Search Results - "Ferraro, T. N."

Case–control association analysis of polymorphisms in the delta-opioid receptor, OPRD1 , with cocaine and opioid addicted populations by Crist, R.C, Ambrose-Lanci, L.M, Vaswani, M, Clarke, T.K, Zeng, A, Yuan, C, Ferraro, T.N, Hakonarson, H, Kampman, K.M, Dackis, C.A, Pettinati, H.M, O’Brien, C.P, Oslin, D.W, Doyle, G.A, Lohoff, F.W, Berrettini, W.H

“…Abstract Background Addiction susceptibility and treatment responsiveness are greatly influenced by genetic factors. Sequence variation in genes involved in…”
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Functional genetic variants in the vesicular monoamine transporter 1 modulate emotion processing by Lohoff, F W, Hodge, R, Narasimhan, S, Nall, A, Ferraro, T N, Mickey, B J, Heitzeg, M M, Langenecker, S A, Zubieta, J-K, Bogdan, R, Nikolova, Y S, Drabant, E, Hariri, A R, Bevilacqua, L, Goldman, D, Doyle, G A

“…Emotional behavior is in part heritable and often disrupted in psychopathology. Identification of specific genetic variants that drive this heritability may…”
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Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction by Clarke, T.‐K., Ambrose‐Lanci, L., Ferraro, T. N., Berrettini, W. H., Kampman, K. M., Dackis, C. A., Pettinati, H. M., O’Brien, C. P., Oslin, D. W., Lohoff, F. W.

“…Genetic factors are believed to account for 30–50% of the risk for cocaine and heroin addiction. Dynorphin peptides, derived from the prodynorphin (PDYN)…”
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Opiate agonist-induced re-distribution of Wntless, a mu-opioid receptor interacting protein, in rat striatal neurons by Reyes, B.A.S., Vakharia, K., Ferraro, T.N., Levenson, R., Berrettini, W.H., Van Bockstaele, E.J.

“…Wntless (WLS), a mu-opioid receptor (MOR) interacting protein, mediates Wnt protein secretion that is critical for neuronal development. We investigated…”
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Association between variation in the human KCNJ10 potassium ion channel gene and seizure susceptibility by Buono, R.J, Lohoff, F.W, Sander, T, Sperling, M.R, O’Connor, M.J, Dlugos, D.J, Ryan, S.G, Golden, G.T, Zhao, H, Scattergood, T.M, Berrettini, W.H, Ferraro, T.N

“…Purpose: Our research program uses genetic linkage and association analysis to identify human seizure sensitivity and resistance alleles. Quantitative trait…”
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Confirmation of association between the Val66Met polymorphism in the brain-derived neurotrophic factor (BDNF) gene and bipolar I disorder by Lohoff, F.W., Sander, T., Ferraro, T.N., Dahl, J.P., Gallinat, J., Berrettini, W.H.

“…Recent studies have indicated that the brain‐derived neurotrophic factor (BDNF) gene is involved in the etiology of bipolar disorder (BPD). Two family‐based…”
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Genetic dissection of intermale aggressive behavior in BALB/cJ and A/J mice by Dow, H. C., Kreibich, A. S., Kaercher, K. A., Sankoorikal, G. M. V., Pauley, E. D., Lohoff, F. W., Ferraro, T. N., Li, H., Brodkin, E. S.

“…Aggressive behaviors are disabling, treatment refractory, and sometimes lethal symptoms of several neuropsychiatric disorders. However, currently available…”
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Confirmation of multiple seizure susceptibility QTLs on chromosome 15 in C57BL/6J and DBA/2J inbred mice by Ferraro, T N, Smith, G G, Schwebel, C L, Doyle, G A, Ruiz, S E, Oleynick, J U, Lohoff, F W, Berrettini, W H, Buono, R J

“…To confirm seizure susceptibility (SZS) quantitative trait loci (QTLs) on chromosome (chr) 15 identified previously using C57BL/6J (B6) and DBA/2J (D2) mice…”
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Chromosome 18 DNA Markers and Manic-Depressive Illness: Evidence for a Susceptibility Gene by Berrettini, Wade H., Ferraro, Thomas N., Goldin, Lynn R., Weeks, Daniel E., Detera-Wadleigh, Sevilla, Nurnberger, John I., Gershon, Elliot S.

“…In the course of a systematic genomic survey, 22 manic-depressive (bipolar) families were examined for linkage to 11 chromosome 18 pericentromeric marker loci,…”
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Mapping murine loci for seizure response to kainic acid by Ferraro, T N, Golden, G T, Smith, G G, Schork, N J, St Jean, P, Ballas, C, Choi, H, Berrettini, W H

“…Mature DBA/2J (D2) mice are very sensitive to seizures induced by various chemical and physical stimuli, whereas C57BL/6J (B6) mice are relatively seizure…”
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Acute Cocaine-Induced Seizures: Differential Sensitivity of Six Inbred Mouse Strains by Golden, G.T., Ferraro, T.N., Smith, G.G., Snyder, R.L., Jones, N.L., Berrettini, W.H.

