Search Results - "Ferrand, Mireille"
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Endoproteolytic Cleavage of Human Thyroperoxidase
Published in The Journal of biological chemistry (11-02-2005)“…Human thyroperoxidase (hTPO), the key enzyme involved in thyroid hormone synthesis, is synthesized in the form of a 933-amino acid polypeptide that…”
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Involvement of the Pituitary-Specific Transcription Factor Pit-1 in Somatolactotrope Cell Growth and Death: An Approach Using Dominant-Negative Pit-1 Mutants
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2006)“…The anterior pituitary-specific transcription factor Pit-1 was initially identified and cloned as a transactivator of the prolactin (PRL) and GH genes and…”
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3
Increasing Diversity of Human Thyroperoxidase Generated by Alternative Splicing
Published in The Journal of biological chemistry (07-02-2003)“…The human thyroperoxidase (hTPO) gene is composed of 17 exons. The longest complete cDNA sequence determined so far contains a full-length hTPO (TPO1) encoding…”
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4
Purification of the human thyroid peroxidase and its identification as the microsomal antigen involved in autoimmune thyroid diseases
Published in FEBS letters (07-10-1985)“…Human thyroid peroxidase (TPO) has been purified from thyroid microsomes by immunoaffinity chromatography using a monoclonal antibody (mAb) to TPO. The eluted…”
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5
Multidrug resistance protein 3 loss promotes tumor formation by inducing senescence escape
Published in Oncogene (24-03-2016)“…Oncogenic-stress-induced senescence (OIS) is a stress response allowing normal cells, when receiving oncogenic signals, to stably arrest their proliferation…”
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6
Endoproteolytic cleavage of human thyroperoxidase: role of the propeptide in the protein folding process
Published in The Journal of biological chemistry (11-02-2005)“…Human thyroperoxidase (hTPO), the key enzyme involved in thyroid hormone synthesis, is synthesized in the form of a 933-amino acid polypeptide that…”
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Journal Article -
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Increasing Diversity of Human Thyroperoxidase Generated by Alternative Splicing. CHARACTERIZATION BY MOLECULAR CLONING OF NEW TRANSCRIPTS WITH SINGLE- AND MULTISPLICED mRNAs
Published in The Journal of biological chemistry (07-02-2003)“…The human thyroperoxidase (hTPO) gene is composed of 17 exons. The longest complete cDNA sequence determined so far contains a full-length hTPO (TPO1) encoding…”
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Journal Article -
8
Competition between calnexin and BiP in the endoplasmic reticulum can lead to the folding or degradation of human thyroperoxidase
Published in Biochemistry (Easton) (2006)“…Previous studies on the fate of human thyroperoxidase (hTPO) molecules have shown that, after being synthesized, these glycoproteins interact with calnexin and…”
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9
Involvement of the Pituitary-Specific Transcription Factor Pit-1 in Somatolactotrope Cell Growth and Death: An Approach Using Dominant-Negative Pit-1 Mutants
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2006)“…The anterior pituitary-specific transcription factor Pit-1 was initially identified and cloned as a transactivator of the prolactin (PRL) and GH genes and…”
Get full text
Journal Article -
10
Competition between Calnexin and BiP in the Endoplasmic Reticulum Can Lead to the Folding or Degradation of Human Thyroperoxidase
Published in Biochemistry (Easton) (13-06-2006)“…Previous studies on the fate of human thyroperoxidase (hTPO) molecules have shown that, after being synthesized, these glycoproteins interact with calnexin and…”
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11
Increasing diversity of human thyroperoxidase generated by alternative splicing. Characterized by molecular cloning of new transcripts with single- and multispliced mRNAs
Published in The Journal of biological chemistry (07-02-2003)“…The human thyroperoxidase (hTPO) gene is composed of 17 exons. The longest complete cDNA sequence determined so far contains a full-length hTPO (TPO1) encoding…”
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12
Differential expression of thyroperoxidase mRNA splice variants in human thyroid tumors
Published in Biochimica et biophysica acta (28-06-2004)“…The levels of human thyroperoxidase (hTPO) mRNA expression and the rates of hTPO mRNA with alternatively spliced exons 10, 14, and 16 were analyzed in normal,…”
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Relationship between immunological structure and biochemical properties of human thyroid peroxidase
Published in Endocrinology (Philadelphia) (01-09-1989)“…Although the primary structure of human thyroid peroxidase (hTPO) has been recently deciphered, little is known about its spatial conformation. Such…”
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14
Bispecific thyroglobulin and thyroperoxidase autoantibodies in patients with various thyroid and autoimmune diseases
Published in The journal of clinical endocrinology and metabolism (01-11-1994)“…Recent evidence indicates that thyroid autoimmune disorders are associated with the presence of circulating autoantibodies (aAb) with dual specificity for…”
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Immunopurification and characterization of thyroid autoantibodies with dual specificity for thyroglobulin and thyroperoxidase
Published in Autoimmunity (Chur, Switzerland) (1992)“…The presence of autoantibodies (aAbs) to thyroglobulin (TG) and thyroperoxidase (TPO) in most of the patients with autoimmune thyroid disease is now well…”
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Autoantibodies and monoclonal antibodies directed to an immunodominant antigenic region of thyroglobulin interact with thyroperoxidase through an interspecies idiotype
Published in Autoimmunity (Chur, Switzerland) (1994)“…We investigated whether thyroglobulin (TG) autoantibodies (aAb) cross-react with thyroperoxidase (TPO) through an idiotypic structure using pooled normal human…”
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Cell membrane coating with glutaraldehyde: application to a versatile solid-phase assay for thyroid membrane proteins and molecules interacting with thyroid membranes
Published in Analytical biochemistry (01-08-1985)“…In defined conditions, glutaraldehyde was shown to tightly bind cell membranes to flexible microtiter plates without significant alteration of the antigenic…”
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