Search Results - "Ferreira, Amália Santos"
-
1
Antileishmanial drugs activate inflammatory signaling pathways via toll-like receptors (docking approach) from Leishmania amazonensis-infected macrophages
Published in International immunopharmacology (01-08-2020)“…•AmB, GLU and pent present predicted affinity with different TLRs from L. amazonensis-infected macrophages.•Antileishmanial drugs activate main inflammatory…”
Get full text
Journal Article -
2
Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues
Published in International journal for parasitology -- drugs and drug resistance (01-12-2022)“…Malaria is among the tropical diseases that cause the most deaths in Africa. Around 500,000 malaria deaths are reported yearly among African children under the…”
Get full text
Journal Article -
3
Quinine and chloroquine: Potential preclinical candidates for the treatment of tegumentary Leishmaniasis
Published in Acta tropica (01-04-2024)“…•Inhibition of Leishmania growth was observed in vitro and in vivo after treatment with chloroquine.•Antimalarials demonstrated lower cytotoxicity than…”
Get full text
Journal Article -
4
Evaluation of the antileishmanial activity of biodegradable microparticles containing a hexanic eluate subfraction of Maytenus guianensis bark
Published in Experimental parasitology (01-10-2019)“…Leishmaniases, caused by Leishmania spp., are among the most prevalent infectious diseases in the world and their treatment may present high toxicity and…”
Get full text
Journal Article -
5
Antimalarial potential of leaves of Chenopodium ambrosioides L
Published in Parasitology research (1987) (01-11-2016)“…In an effort to identify novel therapeutic alternatives for the treatment of malaria, the present study evaluated the antimalarial effect of the crude…”
Get full text
Journal Article -
6
Drug-containing hydrophobic dressings as a topical experimental therapy for cutaneous leishmaniasis
Published in Journal of parasitic diseases (01-03-2020)“…Cutaneous leishmaniasis (CL), a clinical condition caused mainly by Leishmania amazonensis in Brazil, is characterized by topical, painless ulcers. The current…”
Get full text
Journal Article -
7
A natural cell-penetrating nanopeptide combined with pentavalent antimonial as experimental therapy against cutaneous leishmaniasis
Published in Experimental parasitology (01-10-2020)“…The inadequacy of available treatments for leishmaniasis has presented up to 40% therapeutic failure. This fact suggests an urgency in the discovery of new…”
Get full text
Journal Article -
8
The pentavalent antimonial therapy against experimental Leishmania amazonensis infection is more effective under the inhibition of the NF-κB pathway
Published in International immunopharmacology (01-09-2015)“…During Leishmania infection, host immune response is important to prevent the growth/survival of intracellular amastigotes. In this study, we evaluated in…”
Get full text
Journal Article -
9
Antileishmanial and Immunomodulatory Effect of Babassu-Loaded PLGA Microparticles: A Useful Drug Target to Leishmania amazonensis Infection
Published in Evidence-based complementary and alternative medicine (01-01-2018)“…The immunological and the anti-Leishmania amazonensis activity of babassu-loaded poly(lactic-co-glycolic acid) [PLGA] microparticles was evaluated. The…”
Get full text
Journal Article