Search Results - "Ferrauto, Giuseppe"

Effects of Cations on HPTS Fluorescence and Quantification of Free Gadolinium Ions in Solution; Assessment of Intracellular Release of Gd3+ from Gd-Based MRI Contrast Agents by Scarciglia, Angelo, Di Gregorio, Enza, Aime, Silvio, Ferrauto, Giuseppe

“…8-Hydroxypyrene-1,3,6-trisulfonate (HPTS) is a small, hydrophilic fluorescent molecule. Since the pKa of the hydroxyl group is close to neutrality and quickly…”
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In vivo maps of extracellular pH in murine melanoma by CEST-MRI by Delli Castelli, D, Ferrauto, Giuseppe, Cutrin, Juan Carlos, Terreno, Enzo, Aime, Silvio

“…Purpose A novel method based on the use of Yb‐HPDO3A as MRI Para‐CEST agent for in vivo pH mapping of the tumor region in a melanoma murine model is reported…”
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CEST‐MRI for glioma pH quantification in mouse model: Validation by immunohistochemistry by Ferrauto, Giuseppe, Di Gregorio, Enza, Auboiroux, Vincent, Petit, Manuel, Berger, François, Aime, Silvio, Lahrech, Hana

“…In glioma, the acidification of the extracellular tumor microenvironment drives proliferation, angiogenesis, immunosuppression, invasion and chemoresistance…”
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Toll-like receptor 2 promotes breast cancer progression and resistance to chemotherapy by Di Lorenzo, Antonino, Bolli, Elisabetta, Ruiu, Roberto, Ferrauto, Giuseppe, Di Gregorio, Enza, Avalle, Lidia, Savino, Aurora, Poggio, Pietro, Merighi, Irene Fiore, Riccardo, Federica, Brancaccio, Mara, Quaglino, Elena, Cavallo, Federica, Conti, Laura

“…Cancer stem cells (CSCs) are the main drivers of disease progression and chemotherapy resistance in breast cancer. Tumor progression and chemoresistance might…”
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Use of FCC-NMRD relaxometry for early detection and characterization of ex-vivo murine breast cancer by Di Gregorio, Enza, Ferrauto, Giuseppe, Lanzardo, Stefania, Gianolio, Eliana, Aime, Silvio

“…Breast Cancer is the most diffuse cancer among women and the treatment outcome is largely determined by its early detection. MRI at fixed magnetic field is…”
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Simultaneous MR imaging for tissue engineering in a rat model of stroke by Nicholls, Francesca J., Ling, Wen, Ferrauto, Giuseppe, Aime, Silvio, Modo, Michel

“…In situ tissue engineering within a stroke cavity is gradually emerging as a novel therapeutic paradigm. Considering the varied lesion topology within each…”
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Melanoma Prevention: Comparison of Different Screening Methods for the Selection of a High Risk Population by Dubbini, Nevio, Puddu, Antonella, Salimbeni, Grazia, Malloggi, Stefano, Gandini, Daniele, Massei, Pietro, Ferraùto, Giuseppe, Rubino, Tommaso, Ricci, Laura, Menchini, Giovanni, Celli, Marco, Ghilardi, Maurizia, Gianfaldoni, Roberto, Gianfaldoni, Serena, Nannipieri, Andrea, Romanini, Antonella

“…Guidelines recommend limiting melanoma screening in a population with known risk factors, but none indicates methods for efficient recruitment. The purpose of…”
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Eight-Coordinate, Stable Fe(II) Complex as a Dual 19F and CEST Contrast Agent for Ratiometric pH Imaging by Srivastava, Kriti, Ferrauto, Giuseppe, Young, Victor G, Aime, Silvio, Pierre, Valérie C

“…Accurate mapping of small changes in pH is essential to the diagnosis of diseases such as cancer. The difficulty in mapping pH accurately in vivo resides in…”
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Advanced cardiac chemical exchange saturation transfer (cardioCEST) MRI for in vivo cell tracking and metabolic imaging by Pumphrey, Ashley, Yang, Zhengshi, Ye, Shaojing, Powell, David K., Thalman, Scott, Watt, David S., Abdel-Latif, Ahmed, Unrine, Jason, Thompson, Katherine, Fornwalt, Brandon, Ferrauto, Giuseppe, Vandsburger, Moriel

“…An improved pre‐clinical cardiac chemical exchange saturation transfer (CEST) pulse sequence (cardioCEST) was used to selectively visualize paramagnetic CEST…”
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Optimizing the Relaxivity of MRI Probes at High Magnetic Field Strengths With Binuclear GdIII Complexes by Leone, Loredana, Ferrauto, Giuseppe, Cossi, Maurizio, Botta, Mauro, Tei, Lorenzo

