Search Results - "Ferreira, Julio C.B."

Nitroglycerin Use in Myocardial Infarction Patients: Risks and Benefits by Ferreira, Julio C.B., Mochly-Rosen, Daria

“…Acute myocardial infarction (MI) and its sequelae are leading causes of morbidity and mortality worldwide. Nitroglycerin (glyceryl trinitrate [GTN]) remains a…”
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pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise by Reddy, Anita, Bozi, Luiz H.M., Yaghi, Omar K., Mills, Evanna L., Xiao, Haopeng, Nicholson, Hilary E., Paschini, Margherita, Paulo, Joao A., Garrity, Ryan, Laznik-Bogoslavski, Dina, Ferreira, Julio C.B., Carl, Christian S., Sjøberg, Kim A., Wojtaszewski, Jørgen F.P., Jeppesen, Jacob F., Kiens, Bente, Gygi, Steven P., Richter, Erik A., Mathis, Diane, Chouchani, Edward T.

“…In response to skeletal muscle contraction during exercise, paracrine factors coordinate tissue remodeling, which underlies this healthy adaptation. Here we…”
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Mitochondria as a source of reactive oxygen and nitrogen species: from molecular mechanisms to human health by Figueira, Tiago R, Barros, Mario H, Camargo, Anamaria A, Castilho, Roger F, Ferreira, Julio C B, Kowaltowski, Alicia J, Sluse, Francis E, Souza-Pinto, Nadja C, Vercesi, Anibal E

“…Mitochondrially generated reactive oxygen species are involved in a myriad of signaling and damaging pathways in different tissues. In addition, mitochondria…”
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A Personalized Medicine Approach for Asian Americans with the Aldehyde Dehydrogenase 22 Variant by Gross, Eric R, Zambelli, Vanessa O, Small, Bryce A, Ferreira, Julio C.B, Chen, Che-Hong, Mochly-Rosen, Daria

“…Asian Americans are one of the fastest-growing populations in the United States. A relatively large subset of this population carries a unique loss-of-function…”
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Acute inhibition of excessive mitochondrial fission after myocardial infarction prevents long-term cardiac dysfunction by Disatnik, Marie-Hélène, Ferreira, Julio C B, Campos, Juliane Cruz, Gomes, Kátia Sampaio, Dourado, Paulo M M, Qi, Xin, Mochly-Rosen, Daria

“…Ischemia and reperfusion (IR) injury remains a major cause of morbidity and mortality and multiple molecular and cellular pathways have been implicated in this…”
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Aldehydic load and aldehyde dehydrogenase 2 profile during the progression of post-myocardial infarction cardiomyopathy: Benefits of Alda-1 by Gomes, Katia M.S, Bechara, Luiz R.G, Lima, Vanessa M, Ribeiro, Márcio A.C, Campos, Juliane C, Dourado, Paulo M, Kowaltowski, Alicia J, Mochly-Rosen, Daria, Ferreira, Julio C.B

“…Abstract Background/objectives We previously demonstrated that reducing cardiac aldehydic load by aldehyde dehydrogenase 2 (ALDH2), a mitochondrial enzyme…”
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Endoplasmic reticulum stress impairs cardiomyocyte contractility through JNK-dependent upregulation of BNIP3 by Bozi, Luiz H.M., Takano, Ana P.C., Campos, Juliane C., Rolim, Natale, Dourado, Paulo M.M., Voltarelli, Vanessa A., Wisløff, Ulrik, Ferreira, Julio C.B., Barreto-Chaves, Maria L.M., Brum, Patricia C.

“…Disruption of endoplasmic reticulum (ER) homeostasis is a common feature of cardiac diseases. However, the signaling events involved in ER stress-induced…”
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Impact of exercise training on redox signaling in cardiovascular diseases by Campos, Juliane C., Gomes, Kátia M.S., Ferreira, Julio C.B.

“…•Oxidant stress has an adverse impact on the pathophysiology of cardiovascular diseases.•Redox signaling regulates exercise-training-mediated…”
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Novel and prevalent non-East Asian ALDH2 variants; Implications for global susceptibility to aldehydes’ toxicity by Chen, Che-Hong, Ferreira, Julio C.B., Joshi, Amit U., Stevens, Matthew C., Li, Sin-Jin, Hsu, Jade H.-M., Maclean, Rory, Ferreira, Nikolas D., Cervantes, Pilar R., Martinez, Diana D., Barrientos, Fernando L., Quintanares, Gibran H.R., Mochly-Rosen, Daria

“…Aldehyde dehydrogenase 2 (ALDH2) catalyzes the detoxification of aliphatic aldehydes, including acetaldehyde. About 45% of Han Chinese (East Asians),…”
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Comment on: “Aldehyde dehydrogenases contribute to skeletal muscle homeostasis in healthy, aging, and Duchenne muscular dystrophy patients” by Etienne et al by Campos, Juliane C., Chen, Che‐Hong, Ferreira, Julio C.B.

