Search Results - "Ferns, Gordon A"

Targeting the Akt/PI3K Signaling Pathway as a Potential Therapeutic Strategy for the Treatment of Pancreatic Cancer by Ebrahimi, Safieh, Hosseini, Mina, Shahidsales, Soodabeh, Maftouh, Mina, Ferns, Gordon A, Ghayour-Mobarhan, Majid, Hassanian, Seyed Mahdi, Avan, Amir

“…The phosphoinositide 3 kinase AKT mammalian target of rapamycin (PI3K-AKTmTOR) signaling pathway is an important in the aetiology of pancreatic cancer (PC) and…”
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Effect of Curcumin and Its Derivates on Gastric Cancer: Molecular Mechanisms by Bahrami, Afsane, A. Ferns, Gordon

“…Gastric carcinoma is one of the most prevalent malignancies and is associated with a high mortality. Chemotherapy is the principal therapeutic option in the…”
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Role of adenomatous polyposis coli (APC) gene mutations in the pathogenesis of colorectal cancer; current status and perspectives by Aghabozorgi, Amirsaeed Sabeti, Bahreyni, Amirhossein, Soleimani, Atena, Bahrami, Afsane, Khazaei, Majid, Ferns, Gordon A., Avan, Amir, Hassanian, Seyed Mahdi

“…Colorectal cancer (CRC) is one of the most common forms of solid tumors in the world with high rates of mortality and morbidity. Most cases of CRCs are…”
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The Potential Value of the PI3K/Akt/mTOR Signaling Pathway for Assessing Prognosis in Cervical Cancer and as a Target for Therapy by Bahrami, Afsane, Hasanzadeh, Malihe, Hassanian, Seyed Mahdi, ShahidSales, Soodabeh, Ghayour‐Mobarhan, Majid, Ferns, Gordon A., Avan, Amir

“…ABSTRACT Cervical cancer is a common gynecological cancer and a leading cause of cancer‐related death in women globally. There is a need for the identification…”
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Exosomes: Emerging modulators of signal transduction in colorectal cancer from molecular understanding to clinical application by Bahrami, Afsane, Moradi Binabaj, Maryam, A. Ferns, Gordon

“…Exosomes are small cell derived membrane nano-vesicles that carry various components including lipids, proteins and nucleic acids. There is accumulating…”
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Signaling, metabolism, and cancer: An important relationship for therapeutic intervention by Vaghari‐Tabari, Mostafa, Ferns, Gordon A., Qujeq, Durdi, Andevari, Ali Nosrati, Sabahi, Zahra, Moein, Soheila

“…In cancerous cells, significant changes occur in the activity of signaling pathways affecting a wide range of cellular activities ranging from growth and…”
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Role of regulatory miRNAs of the PI3K/AKT/mTOR signaling in the pathogenesis of hepatocellular carcinoma by Rahmani, Farzad, Ziaeemehr, Aghigh, Shahidsales, Soodabeh, Gharib, Masoumeh, Khazaei, Majid, Ferns, Gordon A., Ryzhikov, Mikhail, Avan, Amir, Hassanian, Seyed M.

“…Hepatocellular carcinoma (HCC) is one of the common malignant human tumors with high morbidity worldwide. Aberrant activation of the oncogenic phosphoinositide…”
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Prediction of serum anti-HSP27 antibody titers changes using a light gradient boosting machine (LightGBM) technique by Talkhi, Nasrin, Nooghabi, Mehdi Jabbari, Esmaily, Habibollah, Maleki, Saba, Hajipoor, Mojtaba, Ferns, Gordon. A., Ghayour-Mobarhan, Majid

“…Previous studies have proposed that heat shock proteins 27 (HSP27) and its anti-HSP27 antibody titers may play a crucial role in several diseases including…”
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Dyslipidemia and cardiovascular disease risk among the MASHAD study population by Hedayatnia, Mahshad, Asadi, Zahra, Zare-Feyzabadi, Reza, Yaghooti-Khorasani, Mahdiyeh, Ghazizadeh, Hamideh, Ghaffarian-Zirak, Roshanak, Nosrati-Tirkani, Abolfazl, Mohammadi-Bajgiran, Maryam, Rohban, Mohadese, Sadabadi, Fatemeh, Rahimi, Hamid-Reza, Ghalandari, Marzieh, Ghaffari, Mohammad-Seddigh, Yousefi, Asa, Pouresmaeili, Elnaz, Besharatlou, Mohammad-Reza, Moohebati, Mohsen, Ferns, Gordon A, Esmaily, Habibollah, Ghayour-Mobarhan, Majid

“…Dyslipidemia may be defined as increased levels of serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), or a…”
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The potential for circulating microRNAs in the diagnosis of myocardial infarction: a novel approach to disease diagnosis and treatment by Gholamin, Sharareh, Pasdar, Alireza, Khorrami, Mohammad Sadegh, Mirzaei, Hamed, Mirzaei, Hamid Reza, Salehi, Rasoul, Ferns, Gordon A, Ghayour-Mobarhan, Majid, Avan, Amir

“…MicroRNAs (miRNAs) are a class of small regulatory RNAs that control several cellular processes that may contribute to development of cardiovascular disease…”
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Heavy Metal Poisoning and Cardiovascular Disease by Alissa, Eman M., Ferns, Gordon A. A.

