Search Results - "Ferreira, Duarte M. S."

miR-143 overexpression impairs growth of human colon carcinoma xenografts in mice with induction of apoptosis and inhibition of proliferation by Borralho, Pedro M, Simões, André E S, Gomes, Sofia E, Lima, Raquel T, Carvalho, Tânia, Ferreira, Duarte M S, Vasconcelos, Maria H, Castro, Rui E, Rodrigues, Cecília M P

“…MicroRNAs (miRNAs) are aberrantly expressed in human cancer and involved in the (dys)regulation of cell survival, proliferation, differentiation and death…”
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c-Jun N-Terminal Kinase 1/c-Jun Activation of the p53/MicroRNA 34a/Sirtuin 1 Pathway Contributes to Apoptosis Induced by Deoxycholic Acid in Rat Liver by Ferreira, Duarte M. S., Afonso, Marta B., Rodrigues, Pedro M., Simão, André L., Pereira, Diane M., Borralho, Pedro M., Rodrigues, Cecília M. P., Castro, Rui E.

“…Classifications Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force by Ferreira, Duarte M S, Cheng, Arthur J, Agudelo, Leandro Z, Cervenka, Igor, Chaillou, Thomas, Correia, Jorge C, Porsmyr-Palmertz, Margareta, Izadi, Manizheh, Hansson, Alicia, Martínez-Redondo, Vicente, Valente-Silva, Paula, Pettersson-Klein, Amanda T, Estall, Jennifer L, Robinson, Matthew M, Nair, K Sreekumaran, Lanner, Johanna T, Ruas, Jorge L

“…Skeletal muscle mass and strength are crucial determinants of health. Muscle mass loss is associated with weakness, fatigue, and insulin resistance. In fact,…”
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Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid by Castro, Rui E, Ferreira, Duarte M S, Zhang, Xiaoxiao, Borralho, Pedro M, Sarver, Aaron L, Zeng, Yan, Steer, Clifford J, Kren, Betsy T, Rodrigues, Cecília M P

“…New gene regulation study tools such as microRNA (miRNA or miR) analysis may provide unique insights into the remarkable ability of the liver to regenerate. In…”
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Liver and muscle in morbid obesity: the interplay of fatty liver and insulin resistance by Machado, Mariana Verdelho, Ferreira, Duarte M S, Castro, Rui E, Silvestre, Ana Rita, Evangelista, Teresinha, Coutinho, João, Carepa, Fátima, Costa, Adília, Rodrigues, Cecília M P, Cortez-Pinto, Helena

“…Nonalcoholic fatty liver disease (NAFLD) can be seen as a manifestation of overnutrition. The muscle is a central player in the adaptation to energy overload,…”
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Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance by Agudelo, Leandro Z., Ferreira, Duarte M. S., Dadvar, Shamim, Cervenka, Igor, Ketscher, Lars, Izadi, Manizheh, Zhengye, Liu, Furrer, Regula, Handschin, Christoph, Venckunas, Tomas, Brazaitis, Marius, Kamandulis, Sigitas, Lanner, Johanna T., Ruas, Jorge L.

“…The coactivator PGC-1α1 is activated by exercise training in skeletal muscle and promotes fatigue-resistance. In exercised muscle, PGC-1α1 enhances the…”
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Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism by Massart, Julie, Sjögren, Rasmus J. O., Egan, Brendan, Garde, Christian, Lindgren, Magnus, Gu, Weifeng, Ferreira, Duarte M. S., Katayama, Mutsumi, Ruas, Jorge L., Barrès, Romain, O’Gorman, Donal J., Zierath, Juleen R., Krook, Anna

“…Skeletal muscle is a highly adaptable tissue and remodels in response to exercise training. Using short RNA sequencing, we determine the miRNA profile of…”
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Modeling the transport of nuclear proteins along single skeletal muscle cells by Taylor-Weiner, Hermes, Grigsby, Christopher L., Ferreira, Duarte M. S., Dias, José M., Stevens, Molly M., Ruas, Jorge L., Teixeira, Ana I.

“…Skeletal muscle cells contain hundreds of myonuclei within a shared cytoplasm, presenting unique challenges for regulating gene expression. Certain…”
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Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling by Naia, Luana, Pinho, Catarina M, Dentoni, Giacomo, Liu, Jianping, Leal, Nuno Santos, Ferreira, Duarte M S, Schreiner, Bernadette, Filadi, Riccardo, Fão, Lígia, Connolly, Niamh M C, Forsell, Pontus, Nordvall, Gunnar, Shimozawa, Makoto, Greotti, Elisa, Basso, Emy, Theurey, Pierre, Gioran, Anna, Joselin, Alvin, Arsenian-Henriksson, Marie, Nilsson, Per, Rego, A Cristina, Ruas, Jorge L, Park, David, Bano, Daniele, Pizzo, Paola, Prehn, Jochen H M, Ankarcrona, Maria

“…Mitochondrial dysfunction is a common feature of aging, neurodegeneration, and metabolic diseases. Hence, mitotherapeutics may be valuable disease modifiers…”
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Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans by Valente-Silva, Paula, Cervenka, Igor, Ferreira, Duarte M. S., Correia, Jorge C., Edman, Sebastian, Horwath, Oscar, Heng, Benjamin, Chow, Sharron, Jacobs, Kelly R., Guillemin, Gilles J., Blomstrand, Eva, Ruas, Jorge L.