“…[...]the assay to sort ALDH‐enriched cells uses the molecule dimethylamino‐benzaldehyde (DEAB), as an inhibitor of ALDH (negative control). [...]determining…”
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Pharmacological inhibition of βIIPKC is cardioprotective in late-stage hypertrophy by Ferreira, Julio C.B, Koyanagi, Tomoyoshi, Palaniyandi, Suresh S, Fajardo, Giovanni, Churchill, Eric N, Budas, Grant, Disatnik, Marie-Helene, Bernstein, Daniel, Brum, Patricia C, Mochly-Rosen, Daria

“…Abstract We previously found that in the hearts of hypertensive Dahl salt-sensitive rats, βIIPKC levels increase during the transition from compensated cardiac…”
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Intracellular mechanisms of specific β-adrenoceptor antagonists involved in improved cardiac function and survival in a genetic model of heart failure by Bartholomeu, Jan B, Vanzelli, Andréa S, Rolim, Natale P.L, Ferreira, Julio C.B, Bechara, Luiz R.G, Tanaka, Leonardo Y, Rosa, Kaleizu T, Alves, Márcia M, Medeiros, Alessandra, Mattos, Katt C, Coelho, Marcele A, Irigoyen, Maria C, Krieger, Eduardo M, Krieger, Jose E, Negrão, Carlos E, Ramires, Paulo R, Guatimosim, Silvia, Brum, Patricia C

“…Abstract β-blockers, as class, improve cardiac function and survival in heart failure (HF). However, the molecular mechanisms underlying these beneficial…”
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RETRACTED: Angiotensin receptor blockade improves the net balance of cardiac Ca2+ handling-related proteins in sympathetic hyperactivity-induced heart failure by Ferreira, Julio C.B., Moreira, Jose B.N., Campos, Juliane C., Pereira, Marcelo G., Mattos, Katt C., Coelho, Marcele A., Brum, Patricia C.

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Cardiac neurohumoral control during early and late stage of heart failure in α2A /α2c adrenoceptor KO mice by Ferreira, Julio C.B, Evangelista, Fabiana S, Bacurau, line V, Oliveira, Edilamar M, Krieger, Jose E, Brum, Patricia C

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Ultra-sensitive Quantification of Carnosine-4-Hydroxy-2-hexenal Adduct in Mice Heart Using On-line Liquid Chromatography-Electrospray Tandem Mass Spectrometry Assay by Vargas, Bianca Scigliano, Menezes, Thiago N., Ferreira, Julio C.B., Di Mascio, Paolo, Medeiros, Marisa H.G.

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Treatment strategies for glucose-6-phosphate dehydrogenase deficiency: past and future perspectives by Garcia, Adriana A., Koperniku, Ana, Ferreira, Julio C.B., Mochly-Rosen, Daria

“…Glucose-6-phosphate dehydrogenase (G6PD) maintains redox balance in a variety of cell types and is essential for erythrocyte resistance to oxidative stress…”
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Mitofusin 1 and 2 deletion results in extensive mitochondria-ER/SR remodeling and compromises skeletal muscle function by Scheffer, Débora L., Bechara, Luiz R.G., Ribeiro, Márcio A.C., Meneses, Jones R.L., Liang, Yusheng, Qi, Ling, Ferreira, Julio C.B.

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Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Phosphorylation by Protein Kinase Cδ (PKCδ) Inhibits Mitochondria Elimination by Lysosomal-like Structures following Ischemia and Reoxygenation-induced Injury by Yogalingam, Gouri, Hwang, Sunhee, Ferreira, Julio C.B., Mochly-Rosen, Daria

“…After cardiac ischemia and reperfusion or reoxygenation (I/R), damaged mitochondria propagate tissue injury by promoting cell death. One possible mechanism to…”
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Mitochondrially-targeted treatment strategies by Bozi, Luiz H.M., Campos, Juliane C., Zambelli, Vanessa O., Ferreira, Nikolas D., Ferreira, Julio C.B.

“…Disruption of mitochondrial function is a common feature of inherited mitochondrial diseases (mitochondriopathies) and many other infectious and non-infectious…”
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Mitochondrial Unfolded Protein Response (UPRmt) Activation in Cardiac Diseases by Bozi, Luiz H.M., Campos, Juliane C., Gross, Eric R., Ferreira, Julio C.B.

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