Search Results - "Ferraris, Davide"

TrUStAPIS: a trust requirements elicitation method for IoT by Ferraris, Davide, Fernandez-Gago, Carmen

“…The internet of things (IoT) is an environment of interconnected entities, which are identifiable, usable and controllable via the Internet. Trust is useful…”
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Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity by Wilk, Anna, Hayat, Faisal, Cunningham, Richard, Li, Jianfeng, Garavaglia, Silvia, Zamani, Leila, Ferraris, Davide M., Sykora, Peter, Andrews, Joel, Clark, Jennifer, Davis, Amanda, Chaloin, Laurent, Rizzi, Menico, Migaud, Marie, Sobol, Robert W.

“…Changes in nicotinamide adenine dinucleotide (NAD + ) levels that compromise mitochondrial function trigger release of DNA damaging reactive oxygen species…”
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Biochemical and structural investigations on phosphoribosylpyrophosphate synthetase from Mycobacterium smegmatis by Donini, Stefano, Garavaglia, Silvia, Ferraris, Davide M, Miggiano, Riccardo, Mori, Shigetarou, Shibayama, Keigo, Rizzi, Menico

“…Mycobacterium smegmatis represents one model for studying the biology of its pathogenic relative Mycobacterium tuberculosis. The structural characterization of…”
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A survey on IoT trust model frameworks by Ferraris, Davide, Fernandez-Gago, Carmen, Roman, Rodrigo, Lopez, Javier

“…Trust can be considered as a multidisciplinary concept, which is strongly related to the context and it falls in different fields such as Philosophy,…”
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Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment by Miggiano, Riccardo, Rizzi, Menico, Ferraris, Davide M

“…Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a…”
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A model-driven approach to ensure trust in the IoT by Ferraris, Davide, Fernandez-Gago, Carmen, Lopez, Javier

“…The Internet of Things (IoT) is a paradigm that permits smart entities to be interconnected anywhere and anyhow. IoT opens new opportunities but also rises new…”
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Biochemical characterization of Mycobacterium tuberculosis dihydroorotate dehydrogenase and identification of a selective inhibitor by Alberti, Marta, Sainas, Stefano, Ronchi, Erika, Lolli, Marco L., Boschi, Donatella, Rizzi, Menico, Ferraris, Davide M., Miggiano, Riccardo

“…Mycobacterium tuberculosis (MTB) is the etiologic agent of tuberculosis (TB), an ancient disease which causes 1.5 million deaths worldwide. Dihydroorotate…”
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Single-molecule imaging and molecular dynamics simulations reveal early activation of the MET receptor in cells by Li, Yunqing, Arghittu, Serena M., Dietz, Marina S., Hella, Gabriel J., Haße, Daniel, Ferraris, Davide M., Freund, Petra, Barth, Hans-Dieter, Iamele, Luisa, de Jonge, Hugo, Niemann, Hartmut H., Covino, Roberto, Heilemann, Mike

“…Embedding of cell-surface receptors into a membrane defines their dynamics but also complicates experimental characterization of their signaling complexes. The…”
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Structure of Thermococcus litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-complexed form by Ferraris, Davide M., Miggiano, Riccardo, Watanabe, Seiya, Rizzi, Menico

“…Hydroxyprolines (Hyp) are non-standard amino acids derived from the post-translational modification of proteins by prolyl hydroxylase enzymes. Some plants and…”
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Structure of Thermococcus litoralis Δ1‐pyrroline‐2‐carboxylate reductase in complex with NADH and l‐proline by Ferrario, Eugenio, Miggiano, Riccardo, Rizzi, Menico, Ferraris, Davide M.

“…l‐Hydroxyproline (l‐Hyp) is a nonstandard amino acid that is present in certain proteins, in some antibiotics and in the cell‐wall components of plants. l‐Hyp…”
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Structure of Thermococcus litoralis Δ 1 -pyrroline-2-carboxylate reductase in complex with NADH and L-proline by Ferrario, Eugenio, Miggiano, Riccardo, Rizzi, Menico, Ferraris, Davide M

“…L-Hydroxyproline (L-Hyp) is a nonstandard amino acid that is present in certain proteins, in some antibiotics and in the cell-wall components of plants. L-Hyp…”
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Structural investigations on orotate phosphoribosyltransferase from Mycobacterium tuberculosis, a key enzyme of the de novo pyrimidine biosynthesis by Donini, Stefano, Ferraris, Davide M., Miggiano, Riccardo, Massarotti, Alberto, Rizzi, Menico

