Search Results - "Ferreira, E I"
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1
Nitric oxide: state of the art in drug design
Published in Current medicinal chemistry (2012)“…Since the great discovery of Furchgott, Ignarro and Murad in the late 90's, nitric oxide (NO) is considered one of the most versatile endogenous molecules,…”
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2
Synthesis and characterization of membranes obtained by graft copolymerization of 2-hydroxyethyl methacrylate and acrylic acid onto chitosan
Published in International journal of pharmaceutics (09-03-2006)“…Chitosan based membranes to be applied on wound healing as topical drug delivery systems were developed by graft copolymerization of acrylic acid (AA) and…”
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3
Peptide dendrimers: drug/gene delivery and other approaches
Published in Canadian journal of chemistry (01-09-2017)“…Dendrimers are versatile hyperbranched molecules, which have deserved attention especially for their potential in many applications, including biological…”
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4
Sound exposure and its beneficial effects on embryonic growth and hatching of broiler chicks
Published in British poultry science (02-01-2020)“…1. The physical factors that involve artificial incubation determine embryonic growth and hatching of broiler chicks, and have important implications for the…”
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5
Voltammetric behavior of benznidazole at a DNA-electrochemical biosensor
Published in Journal of pharmaceutical and biomedical analysis (01-07-2002)“…Benznidazole is a drug used commonly as a therapeutic agent against Chagas’ disease in Brazil. To clarify the cytotoxic action of benznidazole the…”
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6
A duplicated nitrotienyl derivative with antimycobacterial activity: synthesis, X-ray crystallography, biological and mutagenic activity tests
Published in European journal of medicinal chemistry (01-10-2006)“…A duplicated nitrotienyl derivative was obtained as a by-product from the synthesis of a proposed molecular hybrid of a nitrotienyl derivative and isoniazid…”
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7
An approach for the rational design of new antituberculosis agents
Published in Current drug targets (01-12-2001)“…Tuberculosis (TB) kills more youth and adults than any other infectious disease in the world today. The emergence of new strains of Mycobacterium tuberculosis…”
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8
Advances in prodrug design
Published in Mini reviews in medicinal chemistry (01-10-2005)“…The background of prodrug design is presented herein as the basis for introducing new and advanced latent systems, taking into account mainly the versatility…”
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9
Potential Tuberculostatic Agents: Micelle-Forming Copolymer Poly(ethylene glycol)-Poly(aspartic acid) Prodrug with Isoniazid
Published in Archiv der Pharmazie (Weinheim) (01-06-2001)“…With the objective of obtaining slow‐acting isoniazid derivatives, of potential use as chemoprophylactics or chemotherapeutics in tuberculosis, the…”
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10
Synthesis and in vitro evaluation of potential antichagasic dipeptide prodrugs of primaquine
Published in Journal of pharmaceutical sciences (01-10-1997)“…American trypanosomiasis (Chagas' disease) is an endemic parasitic disease afflicting more than 20 million people in Latin America. Currently, therapy is…”
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11
Antimalarial effect in vitro and lack of modulating effect of desipramine and imipramine
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01-11-1997)“…Based on previous studies in vitro of the modulating effect of desipramine on chloroquine-resistance of Plasmodium falciparum, the effect of desipramine and…”
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Journal Article Conference Proceeding -
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Rapid test for the evaluation of the activity of the prodrug hydroxymethylnitrofurazone in the processing of Trypanosoma cruzi messenger RNAs
Published in Brazilian journal of medical and biological research (01-01-2007)“…No fully effective treatment has been developed since the discovery of Chagas' disease by Carlos Chagas in 1909. Since drug-resistant Trypanosoma cruzi strains…”
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13
Thermal Characterization of Chitosan-Grafted Membranes to be Used as Wound Dressings
Published in Journal of carbohydrate chemistry (01-05-2006)“…Six different membranes previously prepared by the authors by graft copolymerization of acrylic acid (AA) and 2-hydroxyethylmethacrylate (HEMA) onto chitosan…”
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14
In vitro chloroquine resistance modulation study on fresh isolates of Brazilian Plasmodium falciparum: intrinsic antimalarial activity of phenothiazine drugs
Published in Memórias do Instituto Oswaldo Cruz (01-10-2002)“…Phenothiazine drugs - fluphenazine, chlorpromazine, methotrimeprazine and trifluoperazine - were evaluated as modulating agents against Brazilian…”
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15
Dissociation and electrooxidation of primaquine diphosphate as an approach to the study of anti-chagas prodrugs mechanism of action
Published in Bioelectrochemistry (Amsterdam, Netherlands) (2001)“…This paper describes the voltammetric behavior of primaquine as a previous support to the further understanding of the delivery and action mechanisms of its…”
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16
Leishmaniasis phytotherapy. Nature's leadership against an ancient disease
Published in Fitoterapia (01-08-2001)“…The use of phytotherapy to treat human diseases has its roots in pre-historical times. Despite the modern advances achieved in the field of synthetic…”
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Book Review Journal Article -
17
Quantitative structure–activity relationships for a series of inhibitors of cruzain from Trypanosoma cruzi: Molecular modeling, CoMFA and CoMSIA studies
Published in Journal of molecular graphics & modelling (01-08-2009)“…Human parasitic diseases are the foremost threat to human health and welfare around the world. Trypanosomiasis is a very serious infectious disease against…”
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18
Rapid test for the evaluation of the activity of the prodrug hydroxymethylnitrofurazone in the processing of Trypanosoma cruzi messenger RNAs
Published in Brazilian journal of medical and biological research (01-01-2007)“…No fully effective treatment has been developed since the discovery of Chagas' disease by Carlos Chagas in 1909. Since drug-resistant Trypanosoma cruzi strains…”
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19
Preparation of Polymeric Micelles for use as Carriers of Tuberculostatic Drugs
Published in Tropical journal of pharmaceutical research (19-12-2007)Get full text
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20
Targeting Groups Employed in Selective Dendrons and Dendrimers
Published in Pharmaceutics (08-11-2018)“…The design of compounds with directed action to a defined organ or tissue is a very promising approach, since it can decrease considerably the toxicity of the…”
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