Search Results - "Ferreira, Paulo A"
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The coming-of-age of nucleocytoplasmic transport in motor neuron disease and neurodegeneration
Published in Cellular and molecular life sciences : CMLS (01-06-2019)“…The nuclear pore is the gatekeeper of nucleocytoplasmic transport and signaling through which a vast flux of information is continuously exchanged between the…”
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Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes
Published in Disease models & mechanisms (01-05-2017)“…The pathogenic drivers of sporadic and familial motor neuron disease (MND), such amyotrophic lateral sclerosis (ALS), are unknown. MND impairs the Ran GTPase…”
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3
Nucleocytoplasmic transport at the crossroads of proteostasis, neurodegeneration and neuroprotection
Published in FEBS letters (01-10-2023)“…Nucleocytoplasmic transport comprises the multistep assembly, transport, and disassembly of protein and RNA cargoes entering and exiting nuclear pores…”
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Sedimentary record of PAHs in the Barigui River and its relation to the socioeconomic development of Curitiba, Brazil
Published in The Science of the total environment (01-06-2014)“…Concentrations of polycyclic aromatic hydrocarbons (PAHs) were determined in a sediment core collected from the Barigui River, in Curitiba, South Brazil. The…”
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Nurse students’ competences in interprofessional pharmaceutical care in Europe: Cross-sectional evaluation
Published in Nurse education in practice (01-11-2022)“…Safe pharmaceutical care requires competent nurses with specific knowledge, skills and attitudes. It is unclear whether nursing students are adequately…”
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Association of the Kinesin-Binding Domain of RanBP2 to KIF5B and KIF5C Determines Mitochondria Localization and Function
Published in Traffic (Copenhagen, Denmark) (01-12-2007)“…The Ran-binding protein 2 (RanBP2) is a large mosaic protein with a pleiotropic role in cell function. Although the contribution of each partner and domain of…”
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7
Estimation of Vertical, Lateral, and Longitudinal Tire Forces in Four-Wheel Vehicles Using a Delayed Interconnected Cascade-Observer Structure
Published in IEEE/ASME transactions on mechatronics (01-04-2019)“…The knowledge of tire-ground interaction forces is valuable for intelligent vehicles technologies. However, tire forces transducers are expensive and not…”
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8
Effects of zinc addition to a copper-contaminated vineyard soil on sorption of Zn by soil and plant physiological responses
Published in Ecotoxicology and environmental safety (01-07-2016)“…The occurrence of high levels of Cu in vineyard soils is often the result of intensive use of fungicides for the preventive control of foliar diseases and can…”
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Assessment of historical fecal contamination in Curitiba, Brazil, in the last 400 years using fecal sterols
Published in The Science of the total environment (15-09-2014)“…A 400-year sedimentary record of the Barigui River was investigated using fecal biomarkers and nutrient distribution. The temporal variability in cholesterol,…”
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10
RPGRIP1 is essential for normal rod photoreceptor outer segment elaboration and morphogenesis
Published in Human molecular genetics (15-11-2009)“…The function of the retinitis pigmentosa GTPase regulator interacting protein 1 (RPGRIP1) gene is currently not known. However, mutations within the gene lead…”
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Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors
Published in PLoS genetics (01-06-2013)“…Non-autonomous cell-death is a cardinal feature of the disintegration of neural networks in neurodegenerative diseases, but the molecular bases of this process…”
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Personal essay of a rookie's journey with Bill Pak and his legacy: tales and perspectives on PI-PLC, NorpA and cyclophilin, NinaA - William L. Pak, PhD., 1932-2023: in memoriam
Published in Journal of neurogenetics (24-06-2024)“…The neurogenetics and vision community recently mourned William L. Pak, PhD, whose pioneering work spearheaded the genetic, electrophysiological, and molecular…”
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RANBP2 is an allosteric activator of the conventional kinesin-1 motor protein, KIF5B, in a minimal cell-free system
Published in EMBO reports (01-05-2009)“…The association of cargoes to kinesins is thought to promote kinesin activation, yet the validation of such a model with native cargoes is lacking because none…”
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Correction to: The coming-of-age of nucleocytoplasmic transport in motor neuron disease and neurodegeneration
Published in Cellular and molecular life sciences : CMLS (01-06-2019)“…The original version of this article unfortunately contained the following misspelling and formatting mistakes…”
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RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism
Published in PLoS genetics (01-10-2006)“…The Ran-binding protein 2 (RanBP2) is a large multimodular and pleiotropic protein. Several molecular partners with distinct functions interacting specifically…”
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Cross-sectional evaluation of pharmaceutical care competences in nurse education: how well do curricula prepare students of different educational levels?
Published in BMC nursing (06-02-2024)“…Nurses play an important role in interprofessional pharmaceutical care. Curricula related to pharmaceutical care, however, vary a lot. Mapping the presence of…”
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Coupling spectroscopic and chromatographic techniques for evaluation of the depositional history of hydrocarbons in a subtropical estuary
Published in Environmental pollution (1987) (01-10-2015)“…Spectroscopic and chromatographic techniques can be used together to evaluate hydrocarbon inputs to coastal environments such as the Paranaguá estuarine system…”
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Interaction of Nephrocystin-4 and RPGRIP1 Is Disrupted by Nephronophthisis or Leber Congenital Amaurosis-Associated Mutations
Published in Proceedings of the National Academy of Sciences - PNAS (20-12-2005)“…RPGR-interacting protein 1 (RPGRIP1) is a key component of cone and rod photoreceptor cells, where it interacts with RPGR (retinitis pigmentosa GTPase…”
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The Cyclophilin-like Domain of Ran-binding Protein-2 Modulates Selectively the Activity of the Ubiquitin-Proteasome System and Protein Biogenesis
Published in The Journal of biological chemistry (30-11-2007)“…The ubiquitin-proteasome system (UPS) plays a critical role in protein degradation. The 19S regulatory particle (RP) of the 26S proteasome mediates the…”
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On the Solution of Generalized Multiplicative Extremum Problems
Published in Journal of optimization theory and applications (01-05-2011)“…The paper addresses the problem of maximizing a sum of products of positive and concave real-valued functions over a convex feasible set. A reformulation based…”
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