogueira, Maurício L., Bonjardim, Cláudio A.

“…•Cellular kinases can be employed as therapeutic targets to treat viral infections, by means of small molecule inhibitors.•MEK1/2 inhibitor U0126 impairs the…”
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Acanthamoeba polyphaga mimivirus stability in environmental and clinical substrates: implications for virus detection and isolation by Dornas, Fábio P, Silva, Lorena C F, de Almeida, Gabriel M, Campos, Rafael K, Boratto, Paulo V M, Franco-Luiz, Ana P M, La Scola, Bernard, Ferreira, Paulo C P, Kroon, Erna G, Abrahão, Jônatas S

“…Viruses are extremely diverse and abundant and are present in countless environments. Giant viruses of the Megavirales order have emerged as a fascinating…”
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A Vaccinia Virus-Driven Interplay between the MKK4/7-JNK1/2 Pathway and Cytoskeleton Reorganization by PEREIRA, Anna C. T. C, LEITE, Flávia G. G, BONJARDIM, Cláudio A, BRASIL, Bruno S. A. F, SOARES-MARTINS, Jamaria A. P, TORRES, Alice A, PIMENTA, Paulo F. P, SOUTO-PADRON, Thaïs, TRAKTMAN, Paula, FERREIRA, Paulo C. P, KROON, Erna G

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Adverse events post smallpox-vaccination: insights from tail scarification infection in mice with Vaccinia virus by Mota, Bruno E F, Gallardo-Romero, Nadia, Trindade, Giliane, Keckler, M Shannon, Karem, Kevin, Carroll, Darin, Campos, Marco A, Vieira, Leda Q, da Fonseca, Flávio G, Ferreira, Paulo C P, Bonjardim, Cláudio A, Damon, Inger K, Kroon, Erna G

“…Adverse events upon smallpox vaccination with fully-replicative strains of Vaccinia virus (VACV) comprise an array of clinical manifestations that occur…”
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Dengue virus 3 clinical isolates show different patterns of virulence in experimental mice infection by Ferreira, Gustavo P., Figueiredo, Leandra B., Coelho, Luiz F.L., Junior, Policarpo A.S., Cecilio, Alzira B., Ferreira, Paulo C.P., Bonjardim, Cláudio A., Arantes, Rosa M.E., Campos, Marco A., Kroon, Erna G.

“…Dengue virus (DENV) may cause symptomatic infection with mild, undifferentiated febrile illness called classical dengue fever (DF) or a more severe disease,…”
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The dengue virus nonstructural protein 1 (NS1) increases NF-κB transcriptional activity in HepG2 cells by Silva, Breno M., Sousa, Lirlândia P., Gomes-Ruiz, Alessandra C., Leite, Flávia G. G., Teixeira, Mauro M., da Fonseca, Flávio G., Pimenta, Paulo F. P., Ferreira, Paulo C. P., Kroon, Erna G., Bonjardim, Cláudio A.

“…Dengue virus nonstructural protein 1 (NS1) is a glycoprotein involved in viral RNA replication. NS1 associates with host cell proteins and can be found in…”
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SP600125 inhibits Orthopoxviruses replication in a JNK1/2 -independent manner: Implication as a potential antipoxviral by Pereira, Anna C.T.C., Soares-Martins, Jamária A.P., Leite, Flávia G.G., Da Cruz, André F.P., Torres, Alice A., Souto-Padrón, Thais, Kroon, Erna G., Ferreira, Paulo C.P., Bonjardim, Cláudio A.

“…The pharmacological inhibitor SP600125 [anthra(1,9-cd)pyrazol-6(2H)-one 1,9-pyrazoloanthrone] has been largely employed as a c-JUN N-terminal kinase (JNK1/2)…”
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Mycobacteria mobility shift assay: a method for the rapid identification of Mycobacterium tuberculosis and nontuberculous mycobacteria by Wildner, Letícia Muraro, Bazzo, Maria Luiza, Liedke, Susie Coutinho, Nogueira, Christiane Lourenço, Segat, Gabriela, Senna, Simone Gonçalves, Schlindwein, Aline Daiane, de Oliveira, Jaquelline Germano, Rovaris, Darcita B, Bonjardim, Claudio A, Kroon, Erna G, Ferreira, Paulo C.P

“…The identification of mycobacteria is essential because tuberculosis (TB) and mycobacteriosis are clinically indistinguishable and require different…”
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Detection and phylogenetic analysis of Orf virus from sheep in Brazil: a case report by Abrahão, Jônatas S, Campos, Rafael K, Trindade, Giliane S, Guedes, Maria I M, Lobato, Zélia I P, Mazur, Carlos, Ferreira, Paulo C P, Bonjardim, Cláudio A, Kroon, Erna G

“…Orf virus (ORFV), the prototype of the genus Parapoxvirus (PPV), is the etiological agent of contagious ecthyma, a severe exanthematic dermatitis that afflicts…”
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The interplay between Araçatuba virus and host signaling pathways: role of PI3K/Akt in viral replication by de Freitas, Marcelo H. A., de Oliveira, Leonardo C., Mügge, Fernanda L. B., Ferreira, Paulo C. P., Trindade, Giliane de S., Kroon, Erna G., Bonjardim, Cláudio A.

