Search Results - "Ferreira, Caroline B"
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Phox2b mutation mediated by Atoh1 expression impaired respiratory rhythm and ventilatory responses to hypoxia and hypercapnia
Published in eLife (17-11-2022)“…Mutations in the transcription factor Phox2b cause congenital central hypoventilation syndrome (CCHS). The syndrome is characterized by hypoventilation and…”
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Increased sympathetic responses induced by chronic obstructive sleep apnea are caused by sleep fragmentation
Published in Journal of applied physiology (1985) (01-07-2020)“…Obstructive sleep apnea (OSA) is often associated with sympathetic overactivity and hypertension. These associations are mainly attributed to hypoxia acting on…”
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Nucleus of the solitary tract neuronal degeneration and impaired hypoxia response in a model of Parkinson's disease
Published in Experimental neurology (01-10-2024)“…Parkinson's disease (PD) involves the degeneration of dopaminergic neurons in the substantia nigra (SNpc) and manifests with both classic and non-classic motor…”
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Brain Pathways in Blood Pressure Regulation
Published in Hypertension (Dallas, Tex. 1979) (01-03-2024)Get full text
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Chronic apnea during REM sleep increases arterial pressure and sympathetic modulation in rats
Published in Sleep (New York, N.Y.) (01-05-2021)“…Abstract Study Objectives Obstructive sleep apnea can induce hypertension. Apneas in REM may be particularly problematic: they are independently associated…”
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Respiratory deficits in a female rat model of Parkinson's disease
Published in Experimental physiology (01-11-2022)“…New Findings What is the central question of this study? How does the 6‐hydroxydopamine (6‐OHDA)‐induced Parkinson's disease model affect the respiratory…”
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Airway obstruction produces widespread sympathoexcitation: role of hypoxia, carotid chemoreceptors, and NTS neurotransmission
Published in Physiological reports (01-02-2018)“…Obstructive sleep apnea (OSA) is the most common respiratory disturbance of sleep and is closely associated to cardiovascular diseases. In humans, apnea…”
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Autoregulation of blood flow drives early hypotension in a rat model of systemic inflammation induced by bacterial lipopolysaccharide
Published in PNAS nexus (01-02-2023)“…Uncontrolled vasodilation is known to account for hypotension in the advanced stages of sepsis and other systemic inflammatory conditions, but the mechanisms…”
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Abstract P058: Regional Sympathetic Activation Induced by Obstructive Apnea
Published in Hypertension (Dallas, Tex. 1979) (01-09-2015)“…Abstract only Obstructive sleep apnea increases muscle sympathetic nerve activity (SNA) in humans that contributes to cardiovascular dysfunction including…”
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Phox2b Mutation Mediated by Atoh1 Expression Impaired Respiratory Rhythm and Ventilatory Responses to Hypoxia and Hypercapnia
Published in The FASEB journal (01-05-2022)“…Retrotrapezoid nucleus (RTN) neurons are involved in central chemoreception and respiratory control. Lineage tracing studies demonstrate RTN neurons to be…”
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Obstructive Apnea Induces Similar Sympathetic Activation Across Several End Organs Independently of Chemoreceptors Afferents
Published in The FASEB journal (01-04-2016)“…Abstract only Obstructive sleep apnea increases muscle sympathetic nerve activity (SNA) in humans that contributes to cardiovascular dysfunction including…”
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Brainstem areas activated by intermittent apnea in awake unrestrained rats
Published in The FASEB journal (01-04-2012)“…Abstract only Patients with obstructive sleep apnoea experience repeated hypoxia, hypercapnia, and changes in pulmonary afferent traffic, resulting in…”
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