“…The key criteria to optimize the relaxivity of a Gd(III) contrast agent at high fields (defined as the region ≥ 1.5 T) can be summarized as follows: (i) the…”
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A Simple and Fast Assay Based on Carboxyfluorescein-Loaded Liposome for Quantitative DNA Detection by Sforzi, Jacopo, Ferrauto, Giuseppe, Aime, Silvio, Geninatti Crich, Simonetta

“…The development of an innovative and easy way to run assays for the quantitative detection of DNA present in biological fluids (i.e., blood, urine, and saliva)…”
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Water Diffusion Modulates the CEST Effect on Tb(III)-Mesoporous Silica Probes by Carniato, Fabio, Ferrauto, Giuseppe, Muñoz-Úbeda, Mónica, Tei, Lorenzo

“…The anchoring of lanthanide(III) chelates on the surface of mesoporous silica nanoparticles (MSNs) allowed their investigation as magnetic resonance imaging…”
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Compartmentalized agents: A powerful strategy for enhancing the detection sensitivity of chemical exchange saturation transfer contrast by Ferrauto, Giuseppe, Terreno, Enzo

“…Since the very beginnings of the chemical exchange saturation transfer (CEST) technique, poor overall sensitivity has appeared to be one of its strongest…”
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Seeking for Innovation with Magnetic Resonance Imaging Paramagnetic Contrast Agents: Relaxation Enhancement via Weak and Dynamic Electrostatic Interactions with Positively Charged Groups on Endogenous Macromolecules by Stefania, Rachele, Palagi, Lorenzo, Di Gregorio, Enza, Ferrauto, Giuseppe, Dinatale, Valentina, Aime, Silvio, Gianolio, Eliana

“…Gd-L1 is a macrocyclic Gd-HPDO3A derivative functionalized with a short spacer to a trisulfonated pyrene. When compared to Gd-HPDO3A, the increased relaxivity…”
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Chitosan‐Based Nanogels Containing Ln 3+ Chelates (Ln=Gd, Dy) as T 1 and T 2 MRI Probes by Ricci, Marco, Carniato, Fabio, Tei, Lorenzo, Camorali, Sara, Ferrauto, Giuseppe, Botta, Mauro

“…Abstract Novel nanogels, characterized by high stability and incorporating macrocyclic chelates of Gd(III) and Dy(III), were synthesized and assessed for their…”
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Chitosan‐Based Nanogels Containing Ln3+ Chelates (Ln=Gd, Dy) as T1 and T2 MRI Probes by Ricci, Marco, Carniato, Fabio, Tei, Lorenzo, Camorali, Sara, Ferrauto, Giuseppe, Botta, Mauro

“…Novel nanogels, characterized by high stability and incorporating macrocyclic chelates of Gd(III) and Dy(III), were synthesized and assessed for their…”
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Re-evaluation of the water exchange lifetime value across red blood cell membrane by Gianolio, Eliana, Ferrauto, Giuseppe, Di Gregorio, Enza, Aime, Silvio

“…The water exchange lifetime (τi) through red blood cell (RBC) membranes can be measured by analyzing the water protons bi-exponential T1 and T2 curves when…”
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The interaction between iodinated X‐ray contrast agents and macrocyclic GBCAs provides a signal enhancement in T1‐weighted MR images: Insights into the renal excretion pathways of Gd‐HPDO3A and iodixanol in healthy mice by Di Gregorio, Enza, Arena, Francesca, Gianolio, Eliana, Ferrauto, Giuseppe, Aime, Silvio

“…Purpose This work aims to investigate the supramolecular binding interactions that occur between iodinated X‐ray contrast agents (CAs) and macrocyclic…”
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The Issue of Gadolinium Retained in Tissues: Insights on the Role of Metal Complex Stability by Comparing Metal Uptake in Murine Tissues Upon the Concomitant Administration of Lanthanum- and Gadolinium-Diethylentriamminopentaacetate by Di Gregorio, Enza, Ferrauto, Giuseppe, Furlan, Chiara, Lanzardo, Stefania, Nuzzi, Raffaele, Gianolio, Eliana, Aime, Silvio

“…OBJECTIVESThe aim of the study was to explore the role of the stability of metal complexes in the processes that lead to the metal retention in the brain and…”
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The interaction between iodinated X-ray contrast agents and macrocyclic GBCAs provides a signal enhancement in T 1 -weighted MR images: Insights into the renal excretion pathways of Gd-HPDO3A and iodixanol in healthy mice by Di Gregorio, Enza, Arena, Francesca, Gianolio, Eliana, Ferrauto, Giuseppe, Aime, Silvio

“…This work aims to investigate the supramolecular binding interactions that occur between iodinated X-ray contrast agents (CAs) and macrocyclic gadolinium…”
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