Search Results - "Ferreira, Luís M.A."

Crystal Structures of Clostridium thermocellum Xyloglucanase, XGH74A, Reveal the Structural Basis for Xyloglucan Recognition and Degradation by Martinez-Fleites, Carlos, Guerreiro, Catarina I.P.D., Baumann, Martin J., Taylor, Edward J., Prates, José A.M., Ferreira, Luís M.A., Fontes, Carlos M.G.A., Brumer, Harry, Davies, Gideon J.

“…The enzymatic degradation of the plant cell wall is central both to the natural carbon cycle and, increasingly, to environmentally friendly routes to biomass…”
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Cell-surface Attachment of Bacterial Multienzyme Complexes Involves Highly Dynamic Protein-Protein Anchors by Cameron, Kate, Najmudin, Shabir, Alves, Victor D., Bayer, Edward A., Smith, Steven P., Bule, Pedro, Waller, Helen, Ferreira, Luís M.A., Gilbert, Harry J., Fontes, Carlos M.G.A.

“…Protein-protein interactions play a pivotal role in the assembly of the cellulosome, one of nature's most intricate nanomachines dedicated to the…”
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Understanding How Noncatalytic Carbohydrate Binding Modules Can Display Specificity for Xyloglucan by Luís, Ana S., Venditto, Immacolata, Temple, Max J., Rogowski, Artur, Baslé, Arnaud, Xue, Jie, Knox, J. Paul, Prates, José A.M., Ferreira, Luís M.A., Fontes, Carlos M.G.A., Najmudin, Shabir, Gilbert, Harry J.

“…Plant biomass is central to the carbon cycle and to environmentally sustainable industries exemplified by the biofuel sector. Plant cell wall degrading enzymes…”
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Novel Clostridium thermocellum Type I Cohesin-Dockerin Complexes Reveal a Single Binding Mode by Brás, Joana L.A., Alves, Victor D., Carvalho, Ana Luísa, Najmudin, Shabir, Prates, José A.M., Ferreira, Luís M.A., Bolam, David N., Romão, Maria João, Gilbert, Harry J., Fontes, Carlos M.G.A.

“…Protein-protein interactions play a pivotal role in a large number of biological processes exemplified by the assembly of the cellulosome. Integration of…”
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Evidence for a dual binding mode of dockerin modules to cohesins by Carvalho, Ana Luísa, Dias, Fernando M.V, Nagy, Tibor, Prates, José A.M, Proctor, Mark R, Smith, Nicola, Bayer, Edward A, Davies, Gideon J, Ferreira, Luís M.A, Romão, Maria J, Fontes, Carlos M.G.A, Gilbert, Harry J

“…The assembly of proteins that display complementary activities into macromolecular complexes is critical to cellular function. One such enzyme complex, of…”
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Structure and Activity of Two Metal Ion-dependent Acetylxylan Esterases Involved in Plant Cell Wall Degradation Reveals a Close Similarity to Peptidoglycan Deacetylases by Taylor, Edward J., Gloster, Tracey M., Turkenburg, Johan P., Vincent, Florence, Brzozowski, A. Marek, Dupont, Claude, Shareck, François, Centeno, Maria S.J., Prates, José A.M., Puchart, Vladimír, Ferreira, Luís M.A., Fontes, Carlos M.G.A., Biely, Peter, Davies, Gideon J.

“…The enzymatic degradation of plant cell wall xylan requires the concerted action of a diverse enzymatic syndicate. Among these enzymes are xylan esterases,…”
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Galactanases and Mannanases Improve the Nutritive Value of Maize and Soybean Meal Based Diets for Broiler Chicks by Maria S.J. Centeno, Patrícia I.P. Ponte, Teresa Ribeiro, José A.M. Prates, M.A. Luís Ferreira, Manuel C. Soares, Harry J. Gilbert, Carlos M.G.A. Fontes

“…Maize and soybean meal are the most common ingredients in diets for monogastric animals. Although maize is low in anti-nutritive factors, soybean meal often…”
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Family 42 carbohydrate-binding modules display multiple arabinoxylan-binding interfaces presenting different ligand affinities by Ribeiro, Teresa, Santos-Silva, Teresa, Alves, Victor D., Dias, Fernando M.V., Luís, Ana S., Prates, José A.M., Ferreira, Luís M.A., Romão, Maria J., Fontes, Carlos M.G.A

“…Enzymes that degrade plant cell wall polysaccharides display a modular architecture comprising a catalytic domain bound to one or more non-catalytic…”
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Family 6 carbohydrate-binding modules display multiple β1,3-linked glucan-specific binding interfaces by Correia, Márcia A.S, Pires, Virgínia M.R, Gilbert, Harry J, Bolam, David N, Fernandes, Vânia O, Alves, Victor D, Prates, José A.M, Ferreira, Luís M.A, Fontes, Carlos M.G.A

“…Noncatalytic carbohydrate-binding modules (CBMs), which are found in a variety of carbohydrate-degrading enzymes, have been grouped into sequence-based…”
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Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction by Bule, Pedro, Pires, Virgínia M. R., Alves, Victor D., Carvalho, Ana Luísa, Prates, José A. M., Ferreira, Luís M. A., Smith, Steven P., Gilbert, Harry J., Noach, Ilit, Bayer, Edward A., Najmudin, Shabir, Fontes, Carlos M. G. A.

