Search Results - "Ferreira, Carlos G"

Randomized Phase III Trial of Single-Agent Pemetrexed Versus Carboplatin and Pemetrexed in Patients With Advanced Non–Small-Cell Lung Cancer and Eastern Cooperative Oncology Group Performance Status of 2 by ZUKIN, Mauro, BARRIOS, Carlos H, DA ROCHA BALDOTTO, Clarissa Serodio, METON VIEIRA, Fernando, SMALL, Isabele A, FERREIRA, Carlos G, LILENBAUM, Rogerio C, PEREIRA, Jose Rodrigues, DE ALBUQUERQUE RIBEIRO, Ronaldo, DE MENDONCA BEATO, Carlos Augusto, DO NASCIMENTO, Yeni Neron, MURAD, Andre, FRANKE, Fabio A, PRECIVALE, Maristela, DE LIMA ARAUJO, Luiz Henrique

“…To compare single-agent pemetrexed (P) versus the combination of carboplatin and pemetrexed (CP) in first-line therapy for patients with advanced…”
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The Value of Biomarkers in Optimizing the Use of Immuno-oncologic Therapy by Ferreira, Carlos G, Nicolini, Andrea, Dalurzo, Liliana, Stefani, Stephen, Teich, Vanessa, Leighl, Natasha

“…The development of therapies that restore or activate the host immune response - the socalled "immuno-oncologic" therapy - has improved the survival of some…”
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Splice variants in the proteome: a promising and challenging field to targeted drug discovery by Tavares, Raphael, Scherer, Nicole M., Ferreira, Carlos G., Costa, Fabricio F., Passetti, Fabio

“…•Many human genes are affected by alternative splicing.•There are several alternative spliced transcripts with their structures already solved.•Alternative…”
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Prognosis of lung cancer patients with life-threatening complications by Soares, Márcio, Darmon, Michael, Salluh, Jorge I F, Ferreira, Carlos G, Thiéry, Guillaume, Schlemmer, Benoit, Spector, Nelson, Azoulay, Élie

“…The management of patients with lung cancer has improved recently, and many of them will require admission to the ICU. The aims of this study were to determine…”
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Phase I/II Study of Erlotinib Combined With Cisplatin and Radiotherapy in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck by Herchenhorn, Daniel, M.D, Dias, Fernando L., M.D., Ph.D, Viegas, Célia M.P., M.D., M.Sc., Ph.D, Federico, Miriam H., M.D., Ph.D, Araújo, Carlos Manoel M., M.D., Ph.D, Small, Isabelle, M.Sc, Bezerra, Marcos, M.D, Fontão, Karina, M.D, Knust, Renata E., R.N, Ferreira, Carlos G., M.D., Ph.D, Martins, Renato G., M.D., M.P.H

“…Purpose Erlotinib, an oral tyrosine kinase inhibitor, is active against head-and-neck squamous cell carcinoma (HNSCC) and possibly has a synergistic…”
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Phase I Trial of Erlotinib Combined with Cisplatin and Radiotherapy for Patients with Locally Advanced Cervical Squamous Cell Cancer by NOGUEIRA-RODRIGUES, Angélica, DO CARMO, Claudio C, SMALL, Isabele A, FERREIRA, Carlos G, VIEGAS, Célia, ERLICH, Felipe, CAMISAO, Claudia, FONTAO, Karina, LIMA, Roberta, HERCHENHORN, Daniel, MARTINS, Renato G, MORALEZ, Giulliana M

“…Purpose: This phase I trial was aimed to determine the maximum tolerated dose and related toxicity of erlotinib (E) when administered concurrently with…”
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Paclitaxel Triggers Cell Death Primarily via Caspase-independent Routes in the Non-Small Cell Lung Cancer Cell Line NCI-H460 by HUISMAN, Cynthia, FERREIRA, Carlos G, BROKER, Linda E, RODRIGUEZ, Jose A, SMIT, Egbert F, POSTMUS, Pieter E, KRUYT, Frank A. E, GIACCONE, Giuseppe

“…Purpose: Here we report on the role of mitochondria, death receptors (DRs), and caspases in exerting the cytotoxic effect of clinically relevant concentrations…”
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Long-term survival of a randomized phase III trial of head and neck cancer patients receiving concurrent chemoradiation therapy with or without low-level laser therapy (LLLT) to prevent oral mucositis by Antunes, Héliton S, Herchenhorn, Daniel, Small, Isabele A, Araújo, Carlos M.M, Viégas, Celia Maria Pais, de Assis Ramos, Gabriela, Dias, Fernando L, Ferreira, Carlos G

“…Highlights • We investigate the impact of low-level laser therapy on the OS, DFS, PFS. • We report data suggesting that morbidity was lower in the Laser Group…”
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Perspectives on emerging technologies, personalised medicine, and clinical research for cancer control in Latin America and the Caribbean by Werutsky, Gustavo, Barrios, Carlos H, Cardona, Andres F, Albergaria, André, Valencia, Alfonso, Ferreira, Carlos G, Rolfo, Christian, de Azambuja, Evandro, Rabinovich, Gabriel A, Sposetti, Georgina, Arrieta, Oscar, Dienstmann, Rodrigo, Rebelatto, Taiane F, Denninghoff, Valeria, Aran, Veronica, Cazap, Eduardo