“…The Mycobacterium tuberculosis orotate phosphoribosyltransferase (MtOPRT) catalyses the conversion of α-D-5-phosphoribosyl-1-pyrophosphate (PRPP) and orotate…”
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An alternative conformation of the N‐terminal loop of human dihydroorotate dehydrogenase drives binding to a potent antiproliferative agent by Alberti, Marta, Poli, Giulio, Broggini, Luca, Sainas, Stefano, Rizzi, Menico, Boschi, Donatella, Ferraris, Davide M., Martino, Elena, Ricagno, Stefano, Tuccinardi, Tiziano, Lolli, Marco L., Miggiano, Riccardo

“…Over the years, human dihydroorotate dehydrogenase (hDHODH), which is a key player in the de novo pyrimidine‐biosynthesis pathway, has been targeted in the…”
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Mycobacterium tuberculosis Molecular Determinants of Infection, Survival Strategies, and Vulnerable Targets by Ferraris, Davide M, Miggiano, Riccardo, Rossi, Franca, Rizzi, Menico

“…is the causative agent of tuberculosis, an ancient disease which, still today, represents a major threat for the world population. Despite the advances in…”
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Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2‑Hydroxypyrazolo[1,5‑a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety by Sainas, Stefano, Giorgis, Marta, Circosta, Paola, Poli, Giulio, Alberti, Marta, Passoni, Alice, Gaidano, Valentina, Pippione, Agnese C., Vitale, Nicoletta, Bonanni, Davide, Rolando, Barbara, Cignetti, Alessandro, Ramondetti, Cristina, Lanno, Alessia, Ferraris, Davide M., Canepa, Barbara, Buccinnà, Barbara, Piccinini, Marco, Rizzi, Menico, Saglio, Giuseppe, Al-Karadaghi, Salam, Boschi, Donatella, Miggiano, Riccardo, Tuccinardi, Tiziano, Lolli, Marco L.

“…In recent years, human dihydroorotate dehydrogenase inhibitors have been associated with acute myelogenous leukemia as well as studied as potent host targeting…”
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Hit discovery of Mycobacterium tuberculosis inosine 5′-monophosphate dehydrogenase, GuaB2, inhibitors by Sahu, Niteshkumar U., Singh, Vinayak, Ferraris, Davide M., Rizzi, Menico, Kharkar, Prashant S.

“…[Display omitted] •Novel Mycobacterium tuberculosis GuaB2 inhibitor (Compound 13) reported.•Moderately potent biochemical inhibition of Mtb GuaB2 by…”
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A trust model for popular smart home devices by Ferraris, Davide, Bastos, Daniel, Fernandez-Gago, Carmen, El-Moussa, Fadi

“…Nowadays, smart home devices like Amazon Echo and Google Home have reached mainstream popularity. Being in the homes of users, these devices are intrinsically…”
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Structures of citrate synthase and malate dehydrogenase of Mycobacterium tuberculosis by Ferraris, Davide M., Spallek, Ralf, Oehlmann, Wulf, Singh, Mahavir, Rizzi, Menico

“…ABSTRACT The tricarboxylic acid (TCA) cycle is a central metabolic pathway of all aerobic organisms and is responsible for the synthesis of many important…”
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A Selective Competitive Inhibitor of Aldehyde Dehydrogenase 1A3 Hinders Cancer Cell Growth, Invasiveness and Stemness In Vitro by Gelardi, Edoardo L M, Colombo, Giorgia, Picarazzi, Francesca, Ferraris, Davide M, Mangione, Andrea, Petrarolo, Giovanni, Aronica, Eleonora, Rizzi, Menico, Mori, Mattia, La Motta, Concettina, Garavaglia, Silvia

“…Aldehyde dehydrogenase 1A3 (ALDH1A3) belongs to an enzymatic superfamily composed by 19 different isoforms, with a scavenger role, involved in the oxidation of…”
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Expectations, experiences and preferences of patients and physicians in the informed consent process for clinical trials in oncology by Gangeri, Laura, Alfieri, Sara, Greco, Margherita, Scrignaro, Marta, Bianchi, Elisabetta, Casali, Paolo, Ferraris, Davide, Borreani, Claudia

“…Purpose The aim of the present study was to explore (1) informed consent (IC) representations, level of understanding, needs, and factors that influence the…”
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