“…In this study, we describe the interaction between Araçatuba virus (ARAV), a naturally occurring Brazilian vaccinia virus isolated from an outbreak at a dairy…”
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c-Jun integrates signals from both MEK/ERK and MKK/JNK pathways upon vaccinia virus infection by Leite, Flávia G. G., Torres, Alice A., De Oliveira, Leonardo C., Da Cruz, André F. P., Soares-Martins, Jamária A. P., Pereira, Anna C. T. C., Trindade, Giliane S., Abrahão, Jonatas S., Kroon, Erna G., Ferreira, Paulo C. P., Bonjardim, Cláudio A.

“…Usurpation of the host’s signalling pathways is a common strategy employed by viruses to promote their successful replication. Here we show that infection with…”
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Differential role played by the MEK/ERK/EGR-1 pathway in orthopoxviruses vaccinia and cowpox biology by Silva, Patrícia N G, Soares, Jamária A P, Brasil, Bruno S A F, Nogueira, Sarah V, Andrade, Anderson A, de Magalhães, José C, Bonjardim, Marisa B, Ferreira, Paulo C P, Kroon, Erna G, Bruna-Romero, Oscar, Bonjardim, Cláudio A

“…Appropriation of signalling pathways facilitates poxvirus replication. Poxviruses, as do most viruses, try to modify the host cell environment to achieve…”
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Serological Evidence of Orthopoxvirus Circulation Among Equids, Southeast Brazil by Borges, Iara A, Reynolds, Mary G, McCollum, Andrea M, Figueiredo, Poliana O, Ambrosio, Lara L D, Vieira, Flavia N, Costa, Galileu B, Matos, Ana C D, de Andrade Almeida, Valeria M, Ferreira, Paulo C P, Lobato, Zélia I P, Dos Reis, Jenner K P, Kroon, Erna G, Trindade, Giliane S

“…Since 1999 (VACV) outbreaks involving bovines and humans have been reported in Brazil; this zoonosis is known as Bovine Vaccinia (BV) and is mainly an…”
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Short report: Isolation of two vaccinia virus strains from a single bovine vaccinia outbreak in rural area from Brazil: Implications on the emergence of zoonotic orthopoxviruses by Trindade, Giliane S, Lobato, Zélia I P, Drumond, Betânia P, Leite, Juliana A, Trigueiro, Ricardo C, Guedes, Maria I M C, da Fonseca, Flávio G, dos Santos, João R, Bonjardim, Cláudio A, Ferreira, Paulo C P, Kroon, Erna G

“…Outbreaks of bovine vaccinia disease caused by circulation of Vaccinia virus (VACV) strains have been a common occurrence in Brazil in the recent years, being…”
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The vaccinia virus-stimulated mitogen-activated protein kinase (MAPK) pathway is required for virus multiplication by Andrade, Anderson A, Silva, Patrícia N G, Pereira, Anna C T C, De Sousa, Lirlândia P, Ferreira, Paulo C P, Gazzinelli, Ricardo T, Kroon, Erna G, Ropert, Catherine, Bonjardim, Cláudio A

“…Early events play a decisive role in virus multiplication. We have shown previously that activation of MAPK/ERK1/2 (mitogen-activated protein…”
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Recombinant envelope protein (rgp90) ELISA for equine infectious anemia virus provides comparable results to the agar gel immunodiffusion by Reis, Jenner K.P., Diniz, Rejane S., Haddad, João P.A., Ferraz, Isabella B.F., Carvalho, Alex F., Kroon, Erna G., Ferreira, Paulo C.P., Leite, Rômulo C.

“…► A recombinant envelope protein (rgp90) of equine infectious anemia virus was expressed in E. coli. ► The rgp90 was evaluated in an enzyme-linked…”
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Interferons: Signaling, antiviral and viral evasion by Bonjardim, Cláudio A, Ferreira, Paulo C.P, Kroon, Erna G

“…Abstract Interferons (IFNs) were discovered as antiviral agents 50 years ago, and enormous progress has been made since then. Nowadays, IFNs (specifically type…”
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Belo Horizonte virus: a vaccinia-like virus lacking the A-type inclusion body gene isolated from infected mice by Trindade, Giliane S, da Fonseca, Flavio G, Marques, Joao T, Diniz, Sueli, Leite, Juliana A, De Bodt, Stefanie, Van der Peer, Yves, Bonjardim, Claudio A, Ferreira, Paulo C. P, Kroon, Erna G

“…1 Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Avenida Antônio Carlos 6627,…”
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