“…The kynurenine pathway of tryptophan (TRP) degradation (KP) generates metabolites with effects on metabolism, immunity, and mental health. Endurance exercise…”
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Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression by Agudelo, Leandro Z., Femenía, Teresa, Orhan, Funda, Porsmyr-Palmertz, Margareta, Goiny, Michel, Martinez-Redondo, Vicente, Correia, Jorge C., Izadi, Manizheh, Bhat, Maria, Schuppe-Koistinen, Ina, Pettersson, Amanda T., Ferreira, Duarte M.S., Krook, Anna, Barres, Romain, Zierath, Juleen R., Erhardt, Sophie, Lindskog, Maria, Ruas, Jorge L.

“…Depression is a debilitating condition with a profound impact on quality of life for millions of people worldwide. Physical exercise is used as a treatment…”
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Cell death targets and potential modulators in Alzheimer's disease by Castro, Rui E, Santos, Maria M M, Glória, Paulo M C, Ribeiro, Carlos J A, Ferreira, Duarte M S, Xavier, Joana M, Moreira, Rui, Rodrigues, Cecília M P

“…Apoptosis is now recognized as a normal feature in the development of the nervous system and may also play a role in neurodegenerative disorders, such as…”
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miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease by Castro, Rui E, Ferreira, Duarte M.S, Afonso, Marta B, Borralho, Pedro M, Machado, Mariana V, Cortez-Pinto, Helena, Rodrigues, Cecília M.P

“…Background & Aims Non-alcoholic fatty liver disease (NAFLD) comprises a spectrum of stages from simple steatosis to non-alcoholic steatohepatitis (NASH)…”
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Intercellular: local and systemic actions of skeletal muscle PGC-1s by Correia, Jorge C, Ferreira, Duarte M.S, Ruas, Jorge L

“…Highlights • PGC-1 coactivators mediate many of the known effects of exercise in skeletal muscle. • PGC-1s improve skeletal muscle mass, energy metabolism, and…”
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Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes by Martínez-Redondo, Vicente, Jannig, Paulo R., Correia, Jorge C., Ferreira, Duarte M.S., Cervenka, Igor, Lindvall, Jessica M., Sinha, Indranil, Izadi, Manizheh, Pettersson-Klein, Amanda T., Agudelo, Leandro Z., Gimenez-Cassina, Alfredo, Brum, Patricia C., Dahlman-Wright, Karin, Ruas, Jorge L.

“…Endurance and resistance exercise training induces specific and profound changes in the skeletal muscle transcriptome. Peroxisome proliferator-activated…”
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Mitochondrial NDUFA4L2 is a novel regulator of skeletal muscle mass and force by Liu, Zhengye, Chaillou, Thomas, Santos Alves, Estela, Mader, Theresa, Jude, Baptiste, Ferreira, Duarte M. S., Hynynen, Heidi, Cheng, Arthur J., Jonsson, William O., Pironti, Gianluigi, Andersson, Daniel C., Kenne, Ellinor, Ruas, Jorge L., Tavi, Pasi, Lanner, Johanna T.

“…The hypoxia‐inducible nuclear‐encoded mitochondrial protein NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4‐like 2 (NDUFA4L2) has been demonstrated to…”
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Revisiting the metabolic syndrome and paving the way for microRNAs in non‐alcoholic fatty liver disease by Ferreira, Duarte M. S., Simão, André L., Rodrigues, Cecília M. P., Castro, Rui E.

“…Non‐alcoholic fatty liver disease (NAFLD) comprises a spectrum of stages from simple steatosis to non‐alcoholic steatohepatitis, which can progress to…”
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Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation by Mills, Richard, Taylor-Weiner, Hermes, Correia, Jorge C, Agudelo, Leandro Z, Allodi, Ilary, Kolonelou, Christina, Martinez-Redondo, Vicente, Ferreira, Duarte M S, Nichterwitz, Susanne, Comley, Laura H, Lundin, Vanessa, Hedlund, Eva, Ruas, Jorge L, Teixeira, Ana I

“…We examined whether skeletal muscle overexpression of PGC-1α1 or PGC-1α4 affected myokine secretion and neuromuscular junction (NMJ) formation. A microfluidic…”
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Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation by Agudelo, Leandro Z., Ferreira, Duarte M.S., Cervenka, Igor, Bryzgalova, Galyna, Dadvar, Shamim, Jannig, Paulo R., Pettersson-Klein, Amanda T., Lakshmikanth, Tadepally, Sustarsic, Elahu G., Porsmyr-Palmertz, Margareta, Correia, Jorge C., Izadi, Manizheh, Martínez-Redondo, Vicente, Ueland, Per M., Midttun, Øivind, Gerhart-Hines, Zachary, Brodin, Petter, Pereira, Teresa, Berggren, Per-Olof, Ruas, Jorge L.

“…The role of tryptophan-kynurenine metabolism in psychiatric disease is well established, but remains less explored in peripheral tissues. Exercise training…”
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Revisiting the metabolic syndrome and paving the way for micro RNA s in non‐alcoholic fatty liver disease by Ferreira, Duarte M. S., Simão, André L., Rodrigues, Cecília M. P., Castro, Rui E.

“…Non‐alcoholic fatty liver disease ( NAFLD ) comprises a spectrum of stages from simple steatosis to non‐alcoholic steatohepatitis, which can progress to…”
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