“…Cellulosomes are highly sophisticated molecular nanomachines that participate in the deconstruction of complex polysaccharides, notably cellulose and…”
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The Mechanisms by Which Family 10 Glycoside Hydrolases Bind Decorated Substrates by Pell, Gavin, Taylor, Edward J., Gloster, Tracey M., Turkenburg, Johan P., Fontes, Carlos M.G.A., Ferreira, Luis M.A., Nagy, Tibor, Clark, Samantha J., Davies, Gideon J., Gilbert, Harry J.

“…Endo-β-1,4-xylanases (xylanases), which cleave β-1,4 glycosidic bonds in the xylan backbone, are important components of the repertoire of enzymes that…”
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A dual cohesin–dockerin complex binding mode in Bacteroides cellulosolvens contributes to the size and complexity of its cellulosome by Duarte, Marlene, Viegas, Aldino, Alves, Victor D., Prates, José A.M., Ferreira, Luís M.A., Najmudin, Shabir, Cabrita, Eurico J., Carvalho, Ana Luísa, Fontes, Carlos M.G.A., Bule, Pedro

“…The Cellulosome is an intricate macromolecular protein complex that centralizes the cellulolytic efforts of many anaerobic microorganisms through the promotion…”
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Complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition by Venditto, Immacolata, Luis, Ana S., Rydahl, Maja, Schückel, Julia, Fernandes, Vânia O., Vidal-Melgosa, Silvia, Bule, Pedro, Goyal, Arun, Pires, Virginia M. R., Dourado, Catarina G., Ferreira, Luís M. A., Coutinho, Pedro M., Henrissat, Bernard, Knox, J. Paul, Baslé, Arnaud, Najmudin, Shabir, Gilbert, Harry J., Willats, William G. T., Fontes, Carlos M. G. A.

“…The breakdown of plant cell wall (PCW) glycans is an important biological and industrial process. Noncatalytic carbohydrate binding modules (CBMs) fulfill a…”
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Structure-function studies can improve binding affinity of cohesin-dockerin interactions for multi-protein assemblies by Duarte, Marlene, Alves, Victor D., Correia, Márcia, Caseiro, Catarina, Ferreira, Luís M.A., Romão, Maria João, Carvalho, Ana Luísa, Najmudin, Shabir, Bayer, Edward A., Fontes, Carlos M.G.A., Bule, Pedro

“…The cellulosome is an elaborate multi-enzyme structure secreted by many anaerobic microorganisms for the efficient degradation of lignocellulosic substrates…”
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Family 46 Carbohydrate-binding Modules Contribute to the Enzymatic Hydrolysis of Xyloglucan and β-1,3–1,4-Glucans through Distinct Mechanisms by Venditto, Immacolata, Najmudin, Shabir, Luís, Ana S., Ferreira, Luís M.A., Sakka, Kazuo, Knox, J. Paul, Gilbert, Harry J., Fontes, Carlos M.G.A.

“…Structural carbohydrates comprise an extraordinary source of energy that remains poorly utilized by the biofuel sector as enzymes have restricted access to…”
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Structure–function analyses generate novel specificities to assemble the components of multienzyme bacterial cellulosome complexes by Bule, Pedro, Cameron, Kate, Prates, José A.M., Ferreira, Luís M.A., Smith, Steven P., Gilbert, Harry J., Bayer, Edward A., Najmudin, Shabir, Fontes, Carlos M. G.A., Alves, Victor D.

“…The cellulosome is a remarkably intricate multienzyme nanomachine produced by anaerobic bacteria to degrade plant cell wall polysaccharides. Cellulosome…”
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Single Binding Mode Integration of Hemicellulose-degrading Enzymes via Adaptor Scaffoldins in Ruminococcus flavefaciens Cellulosome by Bule, Pedro, Alves, Victor D., Leitão, André, Ferreira, Luís M.A., Bayer, Edward A., Smith, Steven P., Gilbert, Harry J., Najmudin, Shabir, Fontes, Carlos M.G.A.

“…The assembly of one of Nature's most elaborate multienzyme complexes, the cellulosome, results from the binding of enzyme-borne dockerins to reiterated cohesin…”
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Generation of a library of carbohydrate-active enzymes for plant biomass deconstruction by Cardoso Lopes, Vânia Alexandra da Silva, Bras, Joana L. A., Costa, Ines F., Ferreira, Luis M. A., Gama, Luis, Vincentelli, Renaud, Henrissat, Bernard, Fontes, Carlos

“…Áreas de pesquisa: Biochemistry & Molecular Biology ; Chemistry In nature, the deconstruction of plant carbohydrates is carried out by carbohydrate-active…”
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Stability and Ligand Promiscuity of Type A Carbohydrate-binding Modules Are Illustrated by the Structure of Spirochaeta thermophila StCBM64C by Pires, Virgínia M.R., Pereira, Pedro M.M., Brás, Joana L.A., Correia, Márcia, Cardoso, Vânia, Bule, Pedro, Alves, Victor D., Najmudin, Shabir, Venditto, Immacolata, Ferreira, Luís M.A., Romão, Maria João, Carvalho, Ana Luísa, Fontes, Carlos M.G.A., Prazeres, Duarte Miguel

“…Deconstruction of cellulose, the most abundant plant cell wall polysaccharide, requires the cooperative activity of a large repertoire of microbial enzymes…”
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The Structure of the Feruloyl Esterase Module of Xylanase 10B from Clostridium thermocellum Provides Insights into Substrate Recognition by Prates, José A.M., Tarbouriech, Nicolas, Charnock, Simon J., Fontes, Carlos M.G.A., Ferreira, Luı́s M.A., Davies, Gideon J.

“…Background: Degradation of the plant cell wall requires the synergistic action of a consortium of predominantly modular enzymes. In Clostridiae, these…”
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