Search Results - "Feron, V.J"

The FEMA GRAS assessment of aliphatic and aromatic terpene hydrocarbons used as flavor ingredients by Adams, T.B., Gavin, C. Lucas, McGowen, M.M., Waddell, W.J., Cohen, S.M., Feron, V.J., Marnett, L.J., Munro, I.C., Portoghese, P.S., Rietjens, I.M.C.M., Smith, R.L.

“…► Aliphatic and aromatic terpene hydrocarbons used as flavor ingredients and resultant exposure are reported. ► Review of absorption, distribution, metabolism…”
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The FEMA GRAS assessment of aromatic substituted secondary alcohols, ketones, and related esters used as flavor ingredients by Adams, T.B., McGowen, M.M., Williams, M.C., Cohen, S.M., Feron, V.J., Goodman, J.I., Marnett, L.J., Munro, I.C., Portoghese, P.S., Smith, R.L., Waddell, W.J.

“…This publication is the 11th in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In…”
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The FEMA GRAS assessment of hydroxy- and alkoxy-substituted benzyl derivatives used as flavor ingredients by Adams, T.B., Cohen, S.M., Doull, J., Feron, V.J., Goodman, J.I., Marnett, L.J., Munro, I.C., Portoghese, P.S., Smith, R.L., Waddell, W.J., Wagner, B.M.

“…This publication is the ninth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In…”
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The FEMA GRAS assessment of benzyl derivatives used as flavor ingredients by Adams, T.B., Cohen, S.M., Doull, J., Feron, V.J., Goodman, J.I., Marnett, L.J., Munro, I.C., Portoghese, P.S., Smith, R.L., Waddell, W.J., Wagner, B.M.

“…This publication is the eighth in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In…”
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Statistically designed experiments in a tiered approach to screen mixtures of Fusarium mycotoxins for possible interactions by Tajima, O., Schoen, E.D., Feron, V.J., Groten, J.P.

“…This paper presents a test strategy to detect interactive effects between several mycotoxins using a DNA synthesis inhibition assay in L929 cells. The joint…”
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An Analysis of the Possibility for Health Implications of Joint Actions and Interactions between Food Additives by Groten, J.P., Butler, W., Feron, V.J., Kozianowski, G., Renwick, A.G., Walker, R.

“…The possibility that structurally unrelated food additives could show either joint actions or interactions has been assessed based on their potential to share…”
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Safety evaluation of chemical mixtures and combinations of chemical and non-chemical stressors by Jonker, D, Freidig, A P, Groten, J P, de Hollander, A E M, Stierum, R H, Woutersen, R A, Feron, V J

“…Recent developments in hazard identification and risk assessment of chemical mixtures are reviewed. Empirical, descriptive approaches to study and characterize…”
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Toxicology of chemical mixtures: challenges for today and the future by Feron, V.J., Groten, J.P., Jonker, D., Cassee, F.R., van Bladeren, P.J.

“…A major challenge for the toxicologist involved in safety evaluation of chemical mixtures is to test the hypothesis that as a rule exposure to mixtures of…”
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Use of factorial designs in combination toxicity studies by Groten, J.P., Schoen, E.D., Feron, V.J.

“…The use of factorial designs, in which n chemicals are studied at x n dose levels (x treatment groups), has been put forward as one of the valuable statistical…”
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Subacute (4-wk) oral toxicity of a combination of four nephrotoxins in rats: comparison with the toxicity of the individual compounds by Jonker, D, Woutersen, R A, van Bladeren, P J, Til, H P, Feron, V J

“…In a 4-wk study, 10-wk-old Wistar rats were fed the nephrotoxins hexachloro-1,3-butadiene (HCBD), mercuric chloride, d-limonene and lysinoalanine either alone…”
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Evaluation of the oral toxicity of acetaldehyde and formaldehyde in a 4-week drinking-water study in rats by Til, H P, Woutersen, R A, Feron, V J, Clary, J J

“…A subacute oral toxicity study of acetaldehyde and formaldehyde was carried out in rats. Groups of ten male and ten female 5-wk-old rats received one of the…”
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Toxicological evaluation of chemical mixtures by Feron, V.J., Groten, J.P.

“…This paper addresses major developments in the safety evaluation of chemical mixtures during the past 15 years, reviews today's state of the art of mixture…”
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Acute (24 hr) toxicity of a combination of four nephrotoxicants in rats compared with the toxicity of the individual compounds by Jonker, D, Jones, M A, van Bladeren, P J, Woutersen, R A, Til, H P, Feron, V J

“…To identify possible hazards of combined exposure to chemicals with the same target organ, a 24-hr single dose experiment was carried out in which the renal…”
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Safety assessment of allylalkoxybenzene derivatives used as flavouring substances — methyl eugenol and estragole by Smith, R.L, Adams, T.B, Doull, J, Feron, V.J, Goodman, J.I, Marnett, L.J, Portoghese, P.S, Waddell, W.J, Wagner, B.M, Rogers, A.E, Caldwell, J, Sipes, I.G

“…This publication is the seventh in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers' Association (FEMA). In…”
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Lifetime (149-week) oral carcinogenicity study of vinyl chloride in rats by Til, H P, Feron, V J, Immel, H R

“…A lifetime (149-wk) oral carcinogenicity study of vinyl chloride monomer (VCM) was carried out. Four groups of Wistar rats were used, each consisting of 100…”
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A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils by Smith, R.L., Cohen, S.M., Doull, J., Feron, V.J., Goodman, J.I., Marnett, L.J., Portoghese, P.S., Waddell, W.J., Wagner, B.M., Hall, R.L., Higley, N.A., Lucas-Gavin, C., Adams, T.B.

“…A scientifically based guide has been developed to evaluate the safety of naturally occurring mixtures, particularly essential oils, for their intended use as…”
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The FEMA GRAS assessment of α,β-unsaturated aldehydes and related substances used as flavor ingredients by Adams, T.B., Gavin, C. Lucas, Taylor, S.V., Waddell, W.J., Cohen, S.M., Feron, V.J., Goodman, J., Rietjens, I.M.C.M., Marnett, L.J., Portoghese, P.S., Smith, R.L.

“…This publication is the 12th in a series of safety evaluations performed by the Expert Panel of the Flavor and Extract Manufacturers Association (FEMA). In…”
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4-week oral toxicity study of a combination of eight chemicals in rats: comparison with the toxicity of the individual compounds by Jonker, D, Woutersen, R A, van Bladeren, P J, Til, H P, Feron, V J

“…In a 4-wk oral toxicity study, 4-wk-old male and female Wistar rats were exposed to a combination of arbitrarily chosen chemicals comprising sodium…”
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DNA adduct formation and repair in hamster and rat tracheas exposed to benzo[a]pyrene in organ culture by Roggeband, R, Wolterbeek, A P, Melis, O W, Wittekoek, M E, Rutten, A A, Feron, V J, Baan, R A

“…Syrian golden hamsters are much more susceptible than Wistar rats to the induction of tracheal tumors by benzo[a]pyrene (B[a]P). To investigate whether this…”
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Subchronic (13-week) inhalation toxicity study of formaldehyde in male rats: 8-hour intermittent versus 8-hour continuous exposures by Wilmer, J W, Woutersen, R A, Appelman, L M, Leeman, W R, Feron, V J

“…Male Wistar rats were exposed for 13 weeks, 5 days a week to 0 (controls), 1 or 2 ppm formaldehyde continuously (8 h a day), or to 2 or 4 ppm formaldehyde…”
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