“…Cardiovascular disease (CVD) is an increasing world health problem. Traditional risk factors fail to account for all deaths from CVD. It is mainly the…”
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Machine learning algorithms reveal potential miRNAs biomarkers in gastric cancer by Azari, Hanieh, Nazari, Elham, Mohit, Reza, Asadnia, Alireza, Maftooh, Mina, Nassiri, Mohammadreza, Hassanian, Seyed Mahdi, Ghayour-Mobarhan, Majid, Shahidsales, Soodabeh, Khazaei, Majid, Ferns, Gordon A., Avan, Amir

“…Gastric cancer is the high mortality rate cancers globally, and the current survival rate is 30% even with the use of combination therapies. Recently, mounting…”
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The dual role of microRNA-9 in gastrointestinal cancers: oncomiR or tumor suppressor? by Bahrami, Afsane, Jafari, Amirsajad, Ferns, Gordon A.

“…microRNA are noncoding endogenous RNAs of ∼ 25-nucleotide, involved in RNA silencing and controlling of cell function. Recent evidence has highlighted the…”
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Interplay between LncRNA/miRNA and TGF-β Signaling in the Tumorigenesis of Gynecological Cancer by Safavi, Pegah, Moghadam, Kimia Behrouz, Haghighi, Zahra, Ferns, Gordon A, Rahmani, Farzad

“…Gynecologic cancers are among the most common malignancies with aggressive features and poor prognosis. Tumorigenesis in gynecologic cancers is a complicated…”
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Cytokines and MicroRNA in Coronary Artery Disease by Mirzaei, Hamed, Ferns, Gordon A, Avan, Amir, Mobarhan, Majid G

“…Cardiovascular disease (CVD) is a major health problem globally. The high incidence and case fatality of CVD are, to a large extent, a consequence of its late…”
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The Association between Circulating Adipocytokine Omentin Levels and Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis by Khodashahi, Rozita, Aliakbarian, Mohsen, Ferns, Gordon A, Arjmand, Mohammad-Hassan

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver condition worldwide. NAFLD is often associated with features of Metabolic Syndrome…”
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A Mediterranean diet is associated with improved total antioxidant content of human breast milk and infant urine by Karbasi, Samira, Mohamadian, Malihe, Naseri, Mohsen, Khorasanchi, Zahra, Zarban, Asghar, Bahrami, Afsane, Ferns, Gordon A

“…The composition of breast milk (BM) is dynamic and can be influenced by maternal variables that include the diet and nutritional status. This study examined…”
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Targeting RAS signaling pathway as a potential therapeutic target in the treatment of colorectal cancer by Bahrami, Afsane, Hassanian, Seyed Mahdi, ShahidSales, Soodabeh, Farjami, Zahra, Hasanzadeh, Malihe, Anvari, Kazem, Aledavood, Amir, Maftouh, Mina, Ferns, Gordon A., Khazaei, Majid, Avan, Amir

“…The V‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) is frequently dysregulated in colorectal cancer (CRC). It is involved in the modulation of…”
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Insulinemic potential of lifestyle is associated with depression and anxiety in adults: A large community-based study by Seifi, Najmeh, Mottaghi Moghaddam Shahri, Ali, Soltankhah Beydokhti, Leyli, Mohammadi-Bajgiran, Maryam, Tahaghoghi Oliyaee, Narges, Rezaeifard, Helia, A. Ferns, Gordon, Esmaily, Habibollah, Ghayour-Mobarhan, Majid

“…We aimed to investigate the association between an empirical lifestyle index for hyperinsulinemia (ELIH), empirical lifestyle index for insulin resistance…”
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Impact of Probiotic Administration on Serum C-Reactive Protein Concentrations: Systematic Review and Meta-Analysis of Randomized Control Trials by Mazidi, Mohsen, Rezaie, Peyman, Ferns, Gordon A, Vatanparast, Hassan

“…We conducted this systematic review and meta-analysis of prospective studies to determine the effect of probiotic administration on serum C-reactive protein…”
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