“…Challenges of health systems in Latin America and the Caribbean include accessibility, inequity, segmentation, and poverty. These challenges are similar in…”
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Efficient blockade of Akt signaling is a determinant factor to overcome resistance to matuzumab by Meira, Debora D, Almeida, Vitor H, Mororó, Jânio S, Caetano, Mauricio S, Nóbrega, Isabel P, Batista, Delano, Sternberg, Cinthya, Ferreira, Carlos G

“…Clinical studies have shown antineoplastic effectiveness of monoclonal antibodies (MAbs) against EGFR for different indications. Several MAbs directed to EGFR…”
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Phase 2 trial of erlotinib combined with cisplatin and radiotherapy in patients with locally advanced cervical cancer by Nogueira‐Rodrigues, Angelica, Moralez, Giulliana, Grazziotin, Rachele, Carmo, Claudio C., Small, Isabele A., Alves, Flavia V.G., Mamede, Marcelo, Erlich, Felipe, Viegas, Celia, Triginelli, Sergio A., Ferreira, Carlos G.

“…BACKGROUND Cisplatin‐based chemoradiation (CRT) is the standard treatment for patients with locally advanced cervical cancer. Epidermal growth factor receptor…”
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Phase III trial of low-level laser therapy to prevent oral mucositis in head and neck cancer patients treated with concurrent chemoradiation by Antunes, Heliton S, Herchenhorn, Daniel, Small, Isabele A, Araújo, Carlos M.M, Viégas, Celia Maria Pais, Cabral, Elida, Rampini, Mariana P, Rodrigues, Pedro C, Silva, Tereza G.P, Ferreira, Elza M.S, Dias, Fernando L, Ferreira, Carlos G

“…Abstract Background Oral mucositis (OM) is a complication of chemoradiotherapy treatment of head and neck squamous cell carcinoma (HNSCC) patients with no…”
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Carboplatin plus pemetrexed offers superior cost-effectiveness compared to pemetrexed in patients with advanced non-small cell lung cancer and performance status 2 by Schluckebier, Luciene, Garay, Osvaldo U, Zukin, Mauro, Ferreira, Carlos G

“…Highlights • Lung cancer with PS2 status is a common condition accounting around 40%. • Economic data is useful to complement data about safety and efficacy. •…”
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XAF1 mRNA expression improves progression-free and overall survival for patients with advanced bladder cancer treated with neoadjuvant chemotherapy by Pinho, Marcos B., MSc, Costas, Fernanda, B.S, Sellos, João, B.S, Dienstmann, Rodrigo, M.D, Andrade, Patricia B., M.D, Herchenhorn, Daniel, M.D, Peixoto, Fábio Afonso, M.D, Santos, Valdelice O., R.N, Small, Isabele A., MSc, Guimarães, Denise P., M.D., Ph.D, Ferreira, Carlos G., M.D., Ph.D

“…Abstract Purpose The aim of this study was to investigate whether mRNA expression of the apoptosis-associated genes, XAF1 and XIAP, in bladder cancer patients…”
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Cost-effectiveness of low-level laser therapy (LLLT) in head and neck cancer patients receiving concurrent chemoradiation by Antunes, Héliton S, Schluckebier, Luciene Fontes, Herchenhorn, Daniel, Small, Isabele A, Araújo, Carlos M.M, Viégas, Celia Maria Pais, Rampini, Mariana P, Ferreira, Elza M.S, Dias, Fernando L, Teich, Vanessa, Teich, Nelson, Ferreira, Carlos G

“…Highlights • We are the first to investigate the impact of LLLT on the cost of treatment those patients. • We report data suggesting that morbidity was lower…”
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A brick in the wall by Nogueira‐Rodrigues, Angelica, Ferreira, Carlos G.

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Discrepancies Between the Cost of Advanced Lung Cancer Treatment and How Much Is Reimbursed by the Brazilian Public Healthcare System by Kelner, Marina, Carvalho da Silva, Bruna, Montella, Tatiane, Aguiar, Jr, Pedro Nazareth, Lopes, Gilberto, Ferreira, Carlos G, De Marchi, Pedro

“…Lung cancer is the leading cause of cancer-related death worldwide, and most patients are diagnosed of advanced disease. Molecular-targeted therapy and…”
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Phase II trial of neoadjuvant gemcitabine and cisplatin in patients with resectable bladder carcinoma by Herchenhorn, Daniel, Dienstmann, Rodrigo, Peixoto, Fabio A, de Campos, Franz S, Santos, Valdelice O, Moreira, Denise M, Cardoso, Hedilene, Small, Isabele A, Ferreira, Carlos G

“…Gemcitabine and cisplatin (GC) is an active combination in the treatment of metastatic bladder cancer. We have prospectively analyzed the efficacy and…”
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Targeting epidermal growth factor receptor to optimize chemoradiotherapy in locally advanced head and neck cancer: has biology been taken into account? by Herchenhorn, Daniel, Ferreira, Carlos G

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A hierarchical network-oriented analysis of user participation in misinformation spread on WhatsApp by Nobre, Gabriel Peres, Ferreira, Carlos H.G., Almeida, Jussara M.

“…WhatsApp emerged as a major communication platform in many countries in the recent years. Despite offering only one-to-one and small group conversations,…”
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