Search Results - "Ferreira, Luís Carlos Souza"

Bacillus subtilis spores as vaccine adjuvants: further insights into the mechanisms of action by de Souza, Renata Damásio, Batista, Milene Tavares, Luiz, Wilson Barros, Cavalcante, Rafael Ciro Marques, Amorim, Jaime Henrique, Bizerra, Raíza Sales Pereira, Martins, Eduardo Gimenes, Ferreira, Luís Carlos de Souza

“…Bacillus subtilis spores have received growing attention regarding potential biotechnological applications, including the use as probiotics and in vaccine…”
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Streptococcus mutans glutamate binding protein (GlnH) as antigen target for a mucosal anti-caries vaccine by de Souza Pereira, Gisela, Batista, Milene Tavares, dos Santos, Nayara Fernanda Barros, Passos, Hélic Moreira, da Silva, Dalva Adelina, Ferreira, Ewerton Lucena, de Souza Ferreira, Luís Carlos, de Cássia Café Ferreira, Rita

“…Background In recent years, several studies have demonstrated that bacterial ABC transporters present relevant antigen targets for the development of vaccines…”
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Strain-specific transcriptional and posttranscriptional regulation of heat-labile toxin expression by enterotoxigenic Escherichia coli by Rodrigues, Juliana Falcão, Lourenço, Rogério Ferreira, Maeda, Denicar Lina Nascimento Fabris, de Jesus Cintra, Mariana, Nakao, Naomi, Mathias-Santos, Camila, Luiz, Wilson Barros, de Souza Ferreira, Luís Carlos

“…Enterotoxigenic Escherichia coli (ETEC) represents one of the most important etiological agents of diarrhea in developing countries and characteristically…”
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Association of high pressure and alkaline condition for solubilization of inclusion bodies and refolding of the NS1 protein from zika virus by Rosa da Silva, Cleide Mara, Chura-Chambi, Rosa Maria, Ramos Pereira, Lennon, Cordeiro, Yraima, de Souza Ferreira, Luís Carlos, Morganti, Ligia

“…Proteins in inclusion bodies (IBs) present native-like secondary structures. However, chaotropic agents at denaturing concentrations, which are widely used for…”
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Modulating APOBEC expression enhances DNA vaccine immunogenicity by Almeida, Rafael Ribeiro, Raposo, Rui André Saraiva, Coirada, Fernanda Caroline, Silva, Jamile Ramos, Souza Ferreira, Luís Carlos, Kalil, Jorge, Nixon, Douglas F, Cunha‐Neto, Edecio

“…DNA vaccines have failed to induce satisfactory immune responses in humans. Several mechanisms of double‐stranded DNA (dsDNA) sensing have been described, and…”
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NS1-based ELISA test efficiently detects dengue infections without cross-reactivity with Zika virus by Pereira, Samuel Santos, Andreata-Santos, Robert, Pereira, Lennon Ramos, Soares, Camila Pereira, Félix, Alvina Clara, de Andrade, Patrícia de Mello Jungmann Cardoso, Durigon, Edison Luís, Romano, Camila Malta, Ferreira, Luís Carlos de Souza

“…•Dengue virus (DENV) recombinant ΔNS1 proteins preserve immune dominant B-cell epitopes.•ΔNS1 shows reduced cross-reactivity with anti-Zika virus (ZIKV)…”
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Immunization with a recombinant BibA surface protein confers immunity and protects mice against group B Streptococcus (GBS) vaginal colonization by dos Santos, Nayara Fernanda Barros, da Silva, Lukas Raposo, Costa, Fagner James Martins Dantas, de Mattos, Daniely Maranhão, de Carvalho, Enéas, Ferreira, Luís Carlos de Souza, Ferreira, Rita de Cássia Café