“…Mature male and female mice from six inbred stains were tested for susceptibility to behavioral seizures induced by a single injection of cocaine. Cocaine was…”
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Sequence and genomic organization of the human G-protein Golfα gene (GNAL) on chromosome 18p11, a susceptibility region for bipolar disorder and schizophrenia by VUORISTO, J. T, BERRETTINI, W. H, OVERHAUSER, J, PROCKOP, D. J, FERRARO, T. N, ALA-KOKKO, L

“…The sequence and genomic organization of the human Golfα (GNAL) gene were determined. The human GNAL gene was found to contain 12 coding exons, and it spans…”
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Genetic influences on electrical seizure threshold by Ferraro, T.N, Golden, G.T, Snyder, R, Laibinis, M, Smith, G.G, Buono, R.J, Berrettini, W.H

“…C57BL/6J (B6) and DBA/2J (D2) mice have been characterized previously as seizure-resistant and seizure-sensitive, respectively, a distinction based primarily…”
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Analysis of candidate genes for morphine preference quantitative trait locus Mop2 by Doyle, G.A, Schwebel, C.L, Ruiz, S.E, Chou, A.D, Lai, A.T, Wang, M.-J, Smith, G.G, Buono, R.J, Berrettini, W.H, Ferraro, T.N

“…Highlights • Chr 10 morphine preference Mop2 QTL refined to 22 candidate genes. • Ppp1r14c mRNA does not differ among morphine-treated C57BL/6 and DBA/2 mice…”
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Lack of association between temporal lobe epilepsy and a novel polymorphism in the alpha 2 subunit gene (ATP1A2) of the sodium potassium transporting ATPase by Buono, R.J., Ferraro, T.N., O'Connor, M.J., Sperling, M.R., Abbey, M., Finanger, E., Lohoff, F., Mulholland, N., Berrettini, W.H.

“…Genetic linkage studies in rodents and humans have identified specific chromosomal regions harboring seizure susceptibility genes. We have identified a novel…”
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Differential susceptibility to seizures induced by systemic kainic acid treatment in mature DBA/2J and C57BL/6J mice by Ferraro, T N, Golden, G T, Smith, G G, Berrettini, W H

“…Mature DBA/2J (D2) and C57BL/6J (B6) mice aged 9-10 weeks were studied to determine susceptibility to behavioral seizures induced by kainic acid (KA) and the…”
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Cocaine Intake by Rats Correlates with Cocaine-Induced Dopamine Changes in the Nucleus Accumbens Shell by Ferraro, T.N, Golden, G.T, Berrettini, W.H, Gottheil, E, Yang, C.H, Cuppels, G.R, Vogel, W.H

“…Extracellular dopamine levels were determined by microdialysis in the core and shell of the nucleus accumbens and the frontal cortex of rats before and after…”
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Rat strain and age differences in kainic acid induced seizures by Golden, Gregory T., Smith, George G., Ferraro, Thomas N., Reyes, Patricio F.

“…This study reports comparative dose-response data for kainic acid (KA) induced seizures in juvenile (35–40 days old) and adult (70–90 days old) Wistar-Furth…”
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Quantitative trait loci for electrical seizure threshold mapped in C57BLKS/J and C57BL/10SnJ mice by Ferraro, T. N., Smith, G. G., Ballard, D., Zhao, H., Schwebel, C. L., Gupta, A., Rappaport, E. F., Ruiz, S. E., Lohoff, F. W., Doyle, G. A., Berrettini, W. H., Buono, R. J.

“…We mapped the quantitative trait loci (QTL) that contribute to the robust difference in maximal electroshock seizure threshold (MEST) between C57BLKS/J (BKS)…”
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A High-Density Genome Scan Detects Evidence for a Bipolar-Disorder Susceptibility Locus on 13q32 and Other Potential Loci on 1q32 and 18p11.2 by Detera-Wadleigh, Sevilla D., Badner, Judith A., Berrettini, Wade H., Yoshikawa, Takeo, Goldin, Lynn R., Turner, Gordon, Rollins, Denise Y., Moses, Tracy, Sanders, Alan R., Karkera, Jayaprakash D., Esterling, Lisa E., Zeng, Jin, Ferraro, Thomas N., Guroff, Juliet J., Kazuba, Diane, Maxwell, Mary E., Nurnberger, John I., Gershon, Elliot S.

“…Bipolar disorder is a severe mental illness characterized by mood swings of elation and depression. Family, twin, and adoption studies suggest a complex…”
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