“…•Recombinant GBS-V BibA induced local and systemic immune responses in immunized mice.•BibA-specific antibodies reduced GBS-V invasion and increased the…”
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Specificity of NS1-based immunochromatographic tests for dengue virus with regard to the Zika virus protein by Andreata-Santos, Robert, Pereira, Samuel Santos, Pereira, Lennon Ramos, Félix, Alvina Clara, Romano, Camila Malta, Ferreira, Luís Carlos de Souza

“…This study was performed to determine whether Dengue virus (DENV) immunochromatographic tests can detect and differentiate nonstructural protein 1 (NS1) from…”
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Adverse events of vaccines and the consequences of non-vaccination: a critical review by Aps, Luana Raposo de Melo Moraes, Piantola, Marco Aurélio Floriano, Pereira, Sara Araujo, Castro, Julia Tavares de, Santos, Fernanda Ayane de Oliveira, Ferreira, Luís Carlos de Souza

“…To analyze the risks related to vaccines and the impacts of non-vaccination on the world population. This is a narrative review that has considered information…”
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A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice by Freyn, Alec W., Ramos da Silva, Jamile, Rosado, Victoria C., Bliss, Carly M., Pine, Matthew, Mui, Barbara L., Tam, Ying K., Madden, Thomas D., de Souza Ferreira, Luís Carlos, Weissman, Drew, Krammer, Florian, Coughlan, Lynda, Palese, Peter, Pardi, Norbert, Nachbagauer, Raffael

“…Influenza viruses are respiratory pathogens of public health concern worldwide with up to 650,000 deaths occurring each year. Seasonal influenza virus vaccines…”
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LT adjuvant modulates epitope specificity and improves the efficacy of murine antibodies elicited by sublingual vaccination with the N-terminal domain of Streptococcus mutans P1 by Batista, Milene Tavares, Ferreira, Ewerton Lucena, Pereira, Gisela de Souza, Stafford, Phillip, Maeda, Denicar Lina Nascimento Fabris, Rodrigues, Juliana Falcão, Brady, L. Jeannine, Johnston, Stephen Albert, Ferreira, Luís Carlos de Souza, Ferreira, Rita de Cássia Café

“…In this study, we evaluated the immunogenicity, protective efficacy and peptide-based immune signatures of antibodies raised in mice after sublingual…”
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Layer-by-Layer Assembly of Polymeric Nanoparticles with Heparin-RBD Complexes as an Adjuvant for SARS-CoV‑2 Protein-Based Vaccines by Delechiave, Giovanne, de Oliveira Silva, Mariangela, de Castro-Amarante, Maria Fernanda, Mallaupoma Camarena, Denisse Esther, Venceslau-Carvalho, Alexia A., Ferreira, Luís Carlos de Souza, Catalani, Luiz Henrique

“…Multilayered polymeric particles work as carriers of compounds with controlled release triggered by the layer’s disassembly, allowing chemical stability along…”
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Optimization and scale-up production of Zika virus ΔNS1 in Escherichia coli: application of Response Surface Methodology by Kanno, Alex Issamu, Leite, Luciana Cezar de Cerqueira, Pereira, Lennon Ramos, de Jesus, Mônica Josiane Rodrigues, Andreata-Santos, Robert, Alves, Rúbens Prince dos Santos, Durigon, Edison Luiz, Ferreira, Luís Carlos de Souza, Gonçalves, Viviane Maimoni

“…Diagnosing Zika virus (ZIKV) infections has been challenging due to the cross-reactivity of induced antibodies with other flavivirus. The concomitant…”
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CpG Oligodeoxinucleotides and Flagellin Modulate the Immune Response to Antigens Targeted to CD8α + and CD8α - Conventional Dendritic Cell Subsets by Antonialli, Renan, Sulczewski, Fernando Bandeira, Amorim, Kelly Nazaré da Silva, Almeida, Bianca da Silva, Ferreira, Natália Soares, Yamamoto, Márcio Massao, Soares, Irene Silva, Ferreira, Luís Carlos de Souza, Rosa, Daniela Santoro, Boscardin, Silvia Beatriz

“…Dendritic cells (DCs) are antigen-presenting cells essential for the induction of adaptive immune responses. Their unprecedented ability to present antigens to…”
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A genetic and pathologic study of a DENV2 clinical isolate capable of inducing encephalitis and hematological disturbances in immunocompetent mice by Amorim, Jaime Henrique, Pereira Bizerra, Raíza Sales, dos Santos Alves, Rúbens Prince, Sbrogio-Almeida, Maria Elisabete, Levi, José Eduardo, Capurro, Margareth Lara, de Souza Ferreira, Luís Carlos

“…Dengue virus (DENV) is the causative agent of dengue fever (DF), a mosquito-borne illness endemic to tropical and subtropical regions. There is currently no…”
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The Anti-Dengue Virus Peptide DV2 Inhibits Zika Virus Both In Vitro and In Vivo by Castro-Amarante, Maria Fernanda de, Pereira, Samuel Santos, Pereira, Lennon Ramos, Santos, Lucas Souza, Venceslau-Carvalho, Alexia Adrianne, Martins, Eduardo Gimenes, Balan, Andrea, Souza Ferreira, Luís Carlos de

“…The C-terminal portion of the E protein, known as stem, is conserved among flaviviruses and is an important target to peptide-based antiviral strategies. Since…”
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Design, Immune Responses and Anti-Tumor Potential of an HPV16 E6E7 Multi-Epitope Vaccine by de Oliveira, Liliane Maria Fernandes, Morale, Mirian Galliote, Chaves, Agatha A Muniz, Cavalher, Aline Marques, Lopes, Aline Soriano, Diniz, Mariana de Oliveira, Schanoski, Alessandra Soares, de Melo, Robson Lopes, Ferreira, Luís Carlos de Souza, de Oliveira, Maria Leonor S, Demasi, Marilene, Ho, Paulo Lee

“…Cervical cancer is a common type of cancer among women worldwide and infection with high-risk human papillomavirus (HPVs) types represents the major risk…”
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Production of a Recombinant Dengue Virus 2 NS5 Protein and Potential Use as a Vaccine Antigen by Alves, Rúbens Prince Dos Santos, Pereira, Lennon Ramos, Fabris, Denicar Lina Nascimento, Salvador, Felipe Scassi, Santos, Robert Andreata, Zanotto, Paolo Marinho de Andrade, Romano, Camila Malta, Amorim, Jaime Henrique, Ferreira, Luís Carlos de Souza

“…Dengue fever is caused by any of the four known dengue virus serotypes (DENV1 to DENV4) that affect millions of people worldwide, causing a significant number…”
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Adjuvant-Mediated Epitope Specificity and Enhanced Neutralizing Activity of Antibodies Targeting Dengue Virus Envelope Protein by Maeda, Denicar Lina Nascimento Fabris, Batista, Milene Tavares, Pereira, Lennon Ramos, de Jesus Cintra, Mariana, Amorim, Jaime Henrique, Mathias-Santos, Camila, Pereira, Sara Araújo, Boscardin, Silvia Beatriz, Silva, Sandriana Dos Ramos, Faquim-Mauro, Eliana L, Silveira, Vanessa Barbosa, Oliveira, Danielle Bruna Leal, Johnston, Stephen Albert, Ferreira, Luís Carlos de Souza, Rodrigues, Juliana Falcão

“…The heat-labile toxins (LT) produced by enterotoxigenic display adjuvant effects to coadministered antigens, leading to enhanced production of serum…”
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Nanovaccine based on self-assembling nonstructural protein 1 boosts antibody responses to Zika virus by Favaro, Marianna Teixeira Pinho, Rodrigues-Jesus, Monica Josiane, Venceslau-Carvalho, Alexia Adrianne, Alves, Rúbens Prince Dos Santos, Pereira, Lennon Ramos, Pereira, Samuel Santos, Andreata-Santos, Robert, de Souza Ferreira, Luís Carlos

“…Self-assembling proteins may be generated after the addition of short specific amino acid sequences at both the N- and C-terminal ends. To date, this approach…”
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